Stanford University


Showing 21-40 of 50 Results

  • Vivek Bhalla, MD

    Vivek Bhalla, MD

    Associate Professor of Medicine (Nephrology)
    On Partial Leave from 03/01/2024 To 08/31/2024

    Current Research and Scholarly InterestsDr. Bhalla's two primary research interests are in the role of the kidney in diabetes and hypertension. We use molecular, biochemical, and transgenic approaches to study: (1) mechanisms diabetic kidney disease disease including the role of the endothelium to regulate inflammation and kidney injury; and (2) regulation of tubular transport of glucose, sodium, and potassium. These latter studies have treatment implications in diabetes, kidney disease, and hypertension.

  • Ami Bhatt

    Ami Bhatt

    Associate Professor of Medicine (Hematology) and of Genetics

    Current Research and Scholarly InterestsThe Bhatt lab is exploring how the microbiota is intertwined with states of health and disease. We apply the most modern genetic tools in an effort to deconvolute the mechanism of human diseases.

  • Y. Katherine Bianco

    Y. Katherine Bianco

    Clinical Professor, Obstetrics & Gynecology - Maternal Fetal Medicine

    BioMy clinical interest in pregnancies complicated with birth defects has led my underlying research interests in genomic abnormalities in the human trophoblast carrying to faulty placentation. The latter began with initial work during K12 and KO8 funding. I took a great interest in the human placenta as it carries potential advantages over other tissues sources: first, this highly metabolically active organ is the potential source of many transcripts. Second, the placenta forms at a very early stage of embryonic development, potentially allowing detection of primary alterations as compared to secondary changes that may mask the underlying causal phenomena. Finally, studying early placentation may provide targets for development of novel molecular approaches, such as up-regulate or down-regulate genes, the protein products of which could potentially serve as molecular surrogates for diagnosis and treatment of pregnancy complication such as miscarriages, pre-eclampsia, pregnancy induced hypertension and intrauterine growth retardation. This work has led to the first Trisomy 21, Trisomy 18, trisomy 13 cell lines established from human placentas making it possible to apply gene editing in the early stages of human trophoblast development.

    As my primary clinical responsibility involves treating patients needing medical care and support through their high risk pregnancies, I am interested in factors that may impact outcomes, such as prenatal screening and diagnosis, maternal heart conditions, labor and delivery management, and safety approaches for the second stage of labor. In investigating length of labor and approaches to shorten the second stage, I have found methods of improving perinatal outcomes in diverse maternal populations.

    With regards to my interest in fetal medicine, I have worked in collaboration with other specialists such as radiologists and pediatric cardiologists utilizing imagining studies to assess and determine successful perinatal care and fetal survival.

  • Sandip Biswal, MD

    Sandip Biswal, MD

    Adjunct Clinical Professor, Radiology

    Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.

  • Richard Bland

    Richard Bland

    Professor (Research) of Pediatrics (Neonatology), Emeritus

    Current Research and Scholarly InterestsOur research focuses on the pathogenesis and treatment of acute and chronic neonatal lung injury and the mechanisms that regulate lung fluid balance and alveolar & pulmonary vascular development after premature birth.

  • Francis Blankenberg

    Francis Blankenberg

    Associate Professor of Radiology (Pediatric Radiology) and, by courtesy, of Pediatrics

    Current Research and Scholarly InterestsStudies on apoptotic cell death in vivo using the H MRS phenomenon.

  • Terrence Blaschke

    Terrence Blaschke

    Professor of Medicine and of Molecular Pharmacology, Emeritus

    Current Research and Scholarly InterestsClinical pharmacology of antiretroviral drugs

    Pharmacokinetic and pharmacodynamic mechanisms of variability in drug response.

    Drug development

  • Helen M. Blau

    Helen M. Blau

    Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.

  • Paul Bollyky

    Paul Bollyky

    Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsChronic bacterial infections are a major health care problem. Our lab is interested in understanding the host and microbial factors that perpetuate chronic infections and in developing novel therapeutic interventions to improve human health.

  • Anna Maria Bombardieri

    Anna Maria Bombardieri

    Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsMy overall research goal is to advance clinical practice by providing anesthesiologists with data to most effectively maintain cerebral blood flow in the perioperative period.
    I am interested in the effect of the autonomic nervous system on cerebral blood flow regulation.
    I intend to combine regional anesthetic techniques and noninvasive bedside cerebral blood flow monitoring to understand the effect of the sympathetic system on cerebral blood flow.
    A secondary goal is to apply this new knowledge to investigate whether cervical sympathetic blocks improve long term neurological outcomes.

  • Bernardo Bonilauri

    Bernardo Bonilauri

    Postdoctoral Scholar, Cardiovascular Institute

    BioI am a highly motivated and devoted scientist, deeply committed to advancing our understanding of the molecular foundations of cardiovascular disease while spearheading innovative therapeutic approaches and drug discovery. As a Postdoctoral Research Fellow at the Stanford Cardiovascular Institute, under the guidance of Dr. Joseph C. Wu, I am privileged to contribute to cutting-edge research. My work spans various disciplines, including multi-omics, molecular and cellular biology, tissue engineering, biochemistry, structural biology, and state-of-the-art imaging technologies. This holistic approach and sharp critical thinking equips me to untangle the complexities of cardiac diseases and innovate novel therapeutic strategies, particularly for rare cardiac conditions such as Transthyretin Cardiac Amyloidosis.

  • Crystal M. Botham, Ph.D.

    Crystal M. Botham, Ph.D.

    Director of Grant Writing Academy & Office of Research Development, Pediatrics

    Current Role at Stanford• Providing individualized grantsmanship assistance to postdoctoral fellows and faculty
    • Editing and critically evaluating grant applications to improve funding potential
    • Interpreting sponsor requirements and providing strategic advice
    • Identifying a diverse portfolio of funding opportunities
    • Designing and facilitating courses to enable postdoctoral fellows to develop competitive Career Development applications
    • Developing and presenting at workshops on grant writing and proposal submission
    • Coordinating completion of subcontracts and large collaborative projects

  • Francesca Briganti

    Francesca Briganti

    Instructor, Cardiovascular Institute

    Current Research and Scholarly InterestsOne gene can lead to the production of many different RNA isoforms via mechanisms such as alternative promoter usage, splicing, and polyadenylation. The functional significance of many of these isoforms, their impact on cell physiology, and their regulation remain mostly controversial. Understanding the functional consequences of transcript heterogeneity will improve our understanding of gene expression regulation, broadening our ability to intervene when mutations that interfere with this regulation cause human disease.
    My goal is to become an independent researcher leading an academic lab that focuses on better understanding human tissue-specific post-transcriptional regulation of gene expression and developing mechanism-based therapeutics. My general strategy is to study the function of regulatory genes and their deregulation in human disease. My specific approach is to understand the molecular mechanisms by which disease-causing mutations alter the gene function and lead to human disease. My hypothesis is that a detailed understanding of the relationship between the gene's molecular function and the disease mechanism will allow the development of first-in-class, personalized therapeutic strategies that target the disease mechanisms rather than manage symptoms independently of disease etiology.