School of Medicine
Showing 121-139 of 139 Results
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Peter Tass
Professor of Neurosurgery
BioDr. Peter Tass investigates and develops neuromodulation techniques for understanding and treating neurologic conditions such as Parkinson’s disease, epilepsy, dysfunction following stroke and tinnitus. He creates invasive and non-invasive therapeutic procedures by means of comprehensive computational neuroscience studies and advanced data analysis techniques. The computational neuroscience studies guide experiments that use clinical electrophysiology measures, such as high density EEG recordings and MRI imaging, and various outcome measures. He has pioneered a neuromodulation approach based on thorough computational modelling that employs dynamic self-organization, plasticity and other neuromodulation principles to produce sustained effects after stimulation. To investigate stimulation effects and disease-related brain activity, he focuses on the development of stimulation methods that cause a sustained neural desynchronization by an unlearning of abnormal synaptic interactions. He also performs and contributes to pre-clinical and clinical research in related areas.
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Nicholas Telischak
Clinical Associate Professor, Radiology
Clinical Associate Professor (By courtesy), NeurosurgeryBioDr. Nick Telischak is a neurointerventional surgeon (neurointerventional radiologist) who specializes in the diagnosis and treatment of stroke, brain aneurysms, brain arteriovenous malformations, brain and spinal dural arteriovenous fistulae, carotid artery stenosis, vertebral body compression fractures, spinal metastases, axial back pain, and congenital vascular malformations. Dr. Telischak treats all of these conditions using minimally-invasive, image-guided procedures and state-of-the-art technology.
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Suzanne Tharin
Associate Professor of Neurosurgery
Current Research and Scholarly InterestsThe long-term goal of my research is the repair of damaged corticospinal circuitry. Therapeutic regeneration strategies will be informed by an understanding both of corticospinal motor neuron (CSMN) development and of events occurring in CSMN in the setting of spinal cord injury. MicroRNAs are small, non-coding RNAs that regulate the expression of “suites” of genes. The work in my lab seeks to identify microRNA controls over CSMN development and over the CSMN response to spinal cord injury.
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Reena Thomas, MD PhD
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), NeurosurgeryCurrent Research and Scholarly Interests-Neuro Oncology Immunotherapy
-Health Equity
-Medical Education -
Zachary David Threlkeld
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), NeurosurgeryBioDr. Threlkeld cares for critically ill patients with acute neurologic illness, including traumatic brain injury, stroke, intracerebral hemorrhage, and epilepsy. He completed his residency training in neurology at the University of California, San Francisco, and joined the Stanford Neurocritical Care program after completing fellowship training in neurocritical care at Massachusetts General Hospital and Brigham and Women’s Hospital in Boston. He has a particular clinical and research interest in traumatic brain injury. His research uses advanced imaging modalities like functional magnetic resonance imaging (fMRI) to better understand disorders of consciousness.
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Maxine Umeh Garcia
Instructor, Neurosurgery
BioMaxine was born and raised in Sacramento, CA and transferred to UC Merced in 2007 after attending a community college for 2 years. She received her B.S. in Developmental Biology with a minor in Psychology in 2010. During the last year of her undergrad, Maxine was invited to do research in the lab of Dr. Michael Cleary, studying nervous system development. Because of this research experience, Maxine decided to stay at UC Merced to pursue her Master’s in Quantitative and Systems Biology, graduating in 2013. Immediately after graduating, she started her Ph.D. at UC Davis, where her research centered on triple negative breast cancer – a type of breast cancer that has a high incidence in Black and African women.
After completing her PhD in Biochemistry, Molecular, Cell and Developmental Biology with an emphasis in Translational Research in 2019, Maxine became a postdoctoral fellow at Stanford University in the department of Neurosurgery. Dr. Umeh Garcia’s research focuses on breast cancers that metastasize (or travel) to the brain. Maxine was recently promoted to an instructor position in her department after receiving a major career development award from the National Cancer Institute (K99/R00), which will fund the remainder of her postdoctoral research and provide 3 years of funding for Maxine to establish her own independent research lab. Using her background in bench research, informatics, and translational research, Dr. Umeh Garcia hopes to bring together biologists, data scientists, and clinicians to make important advances in breast cancer diagnosis and treatment. Additionally, as a women and underrepresented minority, Dr. Umeh Garcia is keenly interested in mentoring women and underrepresented students, and in developing novel strategic approaches to increasing diversity in biomedical sciences and academic research. -
Anand Veeravagu
Associate Professor of Neurosurgery and, by courtesy, of Orthopaedic Surgery
Current Research and Scholarly InterestsThe focus of my laboratory is to utilize precision medicine techniques to improve the diagnosis and treatment of neurologic conditions. From traumatic brain injury to spinal scoliosis, the ability to capture detailed data regarding clinical symptoms and treatment outcomes has empowered us to do better for patients. Utilize data to do better for patients, that’s what we do.
