School of Medicine
Showing 1-20 of 560 Results
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioI am a pediatric oncologist, and I primarily treat children who are diagnosed with soft tissue sarcomas including rhabdomyosarcoma, and children diagnosed with the eye tumor retinoblastoma, as well as children with other solid tumors.
I have two very different areas of primary research interest, both of which I pursue with passion. One focuses on global oncology, including clinical and research resource capacity building towards effective treatment and improving outcomes of children with cancer worldwide. I work with collaborators across the globe towards a common goal of improving access to diagnostic and clinical care, training of multidisciplinary teams, and building clinical resources and research capacity to develop context-informed approaches to improving cancer care and achieving better outcomes for children diagnosed with cancer irrespective of where they happen to live.
My parallel research interest, which is the focus of my laboratory, is understanding oncogenic signaling in pediatric soft tissue sarcomas, in an effort to clarify the driving biology and determinants of metastatic disease, to uncover novel targets for more effective treatment. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of cancer. We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling. Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Chiara Sabatti
Professor of Biomedical Data Science and of Statistics, and Senior Fellow at the Stanford Institute for Human-Centered Artificial Intelligence (HAI)
Current Research and Scholarly InterestsStatistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits.
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Zahra Sadat-Hossieny, MD
Clinical Assistant Professor, Adult Neurology
BioZahra Sadat-Hossieny, MD, is a board-certified neurologist who completed her fellowship in clinical epilepsy at Stanford University Hospitals and Clinics. She finished her residency in neurology at the Ohio State University Wexner Medical Center. She obtained her medical degree and a certificate in global health from the George Washington University School of Medicine and Health Sciences.
She has extensive experience treating patients with epilepsy and currently provides care through the Comprehensive Epilepsy and Comprehensive Neurology Programs at Stanford Health Care. In addition to her clinical responsibilities, Dr. Sadat-Hossieny also teaches future generations of clinicians as an assistant professor at Stanford School of Medicine in the Department of Neurology, Epilepsy, and Comprehensive Neurology.
Dr. Sadat-Hossieny has authored several peer-reviewed journal articles and book chapters. She has presented her research orally and through posters at various conferences. During her fellowship at Stanford University Hospitals and Clinics, she used advanced diagnostic techniques including video-EEG monitoring, computerized brainwave mapping, diagnostic imaging, neuropsychiatric testing, and functional mapping to accurately diagnose epilepsy and conditions imitating epilepsy. She also gained expertise in the most advanced forms of epilepsy treatment including neuromodulation, epilepsy surgery and medications specific to epilepsy. Her research focused on the cognitive effects of anti-seizure medications on patients with epilepsy and their children. She has also published on the importance of nutrient supplementation on cognition in patients taking anti-seizure medications. Her collaborations include projects that assess and improve patients’ understanding of their own seizure types. -
Agustina D Saenz
Clinical Assistant Professor, Medicine
BioAgustina Saenz is a Clinical Assistant Professor in the Division of Hospital Medicine at Stanford University School of Medicine. She earned her medical degree from the Universidad de Buenos Aires and completed her internal medicine residency, and later served as Chief Resident at Einstein Medical Center. She further pursued graduate studies at Harvard, earning a Master in Public Health from the T.H. Chan School of Public Health and a Master in Biomedical Informatics from Harvard Medical School. She also completed a Clinical Informatics fellowship at Mass General Brigham prior to joining the Stanford faculty.
Dr. Saenz’s work bridges clinical care, AI research, and health system operations. At Curai Health, she serves as a Senior Clinical Informaticist, focusing on optimizing large language models to improve diagnostic reasoning and patient safety. Her academic interests include the responsible deployment of AI in healthcare, evaluation of model generalizability, and developing system-level interventions to advance health equity. Prior to her current role, she served as Unit Medical Director and Chair of the Hiring Committee at Brigham and Women’s Hospital, where she led initiatives to enhance quality metrics and foster inclusive hiring practices. -
Rebecca Saenz
Clinical Assistant Professor, Pediatrics - Immunology
Current Research and Scholarly InterestsAllergy, Immunology, Bioengineering and Biodesign
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Samuel Ricardo Saenz, MD, MPH
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Sam Saenz was born in the Bay Area and received his bachelor’s degree in psychology from Stanford University. He completed his medical degree at UC Irvine’s Program in Medical Education for the Latino Community, and he also obtained a Master’s in Public Health from UC Berkeley. After serving as chief psychiatry resident during his psychiatry residency at Stanford, he completed a fellowship in public psychiatry at UC San Francisco. His professional interests include fostering the next generation of diverse mental health providers and community advocacy.
