School of Medicine
Showing 1-14 of 14 Results
-
Dáibhid Ó Maoiléidigh, PhD
Assistant Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly InterestsThe Ó Maoiléidigh group employs mathematical and computational approaches to better understand normal hearing and hearing impairment. Because complete restoration of auditory function by artificial devices or regenerative treatments will only be possible when experiments and computational modeling align, we work closely with experimental laboratories. Our goal is to understand contemporary experimental observations, to make experimentally testable predictions, and to motivate new experiments. We are pursuing several projects.
Hair-Bundle Mechanics
Auditory and balance organs rely on hair cells to convert mechanical vibrations into electrical signals for transmission to the brain. In response to the quietest sounds we can hear, the hair cell's mechanical sensor, the hair bundle, moves by less than one-billionth of a meter. To determine how this astounding sensitivity is possible, we construct computational models of hair-bundle mechanics. By comparing models with experimental observations, we are learning how a hair bundle's geometry, material properties, and ability to move spontaneously determine its function.
Cochlear Mechanics
The cochlea contains the auditory organ that houses the sensory hair cells in mammals. Vibrations in the cochlea arising from sound are amplified more than a thousandfold by the ear's active process. New experimental techniques have additionally revealed that the cochlea vibrates in a complex manner in response to sound. We use computational models to interpret these observations and to make hypotheses about how the cochlea works. -
Hugh O'Brodovich
Arline and Pete Harman Professor for the Chair in the Department of Pediatrics in the School of Medicine, Emeritus
Current Research and Scholarly InterestsClinical:
Pulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)
Basic Science:
Lung epithelial sodium transport
Genetic influences on the development of BPD -
Lauren O'Connell
Associate Professor of Biology
Current Research and Scholarly InterestsThe O'Connell lab studies how genetic and environmental factors contribute to biological diversity and adaptation. We are particularly interested in understanding (1) how behavior evolves through changes in brain function and (2) how animal physiology evolves through repurposing existing cellular components.
-
Ruth O'Hara
Director, Spectrum, Senior Associate Dean, Research and Lowell W. and Josephine Q. Berry Professor
Current Research and Scholarly InterestsDr. O'Hara's research aims to investigate how cognitive information processing deficits subserve affective symptoms in psychiatric disorders, and interact with key brain networks integral to these disorders. To do so, she has implemented a translational, interdisciplinary program that encompasses cellular models, brain and behavioral assays of affective and cognitive information processing systems in psychiatric disorders across the lifespan.
-
Juno Obedin-Maliver
Associate Professor of Obstetrics and Gynecology (Gynecology & Gynecologic Specialties/Generalist) and, by courtesy, of Epidemiology and Population Health
BioJuno Obedin-Maliver, MD, MPH, MAS, FACOG (she/her/hers) is an Associate Professor in the Department of Obstetrics and Gynecology at Stanford University School of Medicine.
Dr. Juno Obedin-Maliver is a board-certified obstetrician/gynecologist who provides excellent clinical care and strives to advance scientific knowledge through her research.
She practices full-spectrum gynecology including outpatient, in-patient, operative, and emergency care services. This specifically includes collaborative management of cervical dysplasia and abnormal pap smears, abnormal uterine bleeding, contraception and family planning, pelvic pain, abnormal discharge, sexually transmitted infection testing and treatment, and more. She specializes in the gynecological and reproductive health care needs of sexual and gender minority people which include but are not limited to lesbian, gay, bisexual, transgender, queer and questioning (LGBTQ+) people. This interest and experience drives her research interests towards promoting the health and well-being and equity of LGBTQ people.
Dr. Obedin-Maliver, is the Co-Director of The PRIDE Study (pridestudy.org), a multi-site online prospective longitudinal cohort of sexual and gender minority individuals based at Stanford. She also serves on the medical advisory board of the University of California San Francisco Center of Excellence for Transgender Health and is helping to author the next version of the World Professional Association for Transgender Health (WPATH) Standards of Care. Dr. Obedin-Maliver has also been active in health policy including involvement in helping to legally redefine consideration of sexually intimate partner status and to remove the Medicare Non-Coverage Determination ruling on gender -affirming surgeries.
For more information about her research and career please see: pridestudy.org and http://med.stanford.edu/obedin-maliver.html -
Jelena Obradović
Professor of Education
Current Research and Scholarly InterestsAdaptation, resilience, and developmental psychopathology of disadvantaged children populations; Stress reactivity and biological sensitivity to contextual influences; Executive function and self-regulatory abilities; Effects of risk, adversity, and social status on children’s development.
