School of Medicine
Showing 1-10 of 377 Results
Professor (Clinical) of Orthopaedic Surgery, Emeritus
Current Research and Scholarly InterestsThe primary subjects of my research interests over the past ten years have been clinical reviews of series of patients with a variety of pediatric orthopaedic treatable conditions. These have included neuromuscular scoliosis, developmental dislocation of the hip, and deformities in cerebral palsy.
Jack S. Remington, M.D.
Professor of Medicine, Emeritus
Current Research and Scholarly InterestsStudies on the diagnosis, epidemiology, clinical features and prevention of toxoplasmosis in the pregnant woman, the fetus and newborn, in eye disease and in the immunocompromised patient.
Richard J. Reimer, MD
Associate Professor of Neurology and, by courtesy, of Molecular and Cellular Physiology at the Palo Alto Veterans Administration Health Care System
Current Research and Scholarly InterestsReimer Lab interests
A primary interest of our lab is to understand how nerve cells make and recycle neurotransmitters, the small molecules that they use to communicate with each other. In better defining these processes we hope to achieve our long-term goal of identifying novel sites for treatment of diseases such as epilepsy and Parkinson Disease. In our studies on neurotransmitter metabolism we have focused our efforts on transporters, a functional class of proteins that move neurotransmitters and other small molecules across membranes in cells. Transporters have many characteristics that make them excellent pharmacological targets, and not surprisingly some of the most effective treatments for neuropsychiatric disorders are directed at transporters. We are specifically focusing on two groups of transporters vesicular neurotransmitter transporters that package neurotransmitters into vesicles for release, and glutamine transporters that shuttle glutamine, a precursor for two major neurotransmitters glutamate and GABA, to neurons from glia, the supporting cells that surround them. We are pursuing these goals through molecular and biochemical studies, and, in collaboration with the Huguenard and Prince labs, through physiological and biosensor based imaging studies to better understand how pharmacological targeting of these molecules will influence neurological disorders.
A second interest of our lab is to define mechanism underlying the pathology of lysosomal storage disorders. Lysosomes are membrane bound acidic intracellular organelles filled with hydrolytic enzymes that normally function as recycling centers within cells by breaking down damaged cellular macromolecules. Several degenerative diseases designated as lysosomal storage disorders (LSDs) are associated with the accumulation of material within lysosomes. Tay-Sachs disease, Neimann-Pick disease and Gaucher disease are some of the more common LSDs. For reasons that remain incompletely understood, these diseases often affect the nervous system out of proportion to other organs. As a model for LSDs we are studying the lysosomal free sialic acid storage disorders. These diseases are the result of a defect in transport of sialic acid across lysosomal membranes and are associated with mutations in the gene encoding the sialic acid transporter sialin. We are using molecular, genetic and biochemical approaches to better define the normal function of sialin and to determine how loss of sialin function leads to neurodevelopmental defects and neurodegeneration associated with the lysosomal free sialic acid storage disorders.
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric) at the Stanford University Medical Center
Current Research and Scholarly InterestsNeuro protection and neurologic outcomes in cardiac patients prior to and concurrent with cardiac surgery and catheterization
Craig S. Rosen
Associate Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences) at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly InterestsMy research aims at improving processes and outcomes of mental health care for veterans other people suffering from post-traumatic stress and other mental disorders.
My primary focus is improving access to evidence-based treatments PTSD and other psychiatric disorders. My second emphasis is using telemedicine technologies to expand access to effective care. My third interest is measurement-based care, using ongoing data on patient progress to inform patients' and clinicians' decisions.
Dwight and Vera Dunlevie Professor in Pediatric Cardiology
Current Research and Scholarly InterestsOur research program seeks to identify the cellular and molecular programs regulating vascular and lung development, through the use of cultured cells and tissues and mouse and rat models. We then determine how these programs are perturbed by genetic abnormalities or injurious processes associated with disease, focusing on pulmonary arterial hypertension (PAH), a fatal complication in children with heart defects, and a condition of unknown etiology primarily in young women.
Natalie L. Rasgon
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine) at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Rasgon has been involved in longitudinal placebo-controlled neuroendocrine studies for nearly two decades, and she has been involved in neuroendocrine and brain imaging studies of estrogen effects on depressed menopausal women for the last eight years. It should be noted that in addition to her duties as a Professor of Psychiatry and Obstetrics & Gynecology, Dr. Rasgon is also the Director of the Behavioral Neuroendocrinology Program and of the Women's Wellness Program.
Lawrence Recht, MD
Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsOur laboratory focuses on two interrelated projects: (1) assessment of glioma development within the framework of the multistage model of carcinogenesis through utilization of the rodent model of ENU neurocarcinogenesis; and (2) assessment of stem cell specification and pluripotency using an embryonic stem cell model system in which neural differentiation is induced.