Stanford University
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Kristen Klepac MacKenzie, MD
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Kristen MacKenzie is a Clinical Assistant Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine. Dr. MacKenzie graduated AOA with a MD from UCSF and then completed her anesthesia residency and pain medicine fellowships at Stanford. She works at the Stanford Pain Management Center with specialty interests in chronic pelvic and abdominal pain, as well as peripartum pain. She is the co-director for the Stanford Pelvic Pain Program as well as part of the Stanford Pelvic Health Center for interdisciplinary, multimodal care.
She completed a Stanford Faculty Medical Humanities Fellowship, focusing on the role of communication and the arts in modern medicine. She serves as the co-director for the Women's Sexual Dysfunction Case Conference. She is active in the American Academy of Pain Medicine (AAPM), and for the 2026-2027 year is serving as the Women in Pain Medicine Shared Interest Group (SIG) Co-Chair as well as a Director-at-large.
Outside of work, she enjoys being outdoors in the Bay Area, trail running, and spending time with her husband and two boys.
Clinical focus:
Pelvic pain, due to multiple causes including:
Dyspareunia
Painful Bladder Syndrome/ Interstitial cystitis/ Dysuria
Endometriosis
Fibroids
Pelvis Congestion Syndrome
Pelvic Floor Dysfunction
Pudendal Nerve Pain
Rectal/Anal Pain
Vulvar Pain/ Vulvodynia/ Vaginismus
Nerve entrapment syndromes, including hernia nerve entrapment
Post-partum and Peri-partum pain
Abdominal pain
Musculoskeletal pain
New Patients: Please have your primary treating provider place a referral to Stanford Pain Clinic and specify Pelvic Pain, Dr. MacKenzie. -
Sean Mackey, M.D., Ph.D.
Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine (Adult Pain) and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMultiple NIH funded projects to characterize CNS mechanisms of human pain. Comparative effectiveness of cognitive behavioral therapy and chronic pain self-management within the context of opioid reduction (PCORI funded). Single session pain catastrophizing treatment: comparative efficacy & mechanisms (NIH R01). Development and implementation of an open-source learning healthcare system, CHOIR (http://choir/stanford.edu), to optimize pain care and innovative research in real-world patients.