-
Caroline Okorie
Clinical Associate Professor, Pediatrics - Pulmonary Medicine
BioDr. Okorie is board certified in pediatric pulmonology, sleep medicine and general pediatrics and joined the Division of Pediatric Pulmonary, Asthma and Sleep Medicine in 2018. She obtained her medical degree and Master’s in Public Health at the University of Arizona before going on to a residency and chief residency in pediatrics at Oregon Health & Science University. She completed her fellowship training in both pediatric pulmonary medicine and sleep medicine at Stanford University. She has a passion for medical education and serves as an Associate Program Director for the Pediatric Residency Program at Stanford.
She treats children with a variety of lung diseases, including: asthma, chronic cough, cystic fibrosis, chronic respiratory failure, and chronic lung disease of prematurity. Her additional training in sleep medicine allows her expertise to treat sleep disorders, including: sleep disordered breathing, parasomnias, narcolepsy, restless legs syndrome, and insomnia. -
Derick Okwan
Assistant Professor of Pathology
Current Research and Scholarly InterestsBroadly, the Okwan lab’s primary interest is to understand how and why the immune system contributes to nearly all chronic diseases. The immune system of the modern human has evolved from a history of stress to the species: famines, continual bouts of lethal pandemics, as well as major climate/environmental and migratory changes that exposed the immune system to novel threats. At the forefront of these challenges are innate immune cells, particularly neutrophils, the most abundant leukocytes. For the first time in human history – at least in the western world- we live in an era of abundance. The Okwan lab is interested in understanding how this traumatic history creates a functional mismatch for the neutrophil, which we believe underpins their roles in chronic diseases of the modern era: cancer, cardiovascular disease, neurodegeneration, and autoimmune disorders. Rather than wholesale depletion of neutrophils and innate immune cells, we seek to identify novel approaches to leverage these cells to combat various diseases.
-
Lisa A. Orloff, MD, FACS, FACE
Professor of Otolaryngology - Head & Neck Surgery (OHNS)
BioLisa A. Orloff, MD, FACS, FACE, is Director of the Endocrine Head & Neck Surgery Program and Professor in the Department of Otolaryngology — Head & Neck Surgery, Division of Head & Neck Surgery, at Stanford University School of Medicine. She is Director of the Stanford Thyroid Tumor Program within the Stanford Cancer Center. Her clinical practice focuses on the surgical management of thyroid and parathyroid tumors and disorders.
Dr. Orloff is an internationally recognized leader in the field of endocrine head and neck surgery. She is also an expert in the application of ultrasonography to the diagnosis and management of diseases of the head and neck, with an emphasis on thyroid cancer. Dr. Orloff performs minimally invasive ultrasound-guided procedures such as radiofrequency ablation for the nonsurgical management of appropriate thyroid pathology. Her background in microvascular and laryngeal surgical techniques lends a unique level of refinement to her endocrine surgical practice. A major component of her clinical work is the management of persistent or recurrent thyroid cancer. Dr. Orloff’s multidisciplinary approach to the management of endocrine head and neck disease involves collaboration with her colleagues in other specialties at Stanford and throughout the country. Dr. Orloff also studies the regeneration of tissue that has been lost as a result of cancer therapies.
Dr. Orloff received her bachelor’s degree at Stanford, and her medical degree from the University of California, Los Angeles. She completed her residency in Otolaryngology — Head & Neck Surgery at the University of Washington and a visiting fellowship in Microvascular & Reconstructive Surgery at Mount Sinai Medical Center in New York. Prior to joining the faculty at Stanford, she was the Robert K. Werbe Distinguished Professor in Head & Neck Cancer, and Chief of the Division of Head & Neck Surgery at the University of California, San Francisco (UCSF.)
Dr. Orloff served three consecutive terms as the Chair of the American Academy of Otolaryngology — Head & Neck Surgery (AAO-HNS) Endocrine Surgery committee, and served for many years as a voting member of the FDA’s Panel to evaluate medical devices for Otolaryngology. She holds leadership roles within the American Head and Neck Society, the American Thyroid Association, the American Institute of Ultrasound in Medicine, and the American College of Surgeons. She is co-chair of the ACS Thyroid, Parathyroid, and Neck Ultrasound training program and a member of the ACS National Ultrasound Faculty executive board. She is also a member of such influential teams as the National Cancer Institute (NCI) steering committee on Thyroid Cancer Clinical Trials and the Endocrine Surgery Committee of the American Association of Clinical Endocrinology (AACE). She authored the leading textbook, Head and Neck Ultrasonography (Plural Publishing), as a reference for clinicians; the second edition was published in 2017. Dr. Orloff is a former Fulbright scholar. -
Anthony Oro, MD, PhD
Eugene and Gloria Bauer Professor
Current Research and Scholarly InterestsOur lab uses the skin to answer questions about epithelial stem cell biology, differentiation and carcinogenesis using genomics, genetics, and cell biological techniques. We have studied how hedgehog signaling regulates regeneration and skin cancer, and how tumors evolve to develop resistance. We study the mechanisms of early human skin development using human embryonic stem cells. These fundamentals studies provide a greater understanding of epithelial biology and novel disease therapeutics.