School of Medicine
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Instructor, Pediatrics - Stem Cell Transplantation
BioI am a postdoctoral scholar working with Dr. Matthew Porteus. Gene therapy has been my primary research interest during my doctoral and postdoctoral training. As a doctoral student, I studied the intracellular transport of non-viral gene delivery vectors to optimize delivery. I joined the Porteus lab to further my interest in gene therapy by applying CRISPR/Cas9 based genome editing for monogenic diseases. As a postdoctoral scholar, I have been working on using CRISPR/Cas9 technology to develop an autologous gene corrected airway stem cell therapy to treat cystic fibrosis.
Tulio Valdez, MD, MSc
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
BioDr. Tulio A Valdez is a surgeon scientist born and raised in Colombia with a subspecialty interest in Pediatric Otolaryngology. He attended medical school at Universidad Javeriana in Bogota Colombia before undertaking his residency in Otolaryngology, Head and Neck Surgery in Boston. He completed his Pediatric Otolaryngology Fellowship at Texas Children’s Hospital (2007), Houston and obtained his Master’s in Clinical and Translational Research at the University of Connecticut.
Clinically, Dr. Valdez has an interest in airway surgery and swallowing disorders. He has a special interest in the management of sinus disease in cystic fibrosis. Dr. Valdez has co-authored one textbook and numerous book chapters and scientific manuscripts. Dr. Valdez continues his clinical research in these areas, particularly with a focus on aerodigestive disorders.
Scientifically, Dr. Valdez has developed various imaging methods to diagnose otitis media and cholesteatoma a middle ear condition that can lead to hearing loss. He was part of the Laser Biomedical Research Center at Massachusetts Institute of Technology. His research includes novel imaging modalities to better diagnose ear infections one of the most common pediatric problems. His research has now expanded to include better intraoperative imaging modalities in pediatric patients to improve surgical outcomes without the need for radiation exposure.
Dr. Valdez believes in the multi-disciplinary collaborations to tackle medical problems and has co-invented various medical devices and surgical simulation models.
Keith Van Haren, MD
Assistant Professor of Neurology and of Pediatrics
Current Research and Scholarly InterestsOur research group is dedicated to innovating care for children with degenerative brain disorders. We are particularly focused on genetic and autoimmune disorders that cause damage to the myelin (the fatty insulation around the nerves) of the brain and spinal cord. X-linked adrenoleukodystrophy (genetic) and multiple sclerosis (autoimmune) are the prototypical examples of degenerative disorders of myelin and are the two disorders we study most intensively.
Krisa Van Meurs
Rosemarie Hess Professor, Emerita
Current Research and Scholarly InterestsMy research interests include persistent pulmonary hypertension of the newborn, hypoxic respiratory failure, inhaled nitric oxide therapy, ECMO, congenital diaphragmatic hernia, neonatal clinical trials, and the use of aEEG and NIRS to detect brain injury.
Alison Schroer Vander Roest
Instructor, Pediatrics - Cardiology
BioMy research interests are in the field of cardiac mechanobiology, seeking to understand how the mechanical environment in the heart influences cell behavior and cardiac function throughout pediatric development and disease. I completed my PhD at Vanderbilt working with Dave Merryman focusing on fibroblast activation and inflammatory cell recruitment after myocardial infarction. I was excited for the opportunity to pursue postdoctoral training at Stanford, initially under the mentorship of Dr. Beth Pruitt in mechanical and bioengineering and Dr. Jim Spudich in biochemistry. My postdoctoral project has focused on the effect of myosin mutations which cause hypertrophic cardiomyopathy (HCM) using human induced pluripotent stem cell (hiPSC) derived cardiomyocytes. I have learned techniques for hydrogel micropatterning and quantification of cellular scale forces through traction force and FRET microscopy. I have also participated in many exciting collaborations across Stanford (with Dr. Alex Dunn and Dr. Sean Wu), as well as collaborators at different institutions. My background in biomedical engineering has informed my quantitative and systems-based approach to biological questions, and my current appointment in the medical school working with Dr. Dan Bernstein has provided me with the opportunity to learn more about the realities of clinical care in pediatric cardiology.
Hannes Vogel MD
Professor of Pathology and of Pediatrics (Pediatric Genetics) and, by courtesy, of Neurosurgery and of Comparative Medicine
Current Research and Scholarly InterestsMy research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology.