School of Medicine
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Professor of Biomedical Data Science, of Genetics and, by courtesy, of Biology
Current Research and Scholarly InterestsMy research focuses on analyzing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. My group works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of our research is at the interface of computational biology, mathematical genetics, and evolutionary genomics.
Leah Backhus, MD, MPH, FACS
Associate Professor of Cardiothoracic Surgery (Thoracic Surgery) at the Palo Alto Veterans Affairs Health Care System
BioLeah Backhus trained in general surgery at the University of Southern California and cardiothoracic surgery at the University of California Los Angeles. She practices at Stanford Hospital and is Chief of Thoracic Surgery at the VA Palo Alto. Her surgical practice consists of general thoracic surgery with special emphasis on thoracic oncology and minimally invasive surgical techniques. She is also involved in research with the Thoracic Surgical Health Services Research group, and has grant funding through the Veterans Affairs Administration. Her current research interests are in imaging surveillance following treatment for lung cancer and cancer survivorship. She serves as a professional member of the Patient Centered Outcomes Research Institute (PCORI) Advisory Panel on Improving Healthcare Systems. She is Thoracic Track Residency Associate Program Director and serves on the ACGME Residency Review Committee for Thoracic Surgery.
The Ernest and Amelia Gallo Professor in the School of Medicine, Professor of Developmental Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsFunction of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
Professor of Radiology (General Radiology) at the Stanford University Medical Center
Current Research and Scholarly InterestsMyocardial bridges (MB) with associated upfront atherosclerotic lesions are common findings on coronary computed tomography angiography (CTA). Abnormal septal wall motion in exercise echocardiography (EE) may to be associated with MB. Intravascular ultrasound (IVUS) is considered the gold standard for the detection of MB. We investigate whether CTA is comparable to IVUS for the assessment of MB and upstream plaques in symptomatic patients with suspicion for MB raised by EE.
Associate Professor of Developmental Biology, of Computer Science and of Pediatrics (Genetics)
Current Research and Scholarly InterestsDr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.
Alfred Woodley Salter and Mabel Smith Salter Endowed Professor in Pediatrics
Current Research and Scholarly Interests1. Role of the G protein coupled receptors in regulating mitochondrial structure and function.
2. Differences between R and L ventricular responses to stress, including gene expression and miR regulation.
3. Using iPSC-derived myocytes to understand heart failure and congenital heart disease.
4. Tools for evaluation of cardiac physiology in transgenic mice and isolated cardiomyocytes.
5. Anti-body mediated rejection.
6. Biomarkers for post-transplant lymphoproliferative disorder.
Professor of Pathology at the Stanford University Medical Center
Current Research and Scholarly InterestsCardiopulmonary and pulmonary transplant medicine; diagnostic surgical pathology
Vivek Bhalla, MD, FASN, FAHA
Assistant Professor of Medicine (Nephrology) at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Bhalla's two primary research interests are in the interaction of the kidney in diabetes and hypertension. We use molecular, biochemical, and transgenic approaches to study mechanisms of physiologic and aberrant ion handling and its implications for hypertension in obesity and insulin resistance. We also study mechanisms of susceptibility to diabetic kidney disease including the role of the endothelium to regulate inflammation and kidney injury.
Sandip Biswal, MD
Associate Professor of Radiology (General Radiology) at the Stanford University Medical Center
Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.
Professor (Research) of Pediatrics (Neonatology), Emeritus
Current Research and Scholarly InterestsOur research focuses on the pathogenesis and treatment of acute and chronic neonatal lung injury and the mechanisms that regulate lung fluid balance and alveolar & pulmonary vascular development after premature birth.