School of Medicine
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Associate Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences) at the Stanford University Medical Center
Current Research and Scholarly InterestsResearch focused on developing interventions for management of side effects of cancer treatments (e.g., sleep disturbance, fatigue, depression, anxiety).
Pablo Paredes Castro
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
Clinical Assistant Professor (By courtesy), Epidemiology and Population Health
Current Research and Scholarly InterestsPRECISE, PERSONALIZED & AFFORDABLE WELLBEING TECHNOLOGY
Combining medicine, design, and engineering principles, we research novel technologies to keep people healthy and productive. Our goal is to discover revolutionary ways of broadly delivering both universal and selective, preventive, and self-sustaining, daily life interventions.
Karen J. Parker, PhD
Associate Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsThe Parker Lab conducts research on the biology of social functioning in monkeys, typically developing humans, and patients with social impairments.
Sergiu P. Pasca
Associate Professor of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain.
Clinical Assistant Professor, Psychiatry and Behavioral Sciences - Vaden Health Center
BioSujata Patel is a staff psychiatrist at Vaden Health Center, where she provides care to Stanford students. Her areas of interest include the transition to college and working with parents of college students.
Rafael Pelayo, MD
Clinical Professor, Psychiatry and Behavioral Sciences - Stanford Center for Sleep Sciences and Medicine
Current Research and Scholarly InterestsSleep Disorders in Adults and Children
Professor of Psychiatry and Behavioral Sciences, Emeritus
Current Research and Scholarly InterestsDevelopment and application of magnetic resonance imaging approaches for in vivo studies of human and animal brain integrity in neurodegenerative conditions, including alcoholism, HIV infection, Alzheimer's disease, and normal aging