School of Medicine
Showing 71-80 of 122 Results
-
Lucy Erin O'Brien
Associate Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMany adult organs tune their functional capacity to variable levels of physiologic demand. Adaptive organ resizing breaks the allometry of the body plan that was established during development, suggesting that it occurs through different mechanisms. Emerging evidence points to stem cells as key players in these mechanisms. We use the Drosophila midgut, a stem-cell based organ analogous to the vertebrate small intestine, as a simple model to uncover the rules that govern adaptive remodeling.
-
Tino Pleiner
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsThe Pleiner lab combines mechanistic cell biology, structural biochemistry and protein engineering to dissect the pathways and molecular machines that mature human membrane proteins to a fully functional state. We also develop alpaca-derived and synthetic nanobodies as tools to modulate intracellular pathways that globally regulate protein homeostasis in health and disease.