School of Medicine
Showing 91-100 of 523 Results
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Markus Covert
Shriram Chair of the Department of Bioengineering, Professor of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.
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Gerald Crabtree
David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Current Research and Scholarly InterestsChromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.
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Bianxiao Cui
Job and Gertrud Tamaki Professor of Chemistry
Current Research and Scholarly InterestsOur objective is to develop new biophysical methods to advance current understandings of cellular machinery in the complicated environment of living cells. Currently, we are focusing on four research areas: (1) Membrane curvature at the nano-bio interface; (2) Nanoelectrode arrays (NEAs) for scalable intracellular electrophysiology; (3) Electrochromic optical recording (ECORE) for neuroscience; and (4) Optical control of neurotrophin receptor tyrosine kinases.
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Maria Elizabeth Currie, MD, PhD
Clinical Assistant Professor, Cardiothoracic Surgery
BioDr. Currie is a board-certified, fellowship-trained cardiothoracic surgeon. She is also a clinical assistant professor at Stanford University School of Medicine. With subspecialty training in heart failure, Dr. Currie treats all forms of cardiomyopathy, ischemic heart disease, and valvular heart disease. She performs heart transplant, lung transplant, and combined heart-lung transplant procedures as part of a multidisciplinary team. She excels at valve surgery and the implantation of mechanical circulatory support systems.
Dr. Currie welcomes referrals from cardiologists and primary care physicians as early as possible when cardiovascular disease is suspected. Understanding that early intervention can prevent later complications, she invites communication about screening, diagnostics, and treatment strategies.
For each patient, Dr. Currie’s goal is to achieve the best possible outcome using the most advanced minimally invasive cardiac care techniques and technology available. Combined with technical expertise and a focus on excellent clinical outcomes, Dr. Currie delivers empathetic, thoughtful patient care. She ensures that patients are well informed about what they can expect both before and after their surgical procedure.
Dr. Currie is passionate about improving the safety of cardiac surgery. Her research includes translational studies on new ways to visualize anatomic structures that are difficult to see during minimally invasive surgery. One published study investigated the use of augmented reality (AR) guided by transesophageal echocardiography in minimally invasive mitral valve repair. Her work has appeared in The Journal of Thoracic and Cardiovascular Surgery, The Annals of Thoracic Surgery, The International Journal of Medical Robotics and Computer Assisted Surgery, Transplant Immunology, and other peer reviewed publications.
Dr. Currie’s interest in technological advances is rooted in her commitment to the evolution of technology and technique in the fast-changing, relatively young field of cardiac surgery. Also driving her interest is her PhD background in biomedical engineering. She has made presentations on the use of AR systems, 3D visualization technology, and robotics-assisted surgical procedures at the American Association for Thoracic Surgery Annual Meeting, International Society for Minimally Invasive Surgery Annual Scientific Meeting, and other conferences.
Dr. Currie has won numerous awards for her research achievements and scholarship. She is a Fellow of the Royal College of Surgeons of Canada. She is also a member of The Society of Thoracic Surgeons, the International Society for Heart and Lung Transplantation, the International Society for Minimally Invasive Cardiothoracic Surgery, Women in Thoracic Surgery, and the Association of Women Surgeons. With its long legacy of leadership in cardiac surgery and research, Dr. Currie feels Stanford Health Care enables her to pursue her research interests and offers her patients access to the latest innovations, along with expertise across specialties including engineering and statistics. -
Martha S. Cyert
Dr. Nancy Chang Professor
Current Research and Scholarly InterestsThe Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.
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Jeremy Dahl
Associate Professor of Radiology (Pediatric Radiology)
Current Research and Scholarly InterestsUltrasonic beamforming, imaging methods, systems, and devices.
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Hongjie Dai
The J.G. Jackson and C.J. Wood Professor of Chemistry, Emeritus
BioProfessor Dai’s research spans chemistry, physics, and materials and biomedical sciences, leading to materials with properties useful in electronics, energy storage and biomedicine. Recent developments include near-infrared-II fluorescence imaging, ultra-sensitive diagnostic assays, a fast-charging aluminum battery and inexpensive electrocatalysts that split water into oxygen and hydrogen fuels.
