School of Medicine
Showing 21-40 of 51 Results
David B. Lewis
Professor of Pediatrics (Immunology)
Current Research and Scholarly InterestsMy laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.
Gordon Li, MD
Professor of Neurosurgery and, by courtesy, of Neurology and of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly Interests1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery.
Jin Billy Li
Associate Professor of Genetics
Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
Postdoctoral Scholar, Immunity Transplant Infection
Current Research and Scholarly InterestsAutoimmune Diseases
Professor of Medicine (Cardiovascular Medicine)
BioDr. Liao is a Professor of Medicine and co-Director of Stanford Cardiac Amyloid Center. The major goal of her research program focuses on understanding the mechanisms that underlie the pathophysiology of heart failure and developing novel treatments to combat this process. Her laboratory has played an international leading role in the study of amyloid light chain (AL) cardiomyopathy, a rare and fatal form of cardiovascular disease. We have described the underlying pathophysiologic basis for amyloid cardiomyopathy and found that the circulating amyloidogenic light chain proteins that characterize this disease directly result in a specific cardiotoxic response. Consequently, our research work has redefined AL cardiomyopathy and has raised new treatment approaches. More recently, her research efforts have expanded to include transthyretin (ATTR) cardiac amyloidosis.
In line with her goal of revealing novel therapeutic strategies for patients with cardiovascular disease, our efforts have also focused on characterizing and harnessing endogenous cardiac regenerative mechanisms. Her laboratory initially demonstrated the therapeutic potential of exogenous primitive muscle cells delivered to the injured heart. This work was among the earliest milestones in the field and served as the basis for an international trial of cell-based therapy. Subsequently, Liao lab identified and characterized a population of cardiac progenitor cells and its relationship and dynamic activity following cardiac injury in the adult heart. Her laboratory aims to reveal the molecular mechanisms regulating the endogenous regenerative capacity of the heart and to harness such repair mechanisms for the treatment of cardiovascular disease. Dr. Liao has lectured extensively on both amyloid cardiomyopathy and stem cell biology, and have maintained a history of independent NIH funding in these areas for more than two decades.
Over the course of her academic career, she has taken the greatest pride in mentoring the next generation of scientists. Dr. Liao has had the privilege to supervise several dozen students, postdoctoral fellows, and junior faculty, many of whom have gone on to independent academic careers at the highest institutions. Her contribution to the advancement of scientific knowledge also includes lecturing at various university and academic institutions as well as at scores of conferences and symposia locally, nationally, and internationally.
Y. Joyce Liao, MD, PhD
Professor of Ophthalmology and of Neurology
Current Research and Scholarly InterestsIschemic optic neuropathy
Stem cell transplantation
Eye movement disorders
Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.
Assistant Professor (Research) of Surgery (Pediatric Surgery)
• Big data analytics for quality improvement and clinical effectiveness
• Disease biomarker discovery through multi-omics based analyses
• Assistant Professor Surgery
• B.S., Biochemistry, Fudan University, China (1990)
• M.A., Molecular and Developmental Biology, UCLA, US (1994)
• Ph.D., Biological Chemistry, UCLA, US (1996)
• Postdoctoral training, medicine/oncology/Computer science, Stanford University, US (1996-1998)
• Business administration, Leavey School of Business, Santa Clara University, US (2000-2001)
Lydia J. Lee Professor of Pediatric Cancer
Current Research and Scholarly InterestsHematology/Oncology, treatment of sarcomas of bone and soft tissue, biology of acute lymphoblastic leukemias, treatment of non-Hodgkin's lymphoma and Hodgkin's disease.
Eleni Linos, MD, MPH, DrPH
Professor of Dermatology and, by courtesy, of Epidemiology and Population Health at the Stanford University Medical Center
BioEleni Linos MD, MPH, DrPH, is Professor of Dermatology and Epidemiology at Stanford University.
Dr. Linos' work focuses on the use of technology in health, dermatology, public health, cancer prevention and the care of older adults. Dr. Linos is dually trained in epidemiology and dermatology and is the principal investigator of several NIH funded studies aimed at improving the lives of patients. She received her medical degree from Cambridge and Oxford universities in the UK, then trained in epidemiology at the Harvard School of Public Health and completed her residency at Stanford.
Joseph (Joe) Lipsick
Professor of Pathology, of Genetics and, by courtesy, of Biology
Current Research and Scholarly InterestsFunction and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.
Clinical Associate Professor, Pediatrics - Immunology and Allergy
Clinical Associate Professor, Medicine - Infectious Diseases
BioDr. Liu is a board-certified, fellowship-trained specialist in allergy/immunology and infectious disease. She is also a clinical associate professor in the Department of Medicine, Division of Infectious Diseases and the Department of Pediatrics, Division of Allergy, Immunology, and Rheumatology at Stanford University School of Medicine.
Dr. Liu treats infections in patients with compromised immune systems, whether due to a primary immune deficiency or a condition like cancer or organ transplant. She helps patients to develop tolerance to medications they are allergic to so that they can receive the best, and sometimes the only, treatments available to them. She also treats allergies to antibiotics, aspirin, NSAIDs, chemotherapy, and more. She sees patients both long term and for urgent referrals, such as in cases of perioperative anaphylaxis. Dr. Liu also helps pediatric patients manage drug and food allergies.
One of Dr. Liu’s areas of focus is helping patients with allergies to antibiotics determine when they have lost an allergy, what antibiotics they can tolerate, and when to induce tolerance to an antibiotic. This not only can benefit the patient, but also have a positive public health impact, as labeling patients with a penicillin allergy may negatively affect their care and increase use
of broad-spectrum antibiotics.
She collaborates closely with colleagues from other disciplines, including pulmonology, otolaryngology, oncology, cardiology, dermatology, anesthesiology, and surgery. Her key objective in working with referring physicians is to help them safely deliver the best care for their patients.
For patients and families, Dr. Liu strives to help them navigate their care journey with as much ease and dignity as possible during what may be the most challenging time of their life. Her goal is to offer patients options, even when it may appear that they have no options left.
Dr. Liu’s research interests include optimizing care of patients with antibiotic allergies, including through use of decision support tools.
Dr. Liu has authored articles in the New England Journal of Medicine, Journal of Immunology, Journal of Allergy and Clinical Immunology in Practice, Clinical and Experimental Allergy, Mucosal Immunology, Diagnostic Microbiology and Infectious Disease, Science, and other publications. Dr. Liu authored the book chapter “Hypersensitivity Reactions to Monoclonal Antibodies” in Drug Allergy Testing.
Dr. Liu is certified in infectious disease by the American Board of Internal Medicine and in allergy and immunology by the American Board of Allergy and Immunology. She is also a member of the American College of Physicians, Infectious Diseases Society of America, and American Academy of Allergy, Asthma, and Immunology.
She has given presentations on antibiotic allergies, drug desensitization, and aspirin-exacerbated respiratory disease, among other topics. Dr. Liu’s honors include recognition from the American Academy of Asthma, Allergy, and Immunology, the American Medical Women’s Association, and the National Institutes of Health.
Wendy Liu, MD, PhD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Liu's research interests include the role of mechanosensation in the eye as it relates to the pathophysiology of glaucoma, with the goal of finding new druggable targets in glaucoma treatment.