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Debra Safer
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
Current Research and Scholarly InterestsPrimary research interests include the nature and treatment of eating disorders
(particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery. -
Marc R. Safran, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Safrans practice focuses on arthroscopic management of hip problems as well as articular cartilage regeneration, shoulder surgery and athletic shoulder and elbow problems. He is actively involved in research in these areas.
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Manish Saggar
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsWe are a computational neuropsychiatry lab dedicated to developing computational methods to better understand brain’s overall dynamical organization in healthy and patient populations. We employ algorithms from a wide range of fields, including Applied Mathematics, Econometrics, Machine Learning, Biophysics, and Network Science.
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Kristin Sainani (n e Cobb)
Professor (Teaching) of Epidemiology and Population Health
Current Research and Scholarly InterestsScience writing, science communication, biostatistics. Research areas: osteoporosis, stress fractures, sports injuries, female athlete triad.
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Debbie C. Sakaguchi Sakai
Clinical Professor, Pediatrics
Current Research and Scholarly InterestsMedical education, shared decision making, resuscitation.
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Kathleen M. Sakamoto
Shelagh Galligan Professor in the School of Medicine
Current Research and Scholarly InterestsMy research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.
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Sarada Sakamuri, MD
Clinical Associate Professor, Adult Neurology
Clinical Associate Professor (By courtesy), NeurosurgeryBioDr. Sarada Sakamuri is a neurologist, neurophysiologist, and sonographer who specializes in the care of patients with nerve injuries and other neuromuscular disorders. As Co-Director of the Center for Peripheral Nerve Surgery, she oversees coordinated care in conjunction with the Neurology Clinic, Neurodiagnostic Lab, and Neurosurgery Clinic. She serves on multiple interdisciplinary teams focused on the care of patients with nerve conditions, including the Stanford Nerve Team, Stanford Facial Nerve Center, Stanford Women's Neurology Program, and Stanford Periprocedural Nerve Symptom Pathway.
She is an expert in the use of nerve and muscle ultrasound to diagnose and manage neuromuscular conditions. She performs advanced diagnostic evaluations of peripheral nerve conditions, integrating nerve and muscle ultrasound and neurophysiologic EMG/NCS testing at the bedside. She has advanced training in nerve and muscle ultrasound has served on the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)'s Neuromuscular Ultrasound Committee and Neuromuscular Ultrasound Exam Committee.
She also plays an active role in graduate medical education. She serves as the Program Director of the Stanford Neuromuscular Medicine Fellowship and Associate Director of the Clinical Neurophysiology/EMG Fellowship, with a total of five ACGME-accredited positions. She supervised residents in the weekly neurology resident continuity clinic for many years. She been awarded numerous teaching awards, including the Lysia S. Forno Award for outstanding contributions to resident teaching, and the American Academy of Neurology's A.B. Baker Teacher Recognition Award.
Dr. Sakamuri completed her undergraduate studies at Rutgers University, where she earned a degree in psychology with Phi Beta Kappa distinction. She completed medical school at Rutgers New Jersey Medical School in Newark, NJ, where she led multiple community service and medical education activities and was elected to the Alpha Omega Alpha and Gold Humanism Honor Societies. She moved to the Bay Area to pursue neurology residency at Stanford and served as Chief Resident in her final year of training. She then completed two years of fellowship at Stanford and the Forbes Norris MDA/ALS Research Center in EMG/Clinical Neurophysiology and Neuromuscular Medicine.
She is board-certified in Neurology and in Neuromuscular disorders by the American Board of Psychiatry and Neurology (ABPN). She is certified in EMG/NCS by the American Board of Electrodiagnostic Medicine (ABEM), and holds the ABEM Certificate of Added Qualification in Neuromuscular Ultrasound. She is a member of numerous societies, including the Performing Arts Medicine Association.