Stanford University
Showing 81-90 of 371 Results
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Julie Parsonnet
George DeForest Barnett Professor of Medicine, Emerita
Current Research and Scholarly InterestsI am an infectious diseases epidemiologist who has done large field studies in both the US and developing countries. We research the long-term consequences of chronic interactions between the human host and the microbial world. My lab has done fundamental work establishing the role of H. pylori in causing disease and understanding its epidemiology. Currently, our research dissects how and when children first encounter microbes and the long term effects of these exposures on health.
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Sonia Partap
Clinical Professor, Pediatric Neurology
Clinical Professor (By courtesy), Neurosurgery
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsMy research interests involve the epidemiology, treatment and diagnosis of pediatric and young adult brain tumors. I am also interested in long-term neurologic effects and designing clinical trials to treat brain and spinal cord tumors.
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Gopanandan Parthasarathy
Clinical Assistant Professor, Medicine - Gastroenterology & Hepatology
BioDr Nandan Parthasarathy is a hepatologist and physician-scientist in the Department of Gastroenterology and Hepatology at Stanford University.
After obtaining his medical degree in JIPMER, India, he completed a 2 year clinical research fellowship at Mayo Clinic, following which he completed his residency training at Cleveland Clinic, and GI and transplant hepatology fellowships at Mayo Clinic. During his fellowship, his research work was focused on exploring the immune mechanisms of liver injury in metabolic dysfunction associated steatohepatitis.
Clinically, he is focused on taking care of patients with MASH, cirrhosis and liver cancer.
His career goal is to study the gut-immune system-liver injury axis in order to bring novel therapeutics from the bench to bedside in patients with liver disease. -
Josef Parvizi, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
BioDr. Parvizi completed his medical internship at Mayo Clinic, neurology training at Harvard, and subspecialty training in clinical neurophysiology and epilepsy at UCLA before joining the Department of Neurology and Neurological Sciences at Stanford in 2007. Dr. Parvizi directs the Stanford Program for Medication Resistant Epilepsies and specializes in surgical treatments of intractable focal epilepsies. Dr. Parvizi is the principal investigator in the Laboratory of Behavioral and Cognitive Neuroscience, where he leads a team of investigators to study the human brain. http://med.stanford.edu/parvizi-lab.html.
Epilepsy patient story: https://www.youtube.com/watch?v=HXy-gXg0t94&t=3s -
Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsI am a physician-scientist, neonatologist, and stem cell biologist whose research focuses on understanding mechanisms of human brain development, neuroinflammation, and neurological injury using patient-derived stem cell models.
I was among the early pioneers of three-dimensional human cortical organoid technologies and contributed to development of foundational protocols for generating region-specific human brain organoids from pluripotent stem cells. My work helped establish the feasibility of modeling human brain development and disease using stem cell-derived tissues and has contributed to the widespread adoption of organoid technologies across neuroscience, regenerative medicine, and translational research.
A major focus of my laboratory is the development of increasingly sophisticated multicellular organoid and assembloid systems that incorporate diverse neuronal and glial populations to model complex human brain circuitry and disease processes. We integrate stem cell biology, organoid engineering, CRISPR-based genome editing, single-cell transcriptomics, epigenomics, high-content imaging, and computational approaches to identify disease mechanisms and therapeutic targets. These technologies have been applied to studies of hypoxic brain injury, 22q11.2 deletion syndrome, Trisomy 21 (Down Syndrome), Trisomy 18, narcolepsy, Alzheimer's and Parkinson's Disease. -
Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program and Senior Fellow, by courtesy, at the Hoover Institution
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Elena Pastorino
Research Fellow, HOOVER RESEARCH
BioElena Pastorino is a research fellow at the Hoover Institution and an affiliated faculty member of the Department of Economics at Stanford University. She holds a Ph.D. from the University of Pennsylvania. Her interests are in the areas of labor economics, macroeconomics, and development economics. Her research focuses on understanding the determinants of wages, job mobility, employment, and consumption, and on evaluating the impact of government policies in both developed and developing countries.
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M Elisabeth Pate-Cornell
Burton J. and DeeDee McMurtry Professor in the School of Engineering and Professor, by courtesy, of Aeronautics and Astronautics
BioDr. Marie-Elisabeth Paté-Cornell is the Burt and Deedee McMurtry Professor in the School of Engineering, and a Professor and Founding Chair of the Department of Management Science and Engineering at Stanford University (2000-2011). Previously, she was the Professor and Chair of the Stanford Department of Industrial Engineering and Engineering Management and an Assistant Professor of Civil Engineering at MIT. Her specialty is engineering risk analysis with application to complex systems (seismic risk, space systems, medical procedures and devices, offshore oil platforms, cyber security, etc.). Her earlier research has focused on the optimization of warning systems and the explicit inclusion of human and organizational factors in the analysis of systems’ failure risks. Her more recent work is on the use of game theory in risk analysis with applications that have included counterterrorism and cyber security.
She is a member of the National Academy of Engineering where she chairs the section of Interdisciplinary Engineering and Special Fields, of the French Académie des Technologies, and of the NASA Advisory Council. She is co-chair of the committee of the National Academies (NASEM) on risk analysis methods for nuclear war and nuclear terrorism. She is a Fellow (and past president) of the Society for Risk Analysis and of the Institute for Operations Research and Management Science. She is the author of more than one hundred publications, with several best paper awards, and the co-editor of a book on Perspectives on Complex Global Problems (2016). She was a member of the Board of Advisors of the Naval Postgraduate School, which she chaired from 2004 to 2006, and of the Navy War College. Dr. Paté-Cornell was also a member of the President’s (Foreign) Intelligence Advisory Board (2001-2008), of the board of the Aerospace Corporation (2004-2013) of Draper Laboratory (2009-2016), and of InQtel (2006-2017). She was awarded the Frank Ramsey Medal of the Decision Analysis Society, the 2021 IEEE Ramo medal in Systems Engineering and Science, and the 2022 PICMET Award for Leadership in Technology Management. She is a Fellow (and past president) of the Society for Risk Analysis and of the Institute for Management Science and Operations Research, and a Distinguished Vising Scientist of the NASA Jet Propulsion Laboratory. She is the author of more than one hundred publications, for which she got several best paper awards, and the co-editor of a book on Perspectives on Complex Global Problems (2016). She holds a BS in Mathematics and Physics, Marseille (France), an Engineering degree (Applied Math/CS) from the Institut Polytechnique de Grenoble (France), an MS in Operations Research and a PhD in Engineering-Economic Systems, both from Stanford University.
She and her late husband, Dr. Allin Cornell had two children, Philip Cornell (born 1981) and Ariane Cornell (1984). She is married to Admiral James O. Ellis Jr. (US Navy, Ret.).
