Stanford University
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M Bruce MacIver
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine, Emeritus
Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.
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Crystal Mackall
Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.
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Kristen Klepac MacKenzie, MD
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Kristen MacKenzie is a Clinical Assistant Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine. Dr. MacKenzie graduated AOA with a MD from UCSF and then completed her anesthesia residency and pain medicine fellowships at Stanford. She works at the Stanford Pain Management Center with specialty interests in chronic pelvic and abdominal pain, as well as peripartum pain. She is the co-director for the Stanford Pelvic Pain Program as well as part of the Stanford Pelvic Health Center for interdisciplinary, multimodal care.
She completed a Stanford Faculty Medical Humanities Fellowship, focusing on the role of communication and the arts in modern medicine. She serves as the co-director for the Women's Sexual Dysfunction Case Conference. She is active in the American Academy of Pain Medicine (AAPM), and for the 2026-2027 year is serving as the Women in Pain Medicine Shared Interest Group (SIG) Co-Chair as well as a Director-at-large.
Outside of work, she enjoys being outdoors in the Bay Area, trail running, and spending time with her husband and two boys.
Clinical focus:
Pelvic pain, due to multiple causes including:
Dyspareunia
Painful Bladder Syndrome/ Interstitial cystitis/ Dysuria
Endometriosis
Fibroids
Pelvis Congestion Syndrome
Pelvic Floor Dysfunction
Pudendal Nerve Pain
Rectal/Anal Pain
Vulvar Pain/ Vulvodynia/ Vaginismus
Nerve entrapment syndromes, including hernia nerve entrapment
Post-partum and Peri-partum pain
Abdominal pain
Musculoskeletal pain
New Patients: Please have your primary treating provider place a referral to Stanford Pain Clinic and specify Pelvic Pain, Dr. MacKenzie.
