School of Medicine
Showing 9,661-9,680 of 12,907 Results
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Mirabela Rusu
Assistant Professor of Radiology (Integrative Biomedical Imaging Informatics) and, by courtesy, of Biomedical Data Science and of Urology
Current Research and Scholarly InterestsDr. Mirabela Rusu focuses on developing analytic methods for biomedical data integration, with a particular interest in radiology-pathology fusion. Such integrative methods may be applied to create comprehensive multi-scale representations of biomedical processes and pathological conditions, thus enabling their in-depth characterization.
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Florentine Rutaganira
Assistant Professor of Biochemistry and of Developmental Biology
Current Research and Scholarly InterestsWe use chemical tools to decipher the roles of key signaling networks in choanoflagellates, single-celled organisms that are the closest living relatives of animals. Choanoflagellates produce molecular signals essential for intercellular communication in animals and the presence of these molecules in choanoflagellates suggests that signaling components needed to communicate between cells is evolutionarily ancient. We aim to uncover new understanding of animal development, physiology and disease.
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Erica Marie Rutherford
Data Wrangler, Biomedical Data Science
BioMy career spanning nine years as a data curator has given me a lot of experience and perspective into the workings of scientific data and metadata, and its organization. During my time before graduate school, I attained experience on a variety of fieldwork projects in ecology (2008-2013). During these temporary seasonal assignments, the importance of precision and care in data collection was impressed in me. When I went to graduate school at San Francisco State University (2013-2016), I gained experience in all parts of a molecular biology experiment, from fieldwork to labwork to data analysis. After graduation, I worked at a microbiome focused startup company, Second Genome, as their data curator (2016-2021). While there, I was responsible for curation of metadata for both internal studies for R&D and for clients, and for external studies being brought in for our internal Knowledgebase. While there, I developed an appreciate for ontologies, and developed a custom Second Genome Ontology to handle our metadata. I moved on to the Lattice group, located at Stanford University, where I continued to expand my skills in data curation (2021-present). I have gained experience in handling single cell datasets and their associated metadata, and curating them to meet precise standards. I strive to work collaboratively with data contributors in order to ensure FAIR data standards.
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Brian Rutt
Professor of Radiology (Radiological Sciences Lab), Emeritus
Current Research and Scholarly InterestsMy research interests center on MRI research, including high-field and high-resolution MRI technology development as well as applications of advanced MRI techniques to studying the brain, cardiovascular system and cancer.
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maura ruzhnikov
Member, Maternal & Child Health Research Institute (MCHRI)
BioChild neurologist and medical geneticist focusing on the diagnosis and management of rare neurologic disorders. Specific interests are in genetic epilepsy syndromes, childhood neurodegenerative and neurometabolic diseases and undiagnosed suspected genetic conditions.
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Charles William Ryan
Affiliate, Department Funds
Resident in SurgeryBioI was born and raised in Syracuse, New York. I first attended Onondaga Community College, where I developed a fascination with the development of complex biological systems, and then transferred to Syracuse University where I completed my B.S. in biochemistry. I next attended the University of Michigan MD/PhD program, where I used in-vitro models of human neurodevelopment to study to role of epigenetic marks in guiding neurogenesis. While at Michigan, I became interested in the prospect of harnessing in-vitro differentiation to cultivate functional tissues that can be transplanted to replace what is lost in degenerative conditions. Ophthalmology, with its microsurgical access to functionally critical cell layers, is well-positioned to capitalize on this emerging field of science to treat degenerative conditions. I am humbled and incredibly thankful to have the opportunity to pursue this aim as a SOAR resident at Stanford.
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Katherine Jane Ryan
Clinical Assistant Professor, Pediatrics - Hematology & Oncology
Clinical Assistant Professor (By courtesy), Adult NeurologyCurrent Research and Scholarly InterestsDr. Katherine “Katie” Ryan is a pediatric neuro-oncologist whose research focuses on developing and translating cellular immunotherapies for children with malignant brain tumors. She leads the first-in-human trial of GPC2-directed CAR T cells for CNS Embryonal Tumors. As a member of Stanford Children’s world-renowned pediatric brain tumor team, she diagnoses and treats children with CNS tumors while advancing innovative trial design, intracerebroventricular delivery, and correlative science.
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Tracy Rydel
Clinical Professor, Medicine - Primary Care and Population Health
BioTracy Rydel is Clinical Professor of Medicine at Stanford University School of Medicine where she holds the positions of Assistant Dean for Clerkship Education and Director, Core Clerkship in Family and Community Medicine. She has also served as the Director of Medical Student Education in the Division of Primary Care and Population Health, and was an Educator-4-CARE faculty from 2017-2020. She is a family physician with a passion for medical education. She completed the Rathmann Family Foundation Fellowship in Patient-centered Care and Medical Education in 2012, was in the first wave of peer coaches in the Peer Coaching Program under the Stanford Teaching and Mentoring Academy, and was the Director of the Practice of Medicine Year One Course at Stanford from 2013-2016. She emphasizes patient-centered care in the pursuit of clinical and educational excellence. She is frequently an invited presenter at the national conferences of the Society of Teachers of Family Medicine (STFM), and the Western Group on Educational Affairs (WGEA) regional group of the AAMC; her scholarly work focuses on medical education endeavors, including equity and justice in systems of medical education assessment. She has also presented and published on topics in nutrition education and the teaching kitchen, working with medical scribes, Entrustable Professional Activities, primary care career recruitment and mentoring, procedures training, time management in ambulatory teaching, communication skills, virtual health and telehealth, teaching gender-affirming primary care, and learning communities.
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioI am a pediatric oncologist, and I primarily treat children who are diagnosed with soft tissue sarcomas including rhabdomyosarcoma, and children diagnosed with the eye tumor retinoblastoma, as well as children with other solid tumors.
I have two very different areas of primary research interest, both of which I pursue with passion. One focuses on global oncology, including clinical and research resource capacity building towards effective treatment and improving outcomes of children with cancer worldwide. I work with collaborators across the globe towards a common goal of improving access to diagnostic and clinical care, training of multidisciplinary teams, and building clinical resources and research capacity to develop context-informed approaches to improving cancer care and achieving better outcomes for children diagnosed with cancer irrespective of where they happen to live.
My parallel research interest, which is the focus of my laboratory, is understanding oncogenic signaling in pediatric soft tissue sarcomas, in an effort to clarify the driving biology and determinants of metastatic disease, to uncover novel targets for more effective treatment. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of cancer. We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling. Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting.
