Stanford University
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Yunkyeong Lee
Postdoctoral Scholar, Endocrinology and Metabolism
BioYun is a postdoctoral research scholar in the Translational Genomics of Diabetes Laboratory under the mentorship of Dr. Anna Gloyn. Since joining the lab in August 2022, she has been investigating type 2 diabetes (T2D) susceptible genes and their molecular mechanisms in pancreatic β-cell dysfunction and the development of T2D. Her primary focus is on how T2D effector transcripts alter autophagy/mitophagy pathways in human pancreatic β-cells, contributing to β-cell failure, mitochondrial dysfunction, and T2D pathology. She also investigated the impact of genetic mutations underlying neonatal diabetes using CRISPR HDR knockin genome editing in human induced pluripotent stem cell (hiPSC) models and their derivatives.
During her PhD, she explored the role of an epigenetic regulator and its molecular machinery in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD). In parallel, she studied the interplay between endoplasmic reticulum (ER) stress-mediated unfolded protein response (UPR) signalling and autophagy, and examined how these processes are modulated by bioactive plant extracts in various cellular contexts.
She is particularly interested in exploring inter-organ communication, such as pancreas-liver crosstalk, and how these interactions influence systemic metabolism and contribute to the onset and progression of T2D, along with its complications. Her long-term research goal is to advance our understanding of the cellular and molecular mechanisms driving T2D and to identify novel therapeutic targets and strategies. -
Paul Lendway
Postdoctoral Scholar, Political Science
BioThe norms and rules that comprise American democracy are eroding. Why? What are the consequences of this trend? And what can be done to address this issue? My research program aims to address these questions. One stream of my research investigates how various forms of political communication (i.e., sermon rhetoric, populist appeals, etc.) shape political preferences. Another strand of my research probes the role of information (i.e., information about social movements or inequality) in structuring public opinion and policy preferences. A final line of my research explores solutions to mass polarization. This includes a project that tests Americans' willingness to compromise on a series of multi-dimensional policy tradeoffs (i.e., a conservative immigration policy and a liberal abortion policy, etc.).
My research is published or forthcoming in Political Behavior, American Politics Research, Research and Politics, the Journal of Conflict Resolution, and Environmental Politics. My co-authored paper that meta-analyzes the literature on populist appeals and vote choice has a R&R at the American Journal of Political Science. I have presented my research at a wide range of organizations, including the American Political Science Association, Harvard University, Princeton University, and Yale University. Funding for my research has been provided by the University of Pennsylvania, Yale University, and other organizations.
