School of Medicine
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Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsOur research program has several active projects:
1.) Pulmonary Vascular Disease Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.
2.) Lung inflammation and regeneration (stem cells)
3.) Lung surfactant rheology and oxidative stress
4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms
Postdoctoral Scholar, Pulmonary and Critical Care Medicine
BioAbbas Khojasteh is a Postdoctoral Scholar at Stanford University, Cardiovascular institute. He received his Ph.D from Zurich University and completed postdoctoral neurosurgery training at Duke University, School of Medicine where he was studying experimental models of neuro modulation of glycemia and immune system in infectious diseases and inflammatory disorders such as sepsis. He evaluated the Electrical modulation efficacy in ongoing inflammation and glucose level under different conditions, such as somatotopy organizations, disease states and intensities (electrical current/potential); and he recognized different neuro fibers controlling inflammation and glycemia networks. He pushed further his idea to find out whether regulation of glycemia and inflammation by electricity is dependent on central processing and to discover a new mechanism controlling insulin production. For this novel study, he performed Spinal Cord survival surgery in mice model. One of the outcomes of this study could be applied particularly for controlling Glycemia in unresponsive patients.
Also, as a bioengineer, his previous research focused on drug discovery, cell biology and cell cultivation techniques for optimization of growth and bioengineering parameters in bioreactors particularly working on the cultivation of stem cells on microcarriers. He has experience in expression of therapeutic antibodies and production of secondary metabolites in mammalian and plant cell cultivations for therapeutics and diagnostics aims. In addition, he has been involved in several projects with pharmaceutical and cosmetic companies to develop biomedical research. For example, he established and scaled up a cell line to bioreactor at Zurich University where he produced 4g/L rosmarinc acid which is the highest secondary metabolite production to date. Moreover, he worked as a Teaching Assistant at the Faculty of Pharmacy, University of Barcelona, and he has collaborated in the supervision of more than 10 PhD, master and bachelor students.
He loves reading books related to his daily tasks; Neurosciences and Psychology to know how environmental signals shape our perceptions and run our body through brain, that is why he dedicated his PhD thesis to the Human Brain. In addition, he is interested in Political Sciences to understand how our world is being ruled; and to know our meanings (as a citizen and human being), rights, responsibilities at the state and international levels; and how much political policies can influence on our daily lives, futures and career. And of course, he does smart physical activities (like running, swimming and fitness) and socializing with his colleagues and friends.
Clinical Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine
Current Research and Scholarly InterestsDrugs and toxins-associated pulmonary arterial hypertension, clinical outcomes research, acute kidney injury in pulmonary arterial hypertension
Ware Kuschner, M.D.
Professor of Medicine (Pulmonary, Allergy and Critical Care Medicine)
Current Research and Scholarly InterestsOccupational and environmental lung disease; Pulmonary and systemic responses to toxicant inhalation; Indoor and outdoor air pollution health effects;