School of Medicine
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Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
BioDr David M. Maahs is Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University and the Lucille Packard Children’s Hospital. He earned his MD followed by Pediatric Residency at the University of New Mexico. After 3 years on New Mexico’s faculty, Dr. Maahs completed a Pediatric Endocrinology fellowship and a concurrent PhD in Epidemiology at the University of Colorado. He remained on Colorado’s faculty for 10 years, advancing to Professor of Pediatrics before moving to Stanford. Prior to his medical career, Dr. Maahs received a BA and MA in English from the University of Kansas and was inspired to pursue a medical career after serving in the Peace Corps with assignments in Tunisia and the Central African Republic.
Dr. Maahs’ leadership experiences include being a past co-Chair (2013-16) for Protocols and Publications with the Type 1 Diabetes Exchange for which he continues as a Steering Committee member and Director of International Collaborations. This complements his role as Secretary-General for the International Society of Pediatric and Adolescent Diabetes (ISPAD, 2016-20) and Editor-in-Chief for the 2018 ISPAD Clinical Practice Consensus Guidelines. He currently serves on the Professional Practice Committee for the American Diabetes Association (ADA, 2016-18), which writes the annual ADA Standards of Care. Previously, he served on the ADA Scientific Sessions committee representing the Council on Youth. He has also served on national committees for the American Heart Association, the Pediatric Endocrine Society, and multiple journal editorial boards and review committees.
His scholarly interest is improving care and preventing complications in people with type 1 diabetes (T1D). Along with Dr Peter Chase, he is author of the 12th and 13th editions of Understanding Diabetes, or ‘Pink Panther,’ which are the most widely used educational books for children newly diagnosed with T1D, distributed internationally by the Juvenile Diabetes Research Fund (JDRF). More specifically, he has conducted epidemiologic studies that help generate hypotheses for clinical studies, including trials to develop artificial pancreas systems to improve glucose control, lower disease burden, and prevent diabetic complications. He is author or co-author of over 250 research publications. His multi-disciplinary research has been funded by the JDRF, the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), the Helmsley Charitable Trust, and the National Science Foundation (NSF).
Dr Maahs is Associate Director for the recently formed and NIDDK P30 funded Stanford University Diabetes Research Center (https://sdrc.stanford.edu). His collaborations extend to his role as Principal Investigator (PI) or steering committee member for NIH funded multi-center clinical trials including the FLEX, PERL, and ACTION studies as well as multiple Artificial Pancreas clinical trials. Education, mentorship, and training leadership includes being Program Director with Dr. Georgeanna Klingensmith on the Barbara Davis Center T32 and K12 training grants in Pediatric Endocrinology while at the University of Colorado.
While in the Peace Corps, David met his wife, Christine Walravens, who is also a Pediatrician at Stanford. They enjoy outdoor activities and traveling with their children, Nicholas (20) and Natalia (15).
Professor of Pediatrics (Hematology/Oncology) and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that T cell based immunotherapy can eradicate cancers resistant to all other available therapies. Our program is focused on using genetically engineered T cells to treat cancer. We link the bench with the bedside, developing novel therapies for early phase testing in clinical trials, will simultaneously conducting intensive studies on clinical samples obtained from patients treated on immunotherapy trials.
David Magnus, Ph.D.
Thomas A. Raffin Professor in Medicine and Biomedical Ethics and Professor (Teaching) of Medicine (General Medical Disciplines)
Current Research and Scholarly InterestsGenetic testing, gene therapy, genetically engineered organisms, and the history of eugenics. Stem cell research and cloning, and egg procurement. Examining ethical issues in reproductive technologies. Organ transplantation including donation after cardiac death, ethics of listing decisions. End of life issues in both adults and children.
Instructor, Pediatrics - Hematology & Oncology
BioRobbie Majzner is an Instructor in the Division of Pediatric Hematology-Oncology at the Stanford University School of Medicine. After graduating with a BA in computer science from Columbia University, Dr. Majzner attended Harvard Medical School where he developed an interest in pediatric oncology. He completed his residency training in pediatrics at New York Presbyterian-Columbia and fellowship training in pediatric hematology-oncology at Johns Hopkins and the National Cancer Institute. During his fellowship, he began working in the laboratory of Crystal Mackall with the goal of translating the success seen with CD19 chimeric antigen receptor (CAR) T cells to pediatric solid tumors.
Dr. Majzner has generated novel CAR T cells against anaplastic lymphoma kinase (ALK), B7-H3 (CD276), and GD2. His work on the ALK CAR demonstrated that unlike native T cell receptors, synthetic CARs require high antigen density for in vivo efficacy. Using the gold standard CD19 CAR, he is continuing to probe the contribution of antigen density to CAR efficacy, and has reengineered CARs to function at lower antigen densities. He has also generated and validated a novel CAR against B7-H3, a pan-cancer antigen broadly expressed on pediatric tumors, which demonstrates exciting preclinical activity in pediatric sarcomas and brain tumors. Through his research, he aims to bring advances in cell therapy to children with incurable cancers. Clinically, Dr. Majzner cares for patients with neuroblastoma and other solid tumors. He is board certified in pediatrics and pediatric hematology-oncology.
Senior Associate Dean, Faculty Development and Diversity, Professor of Pediatrics (Infectious Diseases) and of Health Research and Policy
Current Research and Scholarly InterestsMy research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.