Stanford University
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Romain Lopez
Affiliate, Genetics
BioSince Fall 2021, I am a joint postdoctoral scholar at Stanford University and Genentech Research and Early Development, hosted by Jonathan Pritchard and Aviv Regev. I recently obtained my PhD degree from the department of Electrical Engineering and Computer Sciences at UC Berkeley, advised by Mike Jordan & Nir Yosef. My research interests lie at the intersection of statistics, computation and modeling with a focus on biological applications.
A significant part of my research is driven by building more statistically accurate and faster machine learning software for analyzing single-cell omics data. I developed single-cell Variational Inference (scVI), a flexible model and a scalable inference method for comprehensive analysis of single-cell transcriptomes. I co-developed scvi-tools, an open-source software suite for fully-probabilistic modeling of single-cell multi-omics data. You may learn more about these topics in my guest lecture of the Deep Learning in the Life Sciences class at MIT.
More generally, I am interested in the broader area of ML + Science. Deep generative models provide an appealing and flexible paradigm for learning distributions, but quite some work is needed to fully exploit them as part of a scientific hypothesis testing pipeline (e.g., causality, interpretability, disentanglement, decision-making).
Previously, I worked on counterfactual inference and offline policy learning methods in collaboration with technology companies. In 2018, I visited Le Song at Ant Financial in Hangzhou. In 2019, I visited Inderjit Dhillon at Amazon in Berkeley. Before graduate school, I obtained a MSc in applied mathematics from Ecole polytechnique, Palaiseau in 2016. Additionally, I worked as an intern at the Harvard Medical School with Allon Klein in 2016. I was born and grew up in Bedarieux, France. -
Javier López-Rivera
Bioinformatician, Pediatrics - Gastroenterology
BioDr. López-Rivera is a Bioinformatician in the Rosen Lab at Stanford Medicine Children’s Health Center for IBD and Celiac Disease. He earned his PhD in 2022 from the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. In the Rosen Lab, Dr. López-Rivera focuses on processing, analyzing, and integrating real world patient date with large biological datasets from a number of state-of-the-art high-throughput approaches including transcriptomics, epigenomics, metabolomics, and metagenomics. His work focuses on elucidating the epigenetic and transcriptional changes that underlie epithelial alterations in pediatric Inflammatory Bowel Disease and how these are recapitulated in patient-derived organoids as well as identifying clinical, metabolic, and metagenetic changes associated with patient response to therapy. He also provides bioinformatic and biostatistical analysis support to the various researchers and physician scientists of the Center. In his free time, Dr. López-Rivera enjoys cooking, taking care of his plants, and making ceramics.