Pediatrics
Showing 741-750 of 1,572 Results
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Calvin Kuo
Maureen Lyles D'Ambrogio Professor
Current Research and Scholarly InterestsWe study cancer biology, intestinal stem cells (ISC), and angiogenesis. We use primary organoid cultures of diverse tissues and tumor biopsies for immunotherapy modeling, oncogene functional screening and stem cell biology. Angiogenesis projects include blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. ISC projects apply organoid culture and ko mice to injury-inducible vs homeostatic stem cells and symmetric division mechanisms.
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Christin S Kuo
Assistant Professor of Pediatrics (Pulmonary Medicine)
BioDr. Christin Kuo is a physician-scientist in the Department of Pediatrics. The ultimate goal of her research is to integrate a cellular and molecular understanding of pulmonary neuroendocrine cells (PNECs) to discover new approaches for diagnosing and treating diverse respiratory conditions associated with NE cell dysfunction and excessive proliferation, including neuroendocrine tumors. Abnormal PNECs are found in neuroendocrine cell hyperplasia of infancy (NEHI), pulmonary carcinoids, large cell neuroendocrine carcinoma, and small cell lung cancer. Her innovative approaches to studying the development and molecular diversity of rare but fascinating neurosensory cells with single cell precision, have led to fundamental discoveries. Her lab’s current research aims to apply this knowledge to understanding diverse human pulmonary neuroendocrine cell disorders using interdisciplinary approaches. Dr. Kuo is a Maternal and Child Health Research Institute Faculty Scholar.
