School of Medicine
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Instructor, Institute for Stem Cell Biology and Regenerative Medicine
BioMy research interests are focused on understanding the molecular basis of early development and stem cells, as it is often aberrations in stem cells or signaling mechanisms between tissues that lead to diseased states, including tumor development and cancer progression. Knowledge of stem cells and development is also critical to develop appropriate cell-based therapies for various diseases or injuries. My prior and current works take advantage of both traditional techniques (gene targeting, lineage tracing) and state-of-the-art technologies (Single cell RNA sequencing, Chromatin Immunoprecipitation (ChIP-seq), Imaging Mass Cytometry) to elucidate fundamental molecular mechanisms underlying signaling in tissue biology.
Randall Vagelos, MD
Professor of Medicine (Cardiovascular)
Current Research and Scholarly InterestsI. Congestive Heart Failure New Medical Therapies Prognostic Evaluation Selection for Cardiac Transplantation II. Screening for Myocardial Necrosis New ECG Monitoring Devices New Serum Markers III. Screening for CAD Patients Who Have Received Radiation Rx Diabetics Being Considered for Renal Transplantation
IV. Advanced coronary and valvular disease, evaluationg candidacy for high risk interventions.
Instructor, Pediatrics - Stem Cell Transplantation
BioI am a postdoctoral scholar working with Dr. Matthew Porteus. Gene therapy has been my primary research interest during my doctoral and postdoctoral training. As a doctoral student, I studied the intracellular transport of non-viral gene delivery vectors to optimize delivery. I joined the Porteus lab to further my interest in gene therapy by applying CRISPR/Cas9 based genome editing for monogenic diseases. As a postdoctoral scholar, I have been working on using CRISPR/Cas9 technology to develop an autologous gene corrected airway stem cell therapy to treat cystic fibrosis.
Professor of Medicine (Cardiovascular)
Current Research and Scholarly InterestsMy lab is focused on understanding the mechanism mediating acute and chronic allograft failure, in particular on the role of microvascular injury in acute allograft failure and the mechanisms of mediating transplant coronary artery disease. 1. Role of microvascular injury in acute allograft failure.
Tulio Valdez, MD, MSc
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
BioDr. Tulio A Valdez is a surgeon scientist born and raised in Colombia with a subspecialty interest in Pediatric Otolaryngology. He attended medical school at Universidad Javeriana in Bogota Colombia before undertaking his residency in Otolaryngology, Head and Neck Surgery in Boston. He completed his Pediatric Otolaryngology Fellowship at Texas Children’s Hospital (2007), Houston and obtained his Master’s in Clinical and Translational Research at the University of Connecticut.
Clinically, Dr. Valdez has an interest in airway surgery and swallowing disorders. He has a special interest in the management of sinus disease in cystic fibrosis. Dr. Valdez has co-authored one textbook and numerous book chapters and scientific manuscripts. Dr. Valdez continues his clinical research in these areas, particularly with a focus on aerodigestive disorders.
Scientifically, Dr. Valdez has developed various imaging methods to diagnose otitis media and cholesteatoma a middle ear condition that can lead to hearing loss. He was part of the Laser Biomedical Research Center at Massachusetts Institute of Technology. His research includes novel imaging modalities to better diagnose ear infections one of the most common pediatric problems. His research has now expanded to include better intraoperative imaging modalities in pediatric patients to improve surgical outcomes without the need for radiation exposure.
Dr. Valdez believes in the multi-disciplinary collaborations to tackle medical problems and has co-invented various medical devices and surgical simulation models.
Keara E. Valentine
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioKeara E. Valentine, Psy.D., is a clinical assistant professor at Stanford University School of Medicine in the Psychosocial Treatment Clinic and OCD Clinic, where she specializes in the assessment and treatment of OCD and related disorders. Dr. Valentine utilizes behavioral-based therapies including Cognitive Behavioral Therapy (CBT) and Exposure and Response Prevention (ERP) with children, adolescents, and adults experiencing anxiety-related disorders.
Dr. Valentine completed an APA accredited pre-doctoral internship at Alexian Brothers Behavioral Health Hospital, where she complete a rotation in OCD and anxiety disorders and a rotation in Eating Disorders. Dr. Valentine has experience working with individuals with OCD, anxiety, and/or eating disorders at various levels of care including outpatient, partial hospitalization, residential, and inpatient.