School of Medicine
Showing 1-38 of 38 Results
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Shin Yajima
Postdoctoral Scholar, Cardiothoracic Surgery
BioI am a board-certified cardiothoracic surgeon in Japan. Throughout my clinical experience and research, I realized that insufficient myocardial blood flow had little impact on myocardial functional recovery because percutaneous coronary intervention or coronary artery bypass grafting (CABG) could approach and supply blood flow to the superficial large coronary arteries, but not to intramyocardial microvascular arteries, especially where microvasculature was scarce or absent. Moreover, myocardial ischemia-reperfusion (I/R) impaired cardiac functional recovery in ischemic hearts, including transplanted hearts. As a result, my research interests include myocardial microvascular dysfunction and myocardial I/R injury.
During my Ph.D. studies in cardiovascular surgery, I focused on a prostacyclin analog that inhibits thromboxane A2 synthase and promotes angiogenesis and restores myocardial blood flow via proangiogenic and vasodilatory effects. Direct epicardial placement of a microform of this compound in a porcine ischemia cardiomyopathy model resulted in enhanced myocardial angiogenesis and recovery of myocardial function. Then, I developed nanoparticles (NPs) that contained this compound, which I applied to a rat ischemia myocardial reperfusion model with intravenous injection to demonstrate attenuated myocardial I/R injury with selective accumulation in the ischemic myocardium, better-preserved capillary networks, better-preserved myocardial blood flow, and a smaller infarct size. Using induced pluripotent stem cells (iPSCs) and adipose-derived mesenchymal stem cells, I have also worked on tissue engineering for myocardial regeneration. With direct implantation of cardiomyocyte sheets derived from human iPSCs onto ischemic myocardial tissue, we elucidated myocardial regeneration through thickened myocardial tissue, proangiogenic effects, improved cardiac performance, and reduced left ventricular remodeling in both small and large animals. These works have already been published (representative examples are provided below), and I have received a number of academic honors and research grants (ongoing research support; Japan Heart Foundation/Bayer Research Grant Abroad, 01/01/2022 - 12/31/2022).
My career goal is to attain leadership in academic cardiovascular surgery. During my postdoctoral fellowship, I intend to create novel therapeutic methods to improve the outcomes of ischemic heart disease through engineering analysis and the development of innovative solutions. My mentor, Dr. Woo, is a distinguished mentor with a stellar reputation for training academic surgeons, and Stanford University provides extraordinary research resources. I feel extremely fortunate to have such an ideal environment in which to carry out this project and continue bioengineering's advancement of cardiothoracic surgery. -
Yasuaki Yanagawa
Postdoctoral Scholar, Infectious Diseases
BioRNAseq for Entaoeba histolytica
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Ming Yang
Postdoctoral Scholar, Ophthalmology
BioMBBS (Hons), PhD (HKUMed), Postdoc (Stanford Medicine)
Ophthalmology
Google Scholar Citations:
https://scholar.google.com/citations?user=fiUvGFMAAAAJ&hl=en -
Zijian Yang
Postdoctoral Scholar, Radiology
BioI have long term interest in combining advanced science and technology to provide next generation healthcare system.
To reach that goal, I have developed machine learning based diagnosis model on the software end, which is combined with my hardware end work including wearable/flexible electronics and microelectronic/microfludic platforms. -
Alaa Talaat Youssef
Postdoctoral Scholar, Radiology
BioDr.Youssef is a postdoctoral fellow at the Stanford Center for Artificial Intelligence in Medicine and Imaging (AIMI), in the Department of Radiology. She received her Doctor of Philosophy (PhD) degree in Population Health and Medical Education from the Institute of Medical Science, University of Toronto in 2021, Canada. Her research interests lies at the intersection of artificial intelligence (AI) implementation and clinical evaluation. She works with multi-disciplinary research teams to assess, design, develop, and implement person-centered AI solutions that address a clinical need. Her research addresses the ethical, organizational, and workflow barriers that impede clinical adoption of AI in healthcare. Dr. Youssef co-leads the development of several AI educational programs that centers on building capacity for AI research by training diverse group of learners to facilitate safe and responsible use of AI in healthcare for public good.
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Jingru Yu
Postdoctoral Scholar, Pathology
BioJingru Yu, PhD, MPH, is a postdoctoral researcher at the Department of Pathology. She is interested in developing early diagnostic tools for brain tumors and other solid tumors using epigenomic data and aims to improve the diagnosis and prognosis of tumors.
