School of Medicine
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Instructor, Pediatrics - Adolescent Medicine
BioShivani applies both quantitative and qualitative experimental and implementation research to develop and evaluate public health programs, that may ultimately contribute to healthy behaviors among adolescents. Her current research focuses on three key areas:
(1) Assessing youth patterns of use and perceptions about electronic cigarettes (e-cigarettes or vapes) and other substances;
(2) Understanding why youth use e-cigarettes - the impact of marketing influences and using e-cigarettes to cope with stress; and
(3) Evaluating school-based educational interventions to reduce e-cigarette use.
In addition to research, Shivani enjoys teaching research methods and mentoring residents, fellows, postdoctoral trainees and students.
Through her Ph.D., Shivani developed and evaluated an arts-based educational program to reduce mental-health-related stigma in India. The program had a large, significant and positive effect on participants - they desired greater social proximity to people living with mental health problems. During this time, she also became interested in the intersection between mental health and substance use, a common theme in her interactions with youth. She also refined her skills in statistical analysis, study design and project management. Her interdisciplinary Ph.D. research at the London School of Hygiene and Tropical Medicine was supported by the PHFI-UKC Wellcome Trust Capacity Strengthening Award (2014-18). In 2017, she received the LSHTM Public Engagement Small Grant to strengthen school teachers’ understanding of mental health problems, which resulted in a monthly column in a popular educational magazine, reaching approximately 40,000 Indian teachers every month.
Previously, Shivani designed, implemented and evaluated health communication and behavior change initiatives at the Public Health Foundation of India (PHFI) from 2008-2014. She is especially passionate about designing educational public health programs to break silences around contentious public health issues, using participatory media and entertainment-education. At PHFI, she spearheaded health communication and community engagement programs aimed at changing behavior related to healthy lifestyles, sexual and reproductive health, maternal and neonatal care, menstrual hygiene, avoidable blindness and mental health. In partnership with the Ministry of Health and Family Welfare, Government of India and community-based organizations, she led three educational interventions: a community awareness campaign, which improved treatment-seeking behavior for mental disorders in underserved areas; a website targeting young people to improve their lifestyle; and entertainment-education-based participatory action research to improve sexual and reproductive health.
Stephen J. Galli, MD
Mary Hewitt Loveless, MD, Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsThe goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.
Clinical Professor, Pediatrics - Infectious Diseases
Current Research and Scholarly InterestsThe focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts. We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients.
Rehnborg Farquhar Professor
Current Research and Scholarly InterestsThe role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
Professor of Comparative Medicine and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe medical research community has long recognized that "good well-being is good science". The lab uses an integrated interdisciplinary approach to explore this interface, while providing tangible deliverables for the well-being of human patients and research animals.
Assistant Professor of Microbiology and of Bioengineering
BioMatthias Garten, Ph.D., is an assistant professor in the department of Immunology and Microbiology and the department of Bioengineering. He is a membrane biophysicist who is driven by the question of how the malaria parasite interfaces with its host-red blood cell, how we can use the unique mechanisms of the parasite to treat malaria and to re-engineer cells for biomedical applications.
He obtained a physics master's degree from the Dresden University of Technology, Germany with a thesis in the laboratory of Dr. Petra Schwille and his Ph.D. life sciences from the University Paris Diderot, France through his work in the lab of Dr. Patricia Bassereau (Insitut Curie) investigating electrical properties of lipid membranes and protein - membrane interactions using biomimetic model systems, giant liposomes and planar lipid membranes.
In his post-doctoral work at the National Institutes of Health, Bethesda in the laboratory of Dr. Joshua Zimmerberg, he used molecular, biophysical and quantitative approaches to research the malaria parasite. His work led to the discovery of structure-function relationships that govern the host cell – parasite interface, opening research avenues to understand how the parasite connects to and controls its host cell.
Associate Professor of Radiology (Pediatric Radiology)
BioDr. Gatidis completed his medical training at the University of Tuebingen / Germany and received his Diploma in Mathematics from from the Universities of Tuebingen and Hagen / Germany. His research is focused on multiparametric oncologic medical imaging including hybrid imaging as well as on methods and applications of machine learning for medical image analysis.
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Adult-MSD) and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsThe advent of high dimensional flow cytometry has revolutionized our ability to study and visualize the human immune system. Our group combines high parameter mass cytometry (a.k.a Cytometry by Time of Flight Mass Spectrometry, CyTOF), with advanced bio-computational methods to study how the human immune system responds and adapts to acute physiological perturbations. The laboratory currently focuses on two clinical scenarios: surgical trauma and pregnancy.