School of Medicine
Showing 21-30 of 49 Results
-
Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Joseph Kim
Clinical Professor, Pediatrics
BioJoseph J. Kim, MD is a Clinical Associate Professor of Pediatrics and Emergency Medicine at the Stanford University School of Medicine. Dr. Kim also serves as the Chief of the Division of Pediatric Hospital Medicine at Stanford University and as the Associate Chief Medical Officer of Stanford Children’s Health. Dr. Kim’s career has focused on medical leadership and program building in pediatric hospital medicine. He has been active locally and nationally promoting patient experience, with particular emphasis on family centered care in pediatric inpatient settings. He has participated in numerous local and national care improvement programs including efforts around bronchiolitis, inpatient asthma management, pediatric sedation, medical co-management of surgical patients and patient care progression in inpatient settings. In his hospital administrative roles he has championed safety rounding, family centered rounding, scheduled based care of inpatients, discharge planning and value based performance improvement. Dr. Kim has mentored dozens of trainees and junior faculty in healthcare leadership and program administration.
Dr. Kim received his BA in Sociology from the University of Virginia and his MD from SUNY Upstate Medical University in Syracuse. He completed his residency in pediatrics at the University of California San Francisco. Clinically, Dr. Kim practices as a Pediatric Hospitalist at Lucile Packard Children’s Hospital Stanford and at California Pacific Medical Center. -
Juliann Lipps Kim
Adjunct Clinical Professor, Pediatrics - General Pediatrics
BioDr. Juliann Kim works as a Pediatric Hospitalist for PAMF. She cares for patients in the LPCH Newborn Nursery, Packard Intermediate Care Nursery, and on the inpatient wards. She serves on several LPCH committees including Professional Performance Evaluation Committee, Perinatal Care Committee, Credentials Committee, and Care Improvement Committee. She served as the LPCH Medical Staff President from 2018-2020.
-
Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.
-
Alaina Kipps
Clinical Professor, Pediatrics - Cardiology
BioDr. Kipps grew up in Santa Cruz, California and completed her medical degree at Harvard Medical School in 2003. After general pediatrics residency at Stanford, she completed pediatric cardiology fellowship at Boston Children’s Hospital from 2006 to 2009. Having concentrated her final year of fellowship on echocardiography, she came west to practice at University of California, San Francisco until 2012. She was recruited back to Stanford in 2012 to become the medical director for acute care cardiology and she remained active in the echocardiography laboratory until 2016. In 2014 she co-founded the PAC³ network with Nicolas Madsen and co-directs this today. Her academic focus is in clinical effectiveness and quality improvement science, and she completed her Masters of Science in Epidemiology at Harvard School of Public Health in 2016. Her other significant interest is in teaching; she co-directs the pediatric residency cardiology rotation at Stanford.
-
Varvara A. Kirchner
Associate Professor of Surgery (Abdominal Transplantation) and, by courtesy, of Pediatrics
BioDr. Kirchner completed her medical school, surgical residency and multi-organ transplant fellowship in adult and pediatric liver, pancreas, kidney transplantation and total pancreatectomy with islet auto-transplantation at the University of Minnesota. She underwent further training in living donor liver transplantation and hepatobiliary surgery at the Asan Medical Center, Seoul, South Korea. Her clinical practice involves living and deceased donor liver and kidney transplantation in adult and pediatric patients as well as total pancreatectomy with islet auto-transplantation for patients with chronic and acute recurrent pancreatitis. She currently serves as Surgical Director of the Islet Cell Auto-Transplant at Stanford Children’s and Associate Director of the Living Donor Liver Transplant Program at the Division of Abdominal Transplantation. Dr. Kirchner’s research focuses on the biology of aging, cellular and solid organ transplantation. Her specific interests are in auto-islet transplantation, iPSC-derived hepatocyte therapies and liver regeneration. Dr. Kirchner's research on the impact of donor age on generation of iPSC-derived hepatocyte-like cells is supported by the NIA K08 Faculty Development Award. She is an active member of the American Society of Transplant Surgeons and the International Liver Transplantation Society.