School of Medicine
Showing 101-125 of 125 Results
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Wei Su
Postdoctoral Scholar, Molecular and Cellular Physiology
Current Research and Scholarly InterestsGlial-neuronal axis in regulation of synapse and circuit in brain development and diseases
Immune signaling and cellular metabolism in dictating T cell development and function in autoimmunity and cancer
Single cell RNA/TCR sequencing to identify cellular interaction network in regulation of neurodegeneration -
Thomas Sudhof
Avram Goldstein Professor in the School of Medicine, Professor of Neurosurgery and, by courtesy, of Neurology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsInformation transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.
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Richard Tsien
George D. Smith Professor, Emeritus
Current Research and Scholarly InterestsWe study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology.
