SLAC National Accelerator Laboratory
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Britt Hedman
Professor of Photon Science
BioHedman’s research program is focused on the development and applications of x-ray absorption and emission spectroscopies using synchrotron radiation, with a scientific emphasis primarily on study of the electronic and structural aspects of metal ion active sites in bioinorganic and biological systems. A common theme is to investigate how structure at molecular and macromolecular levels relates to function.
A major long-term focus has been the active site of the enzyme nitrogenase, and the various nitrogenase metal clusters, including elucidating the electronic and geometric structure of those that are formed and changed along their biosynthetic pathways. Other systems of systematic studies include iron-sulfur cluster containing enzymes, blue and multi-copper proteins, heme-copper oxidases, and iron-containing oxidases. Methods developments include x-ray absorption spectroscopy (edge and extended fine structure - or EXAFS), including the application of multiple-scattering analysis in EXAFS studies of metal clusters relevant to bioinorganic systems, the development of methodology for polarized single crystal x-ray absorption spectroscopy, and methodology and instrumentation development for soft- through hard-energy XAS.
Hedman received her B.S and B.A. in Chemistry, M.Sc. in Inorganic Chemistry, and Ph.D. in Chemistry from the University of Umeå, Sweden. She was Assistant Professor (equivalent) in Inorganic Chemistry at the University of Umeå before coming to Stanford, initially as Senior Academic Scientific Staff, followed by appointed as Professor (Research) in 2002, and Professor of Photon Science in 2007.
