School of Medicine
Showing 781-790 of 1,296 Results
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Shruti Singh Kakan
Postdoctoral Scholar, Ophthalmology
BioI am a Biomedical Scientist with a Ph.D. in Translational Sciences. I worked with Non-Obese Diabetic (NOD) and NOD derived mice models of autoimmune Sjögren's Disease (SjD) for Biomarker Discovery and investigated disease mechanisms of autoimmune dacryoadenitis in the Lacrimal Glands. Using RNA Sequencing and autoantibody microarrays I validated microRNA biomarkers in human subjects.
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Deepti Sinha
Clinical Assistant Professor, Pediatrics - Pulmonary Medicine
BioDr. Sinha is board certified in Pediatrics and Sleep Medicine. She completed medical school in Australia and general pediatric training in Australia and USA at Royal Children’s Hospital and University of Chicago at Illinois. Her sleep medicine fellowship was completed at Stanford Hospital. She enjoys working with children of all ages. She manages both behavioral and physiological sleep concerns.
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Sidhartha Sinha
Assistant Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsThere are two primary and overlapping emphases of my research, both of which are driven and united by needs-based innovation and translational potential:
(1) Understanding the microenvironment of the inflamed versus normal gut in order to identify better therapeutic targets for people with immune-¬mediated GI disorders. Here, our investigations include understanding the influence and interactions of pharmacologic and dietary interventions on gut microbiome/metabolomic changes and the host immune response. In the context of providing patients with new understanding and solutions for their disease, I have led and advised on the design of both pilot and large clinical trials (including new FDA approved therapies) for anti-inflammatory therapies;
(2) Applying novel approaches and technologies (including natural language processing, computer vision, and reinforcement learning) to identify and address unmet clinical needs. In this area we have ongoing and published efforts in my lab to validate and develop solutions to pressing clinical needs. We have developed/led new drug delivery technologies with a multidisciplinary team that have shown strong potential in ongoing human IBD clinical trials. My lab has utilized both supervised and unsupervised approaches to analyze social media discourse and unstructured data sets for identifying patient needs that are rarely addressed in clinical settings. We have gained insights into patient perceptions around preventative health interventions, such as health screening and diet, including the dearth of evidence-based dietary recommendations to treat IBD (despite strong patient desire for solutions in this domain).
