Stanford University
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Aaron Frank
Affiliate, Department Funds
Resident in MedicineBioAaron Frank, MD is an Internal Medicine Resident Physician at Stanford Healthcare. He graduated with distinction in medical education innovation and was inducted into the AOA Medical Honor Society at UC Irvine School of Medicine. A prior television producer who worked with CNN, ABC, History, Discovery, HGTV, Food Network, Travel Channel, NBC, Vice, he is committed to innovate groundbreaking ways of incorporating new technology into medical education. He also is a co-executive director and co-Founder of Sewing For Lives, a 501(c)(3) nonprofit organization, and led a group of 2,500 worldwide volunteers in making over 250,000 masks for healthcare workers, police and fire departments, teachers, and students throughout the COVID-19 pandemic. At UC Irvine, he created over 50 physical exam instructional videos viewed by medical students and residents. In addition, he is a member of The Empathy Project at NYU with Jon LaPook, MD, Chief Medical Correspondent for CBS news.
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Curtis Frank
W. M. Keck, Sr. Professor in Engineering, Emeritus
BioThe properties of ultrathin polymer films are often different from their bulk counterparts. We use spin casting, Langmuir-Blodgett deposition, and surface grafting to fabricate ultrathin films in the range of 100 to 1000 Angstroms thick. Macromolecular amphiphiles are examined at the air-water interface by surface pressure, Brewster angle microscopy, and interfacial shear measurements and on solid substrates by atomic force microscopy, FTIR, and ellipsometry. A vapor-deposition-polymerization process has been developed for covalent grafting of poly(amino acids) from solid substrates. FTIR measurements permit study of secondary structures (right and left-handed alpha helices, parallel and anti-parallel beta sheets) as a function of temperature and environment.
A broadly interdisciplinary collaboration has been established with the Department of Ophthalmology in the Stanford School of Medicine. We have designed and synthesized a fully interpenetrating network of two different hydrogel materials that have properties consistent with application as a substitute for the human cornea: high water swellability up to 85%,tensile strength comparable to the cornea, high glucose permeability comparable to the cornea, and sufficient tear strength to permit suturing. We have developed a technique for surface modification with adhesion peptides that allows binding of collagen and subsequent growth of epithelial cells. Broad questions on the relationships among molecular structure, processing protocol, and biomedical device application are being pursued.
