School of Medicine


Showing 31-40 of 149 Results

  • Ryann Fame

    Ryann Fame

    Assistant Professor of Neurosurgery

    Current Research and Scholarly InterestsEarly neural progenitors respond to extrinsic cues that maintain and support their potency. These stem/ progenitor cells are in direct contact with the cerebrospinal fluid (CSF), which acts as part of their niche. Our research program encompasses the early neural stem cell niche, neural tube closure, CSF, metabolism, and cortical neuronal development. We are dedicated to broad collaboration focused on translating an understanding of neurodevelopment and CSF biology into regenerative strategies.

  • Juan Carlos Fernandez-Miranda

    Juan Carlos Fernandez-Miranda

    Professor of Neurosurgery and, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS)

    BioDr. Juan Fernandez-Miranda is Professor of Neurosurgery and Surgical Director of the Stanford Brain Tumor, Skull Base, and Pituitary Centers. He is internationally renowned for his expertise in minimally invasive brain surgery, endoscopic skull base and pituitary surgery, open skull base surgery, and complex brain tumor surgery. He has performed nearly 3,000 cranial operations including over 1,500 endoscopic endonasal operations for pituitary tumors and other skull base lesions. He is highly regarded for his innovative contributions to the development and refinement of endoscopic endonasal skull base surgery, for his ability to select the most effective and less invasive approach to each individual patient, and for his precise knowledge of the intricate anatomy of the white matter tracts required to maximize resection and minimize morbidity on high and low grade glioma patients. He has been recently ranked by Expertscape as World-Expert (top 0.05%) on Skull Base Surgery and #1 Neurosurgeon Expert on Skull Base Tumors (pituitary adenomas, meningiomas, craniopharyngiomas, chordomas, chondrosarcomas, schwannomas and esthesioneuroblastomas) on the US Pacific Region. He is co-founder and vice-president of the International Rhoton Society and executive member of the Board of Directors of the The Neurosurgical Atlas, the largest nonprofit organization for neurosurgical education and research in the world.

    Dr. Fernandez-Miranda completed neurosurgery residency at La Paz University Hospital in Madrid, Spain. Upon completion of his residency, he was awarded the Sanitas Prize to the best medical postgraduate trainee in the country. From 2005 to 2007, he underwent fellowship training in microsurgical neuroanatomy at the University of Florida under legendary neurosurgeon Albert L. Rhoton, Jr. From 2007 to 2010 he continued subspecialty clinical training in cerebrovascular surgery at the University of Virginia, and endoscopic endonasal and open skull base surgery at University of Pittsburgh Medical Center (UPMC). During his 10-year tenure at UPMC, he pioneered endoscopic endonasal approaches to highly complex pituitary and skull base tumors, developed a world-class complex brain surgery program, and led a premier training and research program on surgical neuroanatomy and skull base surgery.

    In 2018, he was recruited to bring to Stanford his unique technical expertise and to collaborate with world-renowned Stanford colleagues across multiple disciplines, leading the establishment of one of the most preeminent centers worldwide for comprehensive treatment of complex lesions in the brain, skull base, and pituitary regions. His top priority is to provide gentle, accurate, and safe surgery, in a team-based and compassionate approach to patient care.

  • Paul Graham Fisher, MD

    Paul Graham Fisher, MD

    Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery and of Epidemiology and Population Health
    On Partial Leave from 07/15/2024 To 07/13/2025

    Current Research and Scholarly InterestsClinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors and other cancers in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies.

  • Robert Fisher, MD, PhD

    Robert Fisher, MD, PhD

    The Maslah Saul, MD, Professor and Professor, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsDr. Fisher is interested in clincal, laboratory and translational aspects of epilepsy research. Prior work has included: electrical deep brain stimulation for epilepsy, studied in laboratory models and clinical trials; drug delivery to a seizure focus; mechanisms of absence epilepsy studied with in vitro slices of brain thalamus; hyperthermic seizures; diagnosis and treatment of non-epileptic seizures, the post-ictal state; driving and epilepsy; new antiepileptic drugs; surgery for epilepsy.

  • Paul George, MD, PhD

    Paul George, MD, PhD

    Associate Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsCONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
    We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.

    BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
    The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.

    APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
    The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes.

  • Pejman Ghanouni, MD, PhD

    Pejman Ghanouni, MD, PhD

    Associate Professor of Radiology (General Radiology) and, by courtesy, of Neurosurgery, of Obstetrics and Gynecology and of Urology

    BioDr. Ghanouni is a board-certified, fellowship-trained diagnostic radiologist with Stanford Health Care Radiology. He is an associate professor in the Department of Radiology, Division of Body MRI at Stanford University School of Medicine, and by courtesy, of Urology, of Neurosurgery, and of Obstetrics and Gynecology.

    Dr. Ghanouni is the director of the Stanford Health Care Minimally Invasive MR Interventional Center (MIMRIC) and the Focused Ultrasound Center of Excellence. He is also chief of the Division of Body MRI at Stanford University School of Medicine.

    Dr. Ghanouni is recognized around the world for his extensive expertise in using advanced imaging to diagnose, manage, and treat a wide range of conditions and disorders. As a renowned leader in diagnostic and MRI-guided interventional radiology, Dr. Ghanouni creates a customized care plan for each of his patients.

    Dr. Ghanouni’s research interests include the latest advances in MR-guided focused ultrasound techniques to treat essential tremor, Parkinson’s disease, prostate cancer, bone tumors, desmoid tumors, and uterine fibroids. An experienced physician-scientist, Dr. Ghanouni has collaboratively led clinical trials and research initiatives that explore treatments for epilepsy, pancreatic cancer, and several types of tumors. Through these clinical trials, Dr. Ghanouni has helped secure FDA approval for many MR-guided focused ultrasound treatments.

    His articles have been published in dozens of peer-reviewed medical journals, including Lancet Oncology, Neurology, Investigative Radiology, European Radiology, Journal of Magnetic Resonance Imaging, Journal of Neurosurgery, New England Journal of Medicine, and Radiology. Dr. Ghanouni has been invited to speak at conferences and symposiums all over the nation and the world, including in Rome, Italy; Tel Aviv, Israel; and Riyadh, Saudi Arabia. He is widely regarded for his groundbreaking research as well as his clinical expertise.

    Dr. Ghanouni is a member of several professional organizations, including the International Society for Magnetic Resonance in Medicine, the International Society for Therapeutic Ultrasound, and the European Focused Ultrasound Society.