School of Medicine
Showing 21-30 of 38 Results
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Francis Blankenberg
Associate Professor of Radiology (Pediatric Radiology) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsStudies on apoptotic cell death in vivo using the H MRS phenomenon.
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Terrence Blaschke
Professor of Medicine and of Molecular Pharmacology, Emeritus
Current Research and Scholarly InterestsClinical pharmacology of antiretroviral drugs
Pharmacokinetic and pharmacodynamic mechanisms of variability in drug response.
Drug development -
Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
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Paul Bollyky
Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsChronic bacterial infections are a major health care problem. Our lab is interested in understanding the host and microbial factors that perpetuate chronic infections and in developing novel therapeutic interventions to improve human health.
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Anna Maria Bombardieri
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Masters Student in Epidemiology and Clinical Research, admitted Autumn 2022Current Research and Scholarly InterestsMy overall research goal is to advance clinical practice by providing anesthesiologists with data to most effectively maintain cerebral blood flow in the perioperative period.
I am interested in the effect of the autonomic nervous system on cerebral blood flow regulation.
I intend to combine regional anesthetic techniques and noninvasive bedside cerebral blood flow monitoring to understand the effect of the sympathetic system on cerebral blood flow.
A secondary goal is to apply this new knowledge to investigate whether cervical sympathetic blocks improve long term neurological outcomes. -
John Bravman
Bing Centennial Prof, Freeman-Thornton Chair for Vice Provost for Undergrad Ed, & Dean of Fresh-Soph College, & Prof of Materials Sci & Eng, Emeritus
Biohttps://www.bucknell.edu/meet-bucknell/bucknell-leadership/meet-president-bravman
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Francesca Briganti
Instructor, Cardiovascular Institute
Current Research and Scholarly InterestsOne gene can lead to the production of many different RNA isoforms via mechanisms such as alternative promoter usage, splicing, and polyadenylation. The functional significance of many of these isoforms, their impact on cell physiology, and their regulation remain mostly controversial. Understanding the functional consequences of transcript heterogeneity will improve our understanding of gene expression regulation, broadening our ability to intervene when mutations that interfere with this regulation cause human disease.
My goal is to become an independent researcher leading an academic lab that focuses on better understanding human tissue-specific post-transcriptional regulation of gene expression and developing mechanism-based therapeutics. My general strategy is to study the function of regulatory genes and their deregulation in human disease. My specific approach is to understand the molecular mechanisms by which disease-causing mutations alter the gene function and lead to human disease. My hypothesis is that a detailed understanding of the relationship between the gene's molecular function and the disease mechanism will allow the development of first-in-class, personalized therapeutic strategies that target the disease mechanisms rather than manage symptoms independently of disease etiology.