School of Medicine


Showing 681-690 of 896 Results

  • David Rosenthal

    David Rosenthal

    Professor of Pediatrics (Pediatric Cardiology)

    Current Research and Scholarly InterestsResearch interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.

  • Bernard Roth

    Bernard Roth

    Professor of Mechanical Engineering, Emeritus

    BioRoth is one of the founders of the Hasso Plattner Institute of Design at Stanford (the d.school) and is active in its development: currently, he serves as Academic Director. His design interests include organizing and presenting workshops on creativity, group interactions, and the problem solving process. Formerly he researched the kinematics, dynamics, control, and design of computer controlled mechanical devices. In kinematics, he studied the mathematical theory of rigid body motions and its application to the design of machines.

  • Stephen J. Roth

    Stephen J. Roth

    Professor of Pediatrics (Cardiology)

    Current Research and Scholarly InterestsRandomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
    Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
    A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.

  • Christopher John Russell

    Christopher John Russell

    Associate Professor of Pediatrics (Hospital Medicine)

    BioDr. Russell is an Associate Professor of Pediatrics in the Division of Pediatric Hospital Medicine and a board-certified academic pediatric hospitalist at Lucile Packard Children’s Hospital. His clinical responsibilities include caring for children hospitalized for a variety of illnesses. His research focuses on developing evidence-based care for hospitalized children with medical complexity, including acute respiratory infections (such as pneumonia and bacterial tracheitis). His research efforts have been recognized through receipt of the University of Southern California’s Clinical and Translational Science Institute’s KL2 Mentored Research Career Development Award (2014-16), the Academic Pediatric Association’s Young Investigator Award (2015-16), the NIH Loan Repayment Program (2017-2021) and a large grant from the Gerber Foundation (2020-2022). In August 2021, he received a five-year R01 award from the Agency for Healthcare Research and Quality to study bacterial respiratory infections in child with tracheostomy. Outside of his clinical and research responsibilities, Dr. Russell focuses on research mentorship of medical students, pediatric residents, and pediatric hospital medicine fellows as well as improving representation of underrepresented minorities in medicine throughout the continuum of physician training. Dr. Russell is the chair of the Academic Pediatric Association’s Membership, Diversity, and Inclusion Committee and is on the Executive Committee for the Pediatric Research in Inpatient Settings research network. Dr. Russell is active in the AAP and currently serves as an Associate Editor for the journal Hospital Pediatrics.

  • Mirabela Rusu

    Mirabela Rusu

    Assistant Professor of Radiology (Integrative Biomedical Imaging Informatics) and, by courtesy, of Urology and of Biomedical Data Science

    Current Research and Scholarly InterestsDr. Mirabela Rusu focuses on developing analytic methods for biomedical data integration, with a particular interest in radiology-pathology fusion. Such integrative methods may be applied to create comprehensive multi-scale representations of biomedical processes and pathological conditions, thus enabling their in-depth characterization.

  • Brian Rutt

    Brian Rutt

    Professor of Radiology (Radiological Sciences Lab), Emeritus

    Current Research and Scholarly InterestsMy research interests center on MRI research, including high-field and high-resolution MRI technology development as well as applications of advanced MRI techniques to studying the brain, cardiovascular system and cancer.

  • maura ruzhnikov

    maura ruzhnikov

    Member, Maternal & Child Health Research Institute (MCHRI)

    BioChild neurologist and medical geneticist focusing on the diagnosis and management of rare neurologic disorders. Specific interests are in genetic epilepsy syndromes, childhood neurodegenerative and neurometabolic diseases and undiagnosed suspected genetic conditions.

  • Raya Saab

    Raya Saab

    Lindhard Family Professor of Pediatric Cancer Biology

    BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
    Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
    We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
    Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting.

  • Debra Safer

    Debra Safer

    Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)

    Current Research and Scholarly InterestsPrimary research interests include the nature and treatment of eating disorders
    (particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery.

  • Julien Sage

    Julien Sage

    Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
    On Partial Leave from 04/22/2024 To 06/24/2024

    Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.