School of Medicine
Showing 101-133 of 133 Results
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Peter Sarnow
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsOur laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.
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David Schneider
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsWe study innate immunity and microbial pathogenesis. We have been studying models for a variety of bacterial infections including: Listeria, Mycobacteria, Salmonella and Streptococcus as well as some fungi, malaria and viruses. Our current focus is to determine how we recover from infections.
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Robert Siegel
Professor (Teaching) of Microbiology and Immunology
Current Research and Scholarly InterestsMy work is primarily involved in medical education and curricular development, especially in the areas of infectious disease, virology, HIV, and molecular biology. Projects included electronic applications to science education, three dimensional model building, service learning, and the development of undergraduate research projects.
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Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine) and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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Justin L. Sonnenburg
Alex and Susie Algard Endowed Professor
Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.
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Alexandra Switzer
Basic Life Research Scientist, Microbiology and Immunology
Current Role at StanfordMicrobiologist, veterinarian and data analyst in the Relman lab studying the indigenous gut microbiota of a wide range of marine and terrestrial mammals. Current research interests include characterizing microbiome assembly in neonatal mammals, host-microbiome co-evolution and patterns of microbiome diversity associated with wildlife population health.
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Sirimuvva Tadepalli
Basic Life Research Scientist, Microbiology and Immunology
BioSirimuvva Tadepalli, Ph.D. is a Research Scientist in the Department of Microbiology and Immunology at Stanford University School of Medicine where she studies the role of immune system during radiotherapy. She received her PhD in Materials Science and Engineering from Washington University in St. Louis and B.Tech. from National Institute of Technology, Warangal. Dr. Tadepalli has received various awards including the Merck Fellowship from Life Sciences Research Foundation, Dean's postdoctoral fellowship from Stanford School of Medicine and Graduate Student Gold Award from Materials Research Society. Dr. Tadepalli's research interests have spanned cancer nanomedicine, immune engineering of dendritic cells, biomaterials science and nanotechnology.
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Yuqi Tan
Postdoctoral Scholar, Microbiology and Immunology
BioDr. Tan is a computational biologist who develops computational tools to quantitatively assess cell identity, improve stem cell engineering, and understand cancer heterogeneity. As a Ph.D. student, Dr. Tan routinely performs computational and quantitative analysis on scRNA-seq data, which has resulted in several publications. Currently, at her postdoctoral position, Dr. Tan integrated single-cell omics with multiplexed image data to understand high dimensional tissue architecture in cancer. Dr.Tan's long-term aims are to integrate multi-omics to understand how different cell types and their interactions contribute to development and disease.
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Hawa Racine Thiam
Assistant Professor of Bioengineering and of Microbiology and Immunology
Current Research and Scholarly InterestsCellular Biophysical Mechanisms of Innate Immune Cells Functions
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Lucy Tompkins
Lucy Becker Professor of Medicine and Professor, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsGenetic and cellular basis of pathogenicity of Helicobacter pylori. Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections.
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Taia T. Wang, MD, PhD, MSCI
Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsLaboratory of Mechanisms in Human Immunity and Disease Pathogenesis
Antibodies are a critical component of host defense. While the importance of humoral immunity has been recognized for decades, substantial gaps in knowledge remain around how antibodies function, and how their function is regulated, in vivo. Our laboratory performs studies designed to fill in these gaps, with the goal of enabling new vaccine and therapeutic strategies to prevent human disease. My interest in this area culminated from training in medicine, RNA virus biology (PhD), and molecular antibody biology (postdoctoral training). The intersection of these topics, viral immunity and disease pathogenesis, is the focus of our work. The essential question driving our research is why a small subset of people develop severe or fatal disease during viral infection while most infections result in a subclinical or mild outcome, even in at-risk populations. Our hypothesis is that the antibody signaling pathways that are engaged during viral infection through Fc gamma receptors (FcγRs) are a key driver of these distinct outcomes. We are focused on several major unknowns to address this hypothesis: How are antibody effector functions regulated in vivo and does this change in disease? How do distinct signaling pathways engaged by IgG immune complex-FcγR interactions impact host cell genetic regulation and the ultimate inflammatory/immune response? What are the tissue-specific functions that antibodies engage? How does the heterogeneity in post-translational modifications (PTMs) of human antibodies contribute to heterogeneity in viral immunity?
Current clinical studies:
Recruiting:
An Open Label Study of IgG Fc Glycan Composition in Human Immunity
Principal Investigator: Taia T. Wang, MD, PhD
ClinicalTrials.gov Identifier:
NCT01967238 -
Priscilla Li-ning Yang
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsWe apply chemical biology approaches to study fundamental virological processes and to develop antivirals with novel mechanisms of action.
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Ellen Yeh
Associate Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsThe chemistry and biology of the unusual plastid organelle, the apicoplast, in malaria parasites
