Stanford University
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Cynthia Khoo
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Khoo serves as the Associate Program Director of Career Development for the Stanford Anesthesia Residency and Co-Director of the Division of Global Health Equity. In her residency role, she leads the Anesthesiology Leadership Pathways at Stanford (ALPS), a comprehensive mentorship initiative spanning advocacy, research, community engagement, global health, innovation, medical education and quality improvement.
A graduate of the University of Pennsylvania’s MD-PhD program, Dr. Khoo completed her residency and regional anesthesia fellowship at Stanford. Her global health work focuses on promoting safe, equitable perioperative care through high-tech education, including immersive reality simulations for crisis management in Tanzania and Guyana. She supports bi-directional partnerships that facilitate resident rotations and host international scholars at Stanford. Her current research focuses on enhancing clinical research quality in low-resource settings across Rwanda, Vietnam, Guyana, and Tanzania. Dr. Khoo specializes clinically in regional, orthopedic, and thoracic anesthesia. -
Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine.
