School of Medicine
Showing 41-60 of 596 Results
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Carolyn Pan, MD
Clinical Associate Professor, Ophthalmology
BioDr. Pan is a board-certified ophthalmologist and fellowship-trained vitreoretinal surgeon. She focuses on retinal vascular diseases, macular degeneration, and surgical repair of retinal detachments, macular pathology, and complications from cataract surgery. She has co-authored peer-reviewed articles on topics ranging from optical coherence tomography imaging to embryonic stem cells for macular degeneration.
In addition to her clinical practice, she is dedicated to the education and training of medical students, residents, and fellows. As recognition of her efforts, she received the Faculty Teaching Award in 2016 from the Byers Eye Institute at Stanford University and has served as the Associate Residency Program Director since 2020.
Dr. Pan's clinical practice is mainly based at Santa Clara Valley Medical Center, where she is chief of the retina service. -
Jennifer Yi-Jiun Pan
Clinical Assistant Professor (Affiliated), Medicine - Med/Gastroenterology and Hepatology
Staff, Medicine - Med/Gastroenterology and HepatologyBioMy research interests thus far have focused on immunology, GI cancers, and improving quality of care for patients. I am passionate about understanding the different genetic and lifestyle factors that are involved in GI cancers and other colonic pathology, as well as improving systems of care to better manage the health and improve the outcomes of patients with these diseases. Towards that end, I have been involved in research in Lynch syndrome in order to bridge the gap between our current understanding of cancer risk in this high-risk population and the creation and implementation of guidelines worldwide. I also had the opportunity to work with collaborators in the International Mismatch Repair Consortium at the Department of Colorectal Medicine and Genetics with the Royal Melbourne Hospital in Australia where I saw firsthand the global efforts in the fight against colorectal cancer. In my current role as a staff gastroenterologist at the VA Palo Alto, I oversee the colorectal cancer prevention program. My goal is to continue to be part of and contribute to collaborative clinical and research efforts in order to provide the best care for our patients.
Selected NCBI Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/jennifer.pan.1/bibliography/public/ -
Minggui Pan
Clinical Associate Professor, Medicine - Med/Oncology
Clinical Associate Professor (Affiliated), Medicine - Med/OncologyBioDr. Pan is a Clinical Associate Professor of Medicine at Stanford Cancer Institute and a specialist in the Sarcoma program. Dr. Pan earned his Medical Degree from Fujian Medical University in China and PhD from Oregon Health Sciences University. He completed Internal Medicine residency at Saint Mary’s Medical Center in San Francisco and Medical Oncology fellowship at Stanford University School of Medicine. Dr. Pan has conducted both clinical and basic science research over the last three decades. His research focuses include understanding how genomic alterations impact the biological behavior of sarcoma and the prognosis of patients with sarcoma, as well as identifying new targets for developing potential new therapeutics for the treatment of sarcoma.
Dr. Pan plays basketball for exercise and walks his lovely golden retriever in his spare time. -
Vijay Pande
Adjunct Professor, Structural Biology
BioVijay Pande, Henry Dreyfus Professor of Chemistry and, by courtesy, of Structural Biology and Computer Science, also currently directs of the Stanford Program in Biophysics and the Folding@home Distribtued Computing project. His research centers on novel cloud computing simulation techniques to address problems in chemical biology. In particular, he has pioneered distributed computing methodology to break fundamental barriers in the simulation of protein and nucleic acid kinetics and thermodynamics. As director of the Folding@home project (http://folding.stanford.edu), Prof. Pande has, for the first time, directly simulated protein folding dynamics, making quantitative comparisons with experimental results, often considered a “holy grail” of computational biology. His current research also includes novel computational methods for drug design, especially in the area of protein misfolding and associated diseases such as Alzheimer’s and Huntington’s Disease.
Professor Pande studied physics at Princeton University (B.A. 1992), where he was first introduced to biophysical questions, especially in undergraduate research with Nobel Laureate P. Anderson. His doctoral research in physics under Profs. T. Tanaka and A. Grosberg at MIT (Ph.D. 1995) centered on statistical mechanical models of protein folding, suggesting new ways to design protein sequences for stability and folding properties. As a Miller Fellow under Prof. D. Rokhsar at UC Berkeley, Prof. Pande extended this methodology to examine atomistic protein models, laying the foundations for his work at Stanford University. Among numerous awards, Prof. Pande has received the Biophysical Society’s Bárány Award for Young Investigators and Protein Society’s Irving Sigal Young Investigator Award, and was named to MIT’s TR100 and elected a Fellow of the American Physical Society.
The Pande research group develops and applies new theoretical methods to understand the physical properties of biological molecules such as proteins, nucleic acids and lipid membranes, using this understanding to design synthetic systems including small-molecule therapeutics. In particular, the group examines the self-assembly properties of biomolecules. For example, how do protein and RNA molecules fold? How do proteins misfold and aggregate? How can we use this understanding to tackle misfolding related degeneration and develop small molecules to inhibit disease processes?
As these phenomena are complex, spanning molecular to mesoscopic lengths and nanosecond to millisecond timescales, the lab employs a variety of methods, including statistical mechanical analytic models, Markov State Models, and statistical and informatic methods. Other tools include Monte Carlo, Langevin dynamics, and molecular dynamics computer simulations on workstations and massively parallel supercomputers, superclusters, and worldwide distributed computing. The group has also done extensive work in the application of machine learning, pioneering traditional and deep learning approaches to cheminformatics, biophysics and drug design.
For example, simulations in all-atom detail on experimentally relevant timescales (milliseconds to seconds) have produced specific predictions of the structural and physical chemical nature of protein aggregation involved in Alzheimer’s and Huntington’s diseases. These results have fed into computational small molecule drug design methods, yielding interesting new chemical entities.
Since such problems are extremely computationally demanding, the group developed a distributed computing project for protein folding dynamics. Since its launch in October 2000, Folding@Home has attracted more than 4,000,000 PCs, and today is recognized as the most powerful supercluster in the world. Such enormous computational resources have allowed simulations of unprecedented folding timescales and statistical precision and accuracy. For more details, please visit http://pande.stanford.edu.