Stanford Neurosurgical Ai and Machine Learning Lab
http://med.stanford.edu/neurosurgery/research/AILab.html -
Chitra Venkatasubramanian, MBBS, MD, MSc, FNCS
Clinical Professor, Neurology & Neurological Sciences
Clinical Professor (By courtesy), NeurosurgeryCurrent Research and Scholarly InterestsI am interested in the study of the radiological characteristics and temporal profile of edema/ tissue injury in the perihematomal area around spontaneous intracerebral hemorrhage. I am also interested in developing protocols for emergent reversal of anticoagulation in a life-threatening hemorrhage situation.
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Hannes Vogel MD
Professor of Pathology and of Pediatrics (Pediatric Genetics) and, by courtesy, of Neurosurgery, Neurology and of Comparative Medicine
Current Research and Scholarly InterestsMy research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology.
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Xinnan Wang
Associate Professor of Neurosurgery
Current Research and Scholarly InterestsMechanisms underlying mitochondrial dynamics and function, and their implications in neurological disorders.
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Thomas J. Wilson
Clinical Associate Professor, Neurosurgery
BioDr. Thomas J. Wilson was born in Omaha, Nebraska. He attended the University of Nebraska College of Medicine, earning his MD with highest distinction. While a medical student, he was awarded a Howard Hughes Medical Institute Research Training Fellowship and spent a year in the lab of Dr. Rakesh Singh at the University of Nebraska. He was also elected to the prestigious Alpha Omega Alpha Honor Medical Society. He completed his residency training in neurological surgery at the University of Michigan and was mentored by Dr. Lynda Yang and Dr. John McGillicuddy in peripheral nerve surgery. Following his residency, he completed a fellowship in peripheral nerve surgery at the Mayo Clinic in Rochester, Minnesota, working with Dr. Robert Spinner. He is now Clinical Associate Professor and Co-Director of the Center for Peripheral Nerve Surgery at Stanford University. He also holds a Master of Public Health (MPH) degree from the Bloomberg School of Public Health at Johns Hopkins University, with focused certificates in Clinical Trials and Health Finance and Management. His research interests include peripheral nerve outcomes research, clinical trials advancing options for patients with peripheral nerve pathologies and spinal cord injuries, and translational research focused on improved imaging techniques to assist in diagnosing nerve pain and other peripheral nerve conditions. His clinical practice encompasses the treatment of all peripheral nerve pathologies, including entrapment neuropathies, nerve tumors, nerve injuries (including brachial plexus injuries, upper and lower extremity nerve injuries), and nerve pain. Dr. Wilson enjoys working in multi-disciplinary teams to solve complex problems of the peripheral nervous system. His wife, Dr. Monique Wilson, is a practicing dermatologist in the Bay Area.
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Albert J. Wong, M.D.
Professor of Neurosurgery
Current Research and Scholarly InterestsOur goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective.
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Moss Zhao
Instructor, Neurosurgery
BioDr. Moss Zhao is an Instructor at Department of Neurosurgery, Stanford University. He develops cutting-edge and clinically viable imaging technologies to improve the diagnosis and treatment of cerebrovascular diseases across the lifespan. His specific areas of expertise include physiological modeling, arterial spin labeling, Bayesian inference, PET/MRI, and artificial intelligence. His scientific contributions could significantly improve the early detection of strokes and dementia as well as enrich the knowledge of brain development in the first two decades of life.
Dr. Zhao received his DPhil at St Cross College of University of Oxford under the supervision of Prof. Michael Chappell. As an alumni mentor, he supports the career development of students of his alma mater. Since 2016, he has presented his work to more than 3000 delegates at international conferences and held leadership positions in professional societies. His research and teaching are supported by the American Heart Association, the National Institutes of Health, and the European Cooperation in Science and Technology. -
Quan Zhou
Instructor, Neurosurgery
Current Research and Scholarly InterestsCurrent Research Focus: molecular targeted theranostic imaging of brain tumor and enhanced drug delivery
Areas of Insterests: molecular imaging, theranostics, fluorescence-guided surgery, brain tumor, drug delivery
Dr. Zhou has made substantial contributions to the growing biomedical research field of Molecular Imaging. Molecular imaging emerged in the mid twentieth century as a highly specialized discipline at the intersection of molecular biology and in vivo imaging, focusing on imaging molecules of medical interest within intact living subjects. Dr. Zhou’s research addresses some of the nation’s most pressing issues related to the development of effective approaches for accurate detection of human diseases and improving their treatment outcome. Her innovations in molecular imaging technology enables the visualization, characterization, and quantification of biologic processes taking place at the cellular and subcellular levels. The multiple and numerous potentialities of Quan’s work are applicable to the diagnosis of diseases such as cancer, neurological and cardiovascular diseases. Her strong education background in biological sciences and biomedical engineering followed by postdoctoral training in translational and clinical research have helped her develop multiple disease-specific molecular probes and imaging strategies for early cancer diagnosis, image-guided surgery, therapeutic delivery prediction and at-risk cardiovascular plaque detection. Her research also contributes to improving the treatment of these disorders by testing and optimizing the execution of new interventions. Her work is expected to have a major economic impact due to earlier disease detection and personalized therapy.