Born in 1966 in Shaoyang, China, Hongjie Dai began his formal studies in physics at Tsinghua U. (B.S. 1989) and applied sciences at Columbia U. (M.S. 1991). He obtained his Ph.D. from Harvard U and performed postdoctoral research with Dr. Richard Smalley. He joined the Stanford faculty in 1997, and in 2007 was named Jackson–Wood Professor of Chemistry. Among many awards, he has been recognized with the ACS Pure Chemistry Award, APS McGroddy Prize for New Materials, Julius Springer Prize for Applied Physics and Materials Research Society Mid-Career Award. He has been elected to the American Academy of Arts and Sciences, National Academy of Sciences (NAS), National Academy of Medicine (NAM) and Foreign Member of Chinese Academy of Sciences.
The Dai Laboratory has advanced the synthesis and basic understanding of carbon nanomaterials and applications in nanoelectronics, nanomedicine, energy storage and electrocatalysis.
Nanomaterials
The Dai Lab pioneered some of the now-widespread uses of chemical vapor deposition for carbon nanotube (CNT) growth, including vertically aligned nanotubes and patterned growth of single-walled CNTs on wafer substrates, facilitating fundamental studies of their intrinsic properties. The group developed the synthesis of graphene nanoribbons, and of nanocrystals and nanoparticles on CNTs and graphene with controlled degrees of oxidation, producing a class of strongly coupled hybrid materials with advanced properties for electrochemistry, electrocatalysis and photocatalysis. The lab’s synthesis of a novel plasmonic gold film has enhanced near-infrared fluorescence up to 100-fold, enabling ultra-sensitive assays of disease biomarkers.
Nanoscale Physics and Electronics
High quality nanotubes from his group’s synthesis are widely used to investigate the electrical, mechanical, optical, electro-mechanical and thermal properties of quasi-one-dimensional systems. Lab members have studied ballistic electron transport in nanotubes and demonstrated nanotube-based nanosensors, Pd ohmic contacts and ballistic field effect transistors with integrated high-kappa dielectrics.
Nanomedicine and NIR-II Imaging
Advancing biological research with CNTs and nano-graphene, group members have developed π–π stacking non-covalent functionalization chemistry, molecular cellular delivery (drugs, proteins and siRNA), in vivo anti-cancer drug delivery and in vivo photothermal ablation of cancer. Using nanotubes as novel contrast agents, lab collaborations have developed in vitro and in vivo Raman, photoacoustic and fluorescence imaging. Lab members have exploited the physics of reduced light scattering in the near-infrared-II (1000-1700nm) window and pioneered NIR-II fluorescence imaging to increase tissue penetration depth in vivo. Video-rate NIR-II imaging can measure blood flow in single vessels in real time. The lab has developed novel NIR-II fluorescence agents, including CNTs, quantum dots, conjugated polymers and small organic dyes with promise for clinical translation.
Electrocatalysis and Batteries
The Dai group’s nanocarbon–inorganic particle hybrid materials have opened new directions in energy research. Advances include electrocatalysts for oxygen reduction and water splitting catalysts including NiFe layered-double-hydroxide for oxygen evolution. Recently, the group also demonstrated an aluminum ion battery with graphite cathodes and ionic liquid electrolytes, a substantial breakthrough in battery science. -
Ronald L. Dalman MD
Dr. Walter C. Chidester Professor
Current Research and Scholarly InterestsVascular biology, arterial remodeling, aneurysm development; innovative treatment strategies for AAA, animal models of arterial disease, arterial remodeling and flow changes in spinal cord injury, genetic regulation of arterial aneurysm formation
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Rajesh Dash, MD PhD; Director of SSATHI & CardioClick
Associate Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsI have two research areas:
1) Heart disease in South Asians - genetic, metabolic, & behavioral underpinnings of an aggressive phenotype.
2) Imaging cell injury & recovery in the heart. Using Cardiac MRI to visualize signals of early injury and facilitating preventive medical therapy. Optimizing new imaging methods for viable cells to delineate live heart cells or transplanted stem cells.
