School of Medicine
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Paul George, MD, PhD
Assistant Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
BioStroke is the leading cause of disability in the United States, drastically disrupting the lives of stroke survivors and their caretakers. Unfortunately, because of tight therapeutic time requirements, the majority of stroke patients are not eligible for the current medicines or interventions. The George Lab's research focuses on improving stroke diagnostics as well as engineering new methods to enhance stroke recovery. Our lab's primary focus is applying novel bioengineering techniques to understand the mechanisms of neural recovery (primarily in stroke) and discovering methods to improve patient recovery. We use rodent models of stroke combined with biomaterial techniques, stem cell transplants, and microfabrication to achieve these aims and evaluate our methods with behavior testing and various imaging techniques. Our ultimate goal is to translate these findings into clinical trials to help stroke patients.
Gerald Grant, MD, FACS
Associate Professor of Neurosurgery and, by courtesy, of Neurology at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Grant directs a Blood-brain Barrier Translational Laboratory focusing on enhancing drug delivery to brain tumors in children.
Jamshid Ghajar, MD, PhD, FACS
Clinical Professor, Neurosurgery
Current Research and Scholarly InterestsPrincipal Investigator,
“Concussion Definition Consortium – An Evidence Based Project”. Department of Defense. There are over 40 definitions of concussion but none are evidence based- i.e. come from well done studies. We will extract the most salient data from well run studies that are designed to give us a "snapshot" of what concussion is.
“Multi-Dimensional Model for Brain Trauma”. The goal is to develop a dynamic model for concussion, validate it on a retrospective dataset, and design a second study to validate it on a prospective dataset. Department of Defense.
“EYE-TRAC Advance”. Testing 10,000 subjects with normal and post concussive eye tracking. Military and civilian athletes are included. Department of Defense.
B-TEC (Brain Trauma Evidence-based Consortium). Combines Stanford B-TEC clinical trials coordinating center with the Brain Trauma Foundation's B-TEC evidence-based center to promote and coordinate an evidence-based approach to the spectrum of brain trauma from concussion to coma.