Dr. Zhou’s research has led to emergence of novel solutions and opportunities, in particular, for molecular imaging of cancer and other diseases, for discovering, leveraging and integration of cancer biomarker and tumor microenvironment information, and for novel approaches to acquire real-time high-resolution contrast enhanced visualization of tumor margin and optimization based on imaging depth, quality and speed. Dr. Zhou has been able to formulate the involved clinical and biological problems into biomedical engineering frameworks and find ways to exploit a variety of modern techniques and approaches from photoacoustic imaging, fluorescence-guided surgery, micro-electromechanical systems and therapeutic delivery strategies in developing elegant and effective solutions. Her work in the Neurosurgery Department and Molecular Imaging Program at Stanford involves research related to developing tumor-specific molecular probes, advanced imaging methods and therapeutic delivery systems for adult and pediatric patients with malignant brain cancers to improve margin detection, enhance resection accuracy, and improve treatment outcome. -
J. Bradley Zuchero
Assistant Professor of Neurosurgery
Current Research and Scholarly InterestsGlia are a frontier of neuroscience, and overwhelming evidence from the last decade shows that they are essential regulators of all aspects of the nervous system. The Zuchero Lab aims to uncover how glial cells regulate neural development and how their dysfunction contributes to diseases like multiple sclerosis (MS) and in injuries like stroke.
Although glia represent more than half of the cells in the human brain, fundamental questions remain to be answered. How do glia develop their highly specialized morphologies and interact with neurons to powerfully control form and function of the nervous system? How is this disrupted in neurodegenerative diseases and after injury? By bringing cutting-edge cell biology techniques to the study of glia, we aim to uncover how glia help sculpt and regulate the nervous system and test their potential as novel, untapped therapeutic targets for disease and injury.
We are particularly interested in myelin, the insulating sheath around neuronal axons that is lost in diseases like MS. How do oligodendrocytes- the glial cell that produces myelin in the central nervous system- form and remodel myelin, and why do they fail to regenerate myelin in disease? Our current projects aim to use cell biology and neuroscience approaches to answer these fundamental questions. Ultimately we hope our work will lead to much-needed therapies to promote remyelination in patients. -
Corinna Zygourakis, MD
Assistant Professor of Neurosurgery
Current Research and Scholarly InterestsMy goal is to translate research into real-world action and decision-making so that my work can impact patients and the institutions in which they receive care. With a research focus on healthcare cost and quality of care, I approach neurosurgery in a unique way—one that applies business operations, economics, and healthcare delivery principles to our field. I have pursued formal LEAN business training, and believe in the importance of working together with other departments and administrators, as well as physicians and surgeons on the hospital and national level, to effect change. During my residency, I developed and led a multi-departmental prospective study at UCSF called OR SCORE (OR Surgical Cost Reduction Project) that brought together surgeons from the neurosurgery, orthopedics and ENT departments with nurses and administrators. OR SCORE successfully reduced surgical supply costs by nearly one million dollars in its first year by providing >60 surgeons with price transparency scorecards. This work led to a first-author publication in JAMA Surgery, but more importantly, set the foundation for further quality improvement and cost reduction efforts across the UCSF hospital system.
A volunteer neurosurgical mission trip to Guadalajara, Mexico, where limited resources create an OR environment that is strikingly more frugal than the U.S., inspired me to lead another project aimed at quantifying and reducing operating room waste at UCSF. I have also conducted research looking at the safety and outcomes of overlapping surgery, as well as several projects to define the factors underlying variation in cost for neurosurgical care using UCSF’s hospital data and national databases like the National Inpatient Sample, Vizient (formerly known as University Health Consortium), and Medicare.
As a clinical fellow at Johns Hopkins, I continued and expanded these research efforts. I designed and implemented an Enhanced Recovery after Surgery (ERAS) protocol at the Johns Hopkins Bayview hospital. This protocol standardized care for our spine patients, emphasizing pre-operative rehabilitation, psychiatric and nutritional assessments, and smoking cessation, as well as intra- and post-operative multi-modal pain therapy, early mobilization, and standardized antibiotic and bowel regimens. I also collaborated with engineers in the Johns Hopkins Carnegie Center for Surgical Innovation to develop better algorithms for intra-operative CT imaging, and provided assistance with operations to a basic science study looking at the role of cerebrospinal fluid drainage and duraplasty in a porcine model of spinal cord injury.
At Stanford, I am building a research group focused on: (1) perfecting paradigms for delivery of high-end technology in spinal care, including robotics and navigation, (2) implementing cost and quality strategies in large healthcare systems, and (3) computational analysis of big-data to effect real-time risk stratification and decision making in spine surgery. I'm excited to collaborate with my peers across surgical and medical departments, as well as business and engineering colleagues.
