School of Medicine
Showing 481-490 of 1,218 Results
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Gentaro Ikeda
Instructor, Medicine - Cardiovascular Medicine
BioDr. Ikeda is a physician-scientist who develops innovative diagnostic and therapeutic modalities for patients with cardiovascular disease. Based on his clinical experience as a cardiologist, he has become aware of major clinical shortcomings, specifically in the current pharmaceutical therapies for myocardial infarction (MI) and chronic heart failure (HF). Some evidence-based drug therapies, including β-blockers, ivabradine, and renin-angiotensin-aldosterone antagonists are difficult to apply to critical patients due to adverse side effects. Drugs that have shown efficacy in basic animal experiments have failed to show significant benefits in clinical trials. To address these problems, he moved to academia to conduct translational research. During his graduate training in the Egashira Lab, he focused on drug delivery systems (DDS) that target mitochondria in animal models of MI. He obtained advanced skills in molecular biology, mitochondrial bioenergetics, and animal surgery. He realized the importance of translational research and the great potential of DDS to overcome many clinical problems. He developed nanoparticle-mediated DDS containing cyclosporine for the treatment of patients with MI. He published a first-author paper and received academic awards for his novel science. Since becoming a postdoctoral fellow in the Yang Lab, he has continued to build upon his previous training in translational research. He is currently developing an innovative therapy, namely, extracellular vesicles-mediated mitochondrial transfer for mitochondria-related diseases such as heart failure and mitochondrial disease.
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Jennifer Ikle
Adjunct Clinical Assistant Professor, Pediatrics - Endocrinology
Current Research and Scholarly InterestsJen is interested in the genetic factors that lead to abnormal beta-cell function and insulin secretion, causing disorders such as hyperinsulinism and neonatal diabetes. Jen’s current research focus is the use of zebrafish models, combined with genetics and genomics, to understand cellular and molecular mechanisms of glucose metabolism and elucidate previously unknown players involved in the regulation of insulin secretion.
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Daniel Imler
Clinical Associate Professor, Emergency Medicine
Clinical Associate Professor, PediatricsCurrent Research and Scholarly InterestsI am interested in understanding the impact of smart, agile clinical pathways to drive behavior change among providers.
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Amy M Inkster
Postdoctoral Scholar, Epidemiology
BioAmy Inkster, PhD is a Postdoctoral Scholar in the Department of Epidemiology and Population Health at Stanford University. She conducts research on epigenetic alterations in pregnancy and early life to understand the molecular levers affecting healthy development. She primarily uses large 'omics datasets to study the effect of environmental exposures on pregnancy outcomes and maternal health.
Dr. Inkster received her PhD in Medical Genetics from the University of British Columbia (Vancouver, Canada), where her research focused on evaluating DNA methylation variation in prenatal life, primarily in the context of placental epigenetics, sex differences, prenatal exposures, and X-chromosome inactivation. She holds a BSc in Chemistry. As a cross-disciplinary researcher, her work and research interests lie at the intersection of molecular mechanisms and their impacts on human health and disease at the population level. -
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .
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Prasanna Jagannathan
Associate Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsWe study innate immunity and immune regulation of Plasmodium Falciparum malaria in children and pregnant women. Our work focuses on understanding how malaria shapes the immune state in individuals following repeated exposure. We are also testing novel interventions to enhance protective immunity against malaria in children via large, randomized controlled trials. Our work in malaria has been based in Eastern Uganda, where malaria transmission is among the highest in the world.
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Safwan Jaradeh, MD
Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsClinical interests include autonomic disorders, small fiber neuropathies and the development of effective methods of testing and treating these disorders. Prior work has focused on small fiber painful and autonomic neuropathies; syndromes of orthostatic intolerance and syncope; gastrointestinal motility dysfunction; cyclic vomiting; protacted Gastroesophageal Reflux; non-allergic rhinitis syndromes; and the relationship between the autonomic nervous system and normal or abnormal sleep. Additional areas of interest include the neurology of phonation and swallowing disorders, and peripheral nerve injury and repair.
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Ted Jardetzky
Professor of Structural Biology
On Partial Leave from 12/01/2025 To 02/28/2027Current Research and Scholarly InterestsThe Jardetzky laboratory is studying the structures and mechanisms of macromolecular complexes important in viral pathogenesis, allergic hypersensitivities and the regulation of cellular growth and differentiation, with an interest in uncovering novel conceptual approaches to intervening in disease processes. Ongoing research projects include studies of paramyxovirus and herpesvirus entry mechanisms, IgE-receptor structure and function and TGF-beta ligand signaling pathways.
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Daniel Jarosz
Senior Associate Dean, Basic Science, Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.
