Pediatrics
Showing 741-760 of 1,572 Results
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Calvin Kuo
Maureen Lyles D'Ambrogio Professor
Current Research and Scholarly InterestsWe study cancer biology, intestinal stem cells (ISC), and angiogenesis. We use primary organoid cultures of diverse tissues and tumor biopsies for immunotherapy modeling, oncogene functional screening and stem cell biology. Angiogenesis projects include blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. ISC projects apply organoid culture and ko mice to injury-inducible vs homeostatic stem cells and symmetric division mechanisms.
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Christin S Kuo
Assistant Professor of Pediatrics (Pulmonary Medicine)
BioDr. Christin Kuo is a physician-scientist in the Department of Pediatrics. The ultimate goal of her research is to integrate a cellular and molecular understanding of pulmonary neuroendocrine cells (PNECs) to discover new approaches for diagnosing and treating diverse respiratory conditions associated with NE cell dysfunction and excessive proliferation, including neuroendocrine tumors. Abnormal PNECs are found in neuroendocrine cell hyperplasia of infancy (NEHI), pulmonary carcinoids, large cell neuroendocrine carcinoma, and small cell lung cancer. Her innovative approaches to studying the development and molecular diversity of rare but fascinating neurosensory cells with single cell precision, have led to fundamental discoveries. Her lab’s current research aims to apply this knowledge to understanding diverse human pulmonary neuroendocrine cell disorders using interdisciplinary approaches. Dr. Kuo is a Maternal and Child Health Research Institute Faculty Scholar.
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Angelle Desiree LaBeaud
Professor of Pediatrics (Infectious Diseases), Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Epidemiology and Population Health and of Environmental Social Sciences
Current Research and Scholarly InterestsArthropod-borne viruses are emerging and re-emerging infections that are spreading throughout the world. Our laboratory investigates the epidemiology of arboviral infections, focusing on the burden of disease and the long-term complications on human health. In particular, Dr. LaBeaud investigates dengue, chikungunya, and Rift Valley fever viruses in Kenya, where outbreaks cause fever, arthritis, retinitis, encephalitis, and hemorrhagic fever. Our main research questions focus on the risk factors for arboviral infections, the development of diagnostic tests that can be administered in the field to quickly determine what kind of arboviral infection a person has, and the genetic and immunologic investigation of why different people respond differently to the same infection. Our long-term goals are to contribute to a deeper understanding of arboviral infections and their long-term health consequences and to optimize control strategies to prevent these emerging infections. Our laboratory also investigates the effects of antenatal and postnatal parasitic infections on vaccine responses, growth, and development of Kenyan children.
My lab at Stanford supports the field work that is ongoing in Kenya, but we also have several projects that are based locally. We strive to improve diagnostics of arboviral infections and are using Luminex technology to build a new screening assay. We also have created a Luminex based platform to assess vaccine responses against multiple pathogens. -
Norman J. Lacayo, MD
Associate Professor of Pediatrics (Hematology and Oncology)
Current Research and Scholarly InterestsPediatric Hematology/Oncology, Phase I drug studies for refractory and relapsed leukemia; genomic studies, biologic risk-stratification and treatment of acute myeloid leukemia; prediction or induction response and risk of relapse using phosphoproteomics in childhood AML; novel MRD techniques in childhood ALL.
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Mauro Lago Docampo
Postdoctoral Scholar, Cardiology
Current Research and Scholarly InterestsI have always been fascinated by the process of genetic penetrance, how two people can carry the same mutation but only one of them may be affected.
My main project focuses on understanding the role of TBX4 in the development of Pulmonary Arterial Hypertension (PAH). Mutations in this gene are related to very different diseases. In my research, I mix cellular models, gene editing, and high throughput assays to find the determinants of penetrance in the development of PAH under these conditions.
