School of Medicine
Showing 1-10 of 16 Results
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Rongxin Fang
Assistant Professor of Neurosurgery and, by courtesy, of Genetics
BioRongxin Fang received his Ph.D. in Bioinformatics and Systems Biology from the University of California, San Diego, under the mentorship of Bing Ren (2015–2019). During his doctoral training, he developed high-throughput genomic technologies and computational tools to map the structure and activity of the mammalian genome at large scale and single-cell resolution. He then applied these approaches to investigate how cis-regulatory elements - such as enhancers - control gene expression and drive the diverse transcriptional programs underlying cellular diversity in the mammalian brain. As an HHMI–Damon Runyon Postdoctoral Fellow at Harvard University (2019–2024), he worked with Xiaowei Zhuang. Rongxin developed and applied genome-scale, volumetric 3D transcriptome imaging methods to map the molecular and cellular architecture of the mammalian brain across evolution and aging. He also contributed to the collaboration with Adam Cohen and Catherine Dulac to integrate transcriptome imaging with functional neuronal imaging, identifying neuronal populations in the animal brain that underlie specific brain functions.
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Yanan Feng
Sr. Research Scientist - Basic Life, Genetics
Current Role at StanfordSenior Research Scientist, Department of Genetics, Dr. Stanley N. Cohen's lab
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Andrew Fire
George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWhile chromosomal inheritance provides cells with one means for keeping and transmitting genetic information, numerous other mechanisms have (and remain to be) discovered. We study novel cellular mechanisms that enforce genetic constancy and permit genetic change. Underlying our studies are questions of the diversity of inheritance mechanisms, how cells distinguish such mechanisms as "wanted" versus "unwanted", and of the consequences and applications of such mechanisms in health and disease.
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James Ford
Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNAdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.
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Polly Fordyce
Associate Professor of Bioengineering and of Genetics
Current Research and Scholarly InterestsThe Fordyce Lab is focused on developing new instrumentation and assays for making quantitative, systems-scale biophysical measurements of molecular interactions. Current research in the lab is focused on three main platforms: (1) arrays of valved reaction chambers for high-throughput protein expression and characterization, (2) spectrally encoded beads for multiplexed bioassays, and (3) sortable droplets and microwells for single-cell assays.
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Uta Francke
Professor of Genetics and of Pediatrics, Emerita
Current Research and Scholarly InterestsFunctional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.