School of Medicine
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Laura Jean Pisani, Ph.D.
Physical Science Research Scientist, Radiology - Diagnostic Radiology
Current Role at StanfordAssociate Director of Stanford Center for Innovation in In vivo Imaging (SCi3), Radiology
Member, Molecular Imaging Program at Stanford -
Sharon Pitteri
Professor (Research) of Radiology (Diagnostic Sciences Laboratory)
Current Research and Scholarly InterestsThe Pitteri laboratory is focused on the discovery and validation of proteins that can be used as molecular indicators of risk, diagnosis, progression, and recurrence of cancer. Proteomic technologies, predominantly mass spectrometry, are used to identify proteins in the blood that are differentially regulated and/or post-translationally modified with disease state. Using human plasma samples, tumor tissue, cancer cell lines, and genetically engineered mouse models, the origins of these proteins are being investigated. A major goal of this research is to define novel molecular signatures for breast and ovarian cancers, including particular sub-types of these diseases. This laboratory is also focused on the identification of proteins with expression restricted to the surface of cancer cells which can be used as novel targets for molecular imaging technologies.