School of Medicine
Showing 101-120 of 539 Results
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Dr. Qiwen Deng
Postdoctoral Scholar, Pathology
BioHow fibroblasts participate in the organ fibrosis and whether targeting fibroblasts is a good strategy to reverse fibrosis is still a mystery. We have identified two important immune checkpoints, CD47 and PD-L1, are highly expressed in fibroblasts and blocking CD47 and PD-L1 reversed lung fibrosis. This is a prove of concept that targeting immune regulatory pathways could be an effective therapeutic approach to treat fibrotic diseases. In addition to identifying novel targets for the treatment of fibrosis, I am also interested in the crosstalk between fibroblasts and innate immune cells in the development of fibrosis. Combined with cutting-edge NGS approaches including single cell sequencing, spatial transcriptomics and high-dimensional CyTOF technique, we have identified several potential targets and characterized immune cells landscape in lung fibrosis. In the long run, I will focus on the validation of these targets. Specifically, I will apply gain- and loss-function approaches to investigate their role in fibrosis in vitro and in vivo.
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Dylan Dodd
Assistant Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsHarnessing the gut microbiome to treat human disease.
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Fei Dong
Associate Professor of Pathology
BioDr. Dong is the Associate Director of Molecular Pathology at Stanford Health Care. His clinical interests include the implementation and interpretation of laboratory developed tests in diagnosis and patient care. Previous accomplishments include the development of novel bioinformatics algorithms to infer microsatellite instability and allogeneic contamination from cancer sequencing data. Before arriving at Stanford, Dr. Dong was on faculty at Brigham and Women’s Hospital/Harvard Medical School for nine years, where he established a track record in education and mentorship and was the recipient of both the Anatomic Pathology and Clinical Pathology resident teaching awards. Dr. Dong has served on national/international committees for the Association for Molecular Pathology, the Clinical and Laboratory Standards Institute, and the College of American Pathologists and serves on the editorial boards of multiple academic journals, including the Archives of Pathology and Laboratory Medicine, the Journal of Molecular Diagnostics, and Modern Pathology.
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Alex Edwin
Life Science Research Professional 1, Pathology - Montine Lab
BioAlex received his bachelor's degree in neuroscience from Santa Clara University. He also minored in Spanish and Biology. During his time there, he studied fMRI data to identify patterns of resting-state functional brain connectivity in individuals with Autism Spectrum Disorder. Currently, he utilizes hippocampal slice cultures, cell cultures, and biochemical assays to screen small molecule drug compounds. His research is conducted with hopes to identify novel therapeutics for Alzheimer's disease, Parkinson's disease, and X-linked creatine deficiency.
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Ifeanyichukwu Emmanuel Eke
Postdoctoral Scholar, Pathology
BioI am a chemical biologist with a broad interest in defining the mechanisms-of-action of novel compounds that can be used as potential drugs or diagnostic probes for different bacterial and viral infections. In addition to my flair for research, I am passionate about teaching, mentorship, leadership, and entrepreneurship.
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Lawrence Eng
Professor (Research) of Pathology, Emeritus
Current Research and Scholarly InterestsAstrocytes make up a substantial proportion of the central nervous system (CNS) and participate in a variety of important physiologic and pathologic processes. They are characterized by vigorous response to diverse neurologic insults.
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Edgar Engleman
Professor of Pathology and of Medicine (Immunology and Rheumatology)
Current Research and Scholarly InterestsDendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.
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Dean W. Felsher
Professor of Medicine (Oncology) and of Pathology
Current Research and Scholarly InterestsMy laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.
