School of Medicine
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Amanda Kirane, MD, PhD, FACS, FSSO
Associate Professor of Surgery (General Surgery)
BioDr. Kirane is a fellowship-trained, board-certified specialist in complex general surgical oncology. She is an Assistant Professor in the Department of Surgery, Section of Surgical Oncology, at Stanford University School of Medicine. Dr. Kirane serves as Director of Cutaneous Surgical Oncology at the Stanford Cancer Center and her clinical practice focuses on the diagnosis and treatment of melanoma and other skin cancers. She partners closely with patients and families to provide the most effective treatment approach possible. For each patient, she tailors an evidence-based, personalized care plan that is innovative, comprehensive, and compassionate.
Dr. Kirane is Principal Investigator of multiple studies in melanoma and mechanisms of resistance to immunotherapy, with focus on myeloid biology. Her current interests include immune response and novel therapies in melanoma, predictive modeling of patient responses using organoid technology, and translational biomarker development. She has led research into immune therapy for earlier stage melanoma using regionally directed therapy to augment immune response in melanoma and trials in surgical care in melanoma.
The National Institutes of Health, American Society of Clinical Oncology, the Melanoma Research Alliance, and others have funded her research. She has co-authored articles on her discoveries in the Journal of Clinical Investigation, Nature Communications, Nature Genetics, Cancer Research, Journal of Surgical Oncology, Annals of Surgery, Annals of Surgical Oncology, and elsewhere. Topics include intratumoral therapy, biomarker development, macrophage biology in melanoma and immunotheraputic resistance, and patient-derived organoid modeling. Dr. Kirane has presented updates on the management of melanoma and other cancers to her peers at meetings of the American College of Surgeons, Society of Surgical Oncology, and Society for Immunotherapy in Cancer.
Dr. Kirane has earned awards for her achievements in clinical care, research, and scholarship. The Society for Immunotherapy of Cancer, Society of Surgical Oncology, Memorial Sloan Kettering Cancer Center, and other prestigious organizations have honored her work. She is a fellow of the American College of Surgeons (FACS) and Society of Surgical Oncology (FSSO). She is a member of the Society for Immunotherapy of Cancer, American Association of Cancer Research, Society for Melanoma Research, Connective Tissue Oncology Society, Association of Academic Surgeons, and Association of Women Surgeons.
She volunteers her time and expertise on behalf of the Melanoma Research Foundation, members of her community in need, STEM programs for girls, and other initiatives. She also is fellowship trained in Physician Wellness and Wellbeing and teaches somatic technique, mindfulness-based stress reduction, meditation, and breathwork. -
Varvara A. Kirchner
Associate Professor of Surgery (Abdominal Transplantation) and, by courtesy, of Pediatrics
BioDr. Kirchner completed her medical school, surgical residency and multi-organ transplant fellowship in adult and pediatric liver, pancreas, kidney transplantation and total pancreatectomy with islet auto-transplantation at the University of Minnesota. She underwent further training in living donor liver transplantation and hepatobiliary surgery at the Asan Medical Center, Seoul, South Korea. Her clinical practice involves living and deceased donor liver and kidney transplantation in adult and pediatric patients as well as total pancreatectomy with islet auto-transplantation for patients with chronic and acute recurrent pancreatitis. She currently serves as Surgical Director of the Islet Cell Auto-Transplant at Stanford Children’s and Associate Director of the Living Donor Liver Transplant Program at the Division of Abdominal Transplantation. Dr. Kirchner’s research focuses on the biology of aging, cellular and solid organ transplantation. Her specific interests are in auto-islet transplantation, iPSC-derived hepatocyte therapies and liver regeneration. Dr. Kirchner's research on the impact of donor age on generation of iPSC-derived hepatocyte-like cells is supported by the NIA K08 Faculty Development Award. She is an active member of the American Society of Transplant Surgeons and the International Liver Transplantation Society.
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Karla Kirkegaard
Violetta L. Horton Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.
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Nadia Kirmani
MD Student with Scholarly Concentration in Clinical Research / Immunology, expected graduation Spring 2027
Masters Student in Translational Research and Applied Medicine, admitted Autumn 2025BioBS in Biology & BA in English, Duke University (2019)
Honors: Summa Cum Laude, Phi Beta Kappa
Nadia's research interests include targeted cancer therapeutic development and health equity. -
Hannah Louise Kirsch, MD
Clinical Associate Professor, Adult Neurology
BioHannah Louise Kirsch, MD is a board-certified neurologist and a Clinical Assistant Professor in the Neurocritical Care Division of the Department of Neurology & Neurological Sciences at Stanford University School of Medicine.
Dr. Kirsch is also a hospitalist who pays special attention to delivering Stanford Health Care patients the best possible neurological care.
She serves on the National Institute of Neurological Disorders and Stroke committee dedicated to coma and conditions related to consciousness. She has implemented numerous neurology-centered educational activities for health care professionals from diverse specialties, including training psychiatrists on the neuropsychiatric complications of COVID-19. She also has helped educate oncologists and hematologists regarding common neurological conditions among cancer patients.
Dr. Kirsch has conducted research on a range of topics, including thrombotic complications in critically ill COVID-19 patients, advances in intracranial pressure monitoring, and predictors of outcomes in acute encephalitis. She has published her findings in Neurology, the Journal of Trauma, Emergency Medicine, and Procedures, among other journals.
She has given presentations on topics including variations in coagulation among patients with cerebral hemorrhage and the association of cerebral pressure with cardiac arrest. She has shared her discoveries at meetings of the Neurocritical Care Society and Society of Hospital Medicine.
The Neurocritical Care Society has honored her work. She also won the prestigious Leonard Tow Humanism in Medicine Award, which recognizes clinical excellence, outstanding compassion in the delivery of care, and respect for patients, families, and health care colleagues.
Dr. Kirsch received her medical degree from New York University. She completed her residency in neurology at the University of California, San Francisco, and a fellowship in neurocritical care at Columbia University. She also completed the Columbia University narrative medicine certificate program and is board certified in neurology by the American Board of Psychiatry and Neurology.
