Stanford University
Showing 11-20 of 82 Results
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Robertson Parkman
Other Teaching Staff-Hourly, Pediatrics - Stem Cell Transplantation
BioMy principal research interests have been the assessment of the immunological consequences of hematopoietic stem cell transplantation including both acute and chronic graft versus host disease and immune reconstitution and the use of hematopoietic stem cell transplantation to treat genetic diseases. My laboratory was the first to suggest that chronic graft versus host disease was an autoimmune disease directed at histocompatibility antigens shared by donors and recipients. The observation leaded to the assessment of the role of thymic dysfunction in the pathogenesis of chronic graft versus host disease. As a pediatric immunologist I have investigated the role of hematopoietic stem cell transplantation initially in the treatment of primary immune deficiency diseases and later the treatment of metabolic diseases, which lead to my involvement in the early gene transfer clinical trials.
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Sonia Partap
Clinical Professor, Pediatric Neurology
Clinical Professor (By courtesy), Neurosurgery
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsMy research interests involve the epidemiology, treatment and diagnosis of pediatric and young adult brain tumors. I am also interested in long-term neurologic effects and designing clinical trials to treat brain and spinal cord tumors.
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Preethy Parthiban
Postdoctoral Scholar, Neonatal and Developmental Medicine
BioMy research centers on how the innate immune system shapes tissue remodeling in health and disease. During my PhD, I uncovered a key role for resident macrophages in driving cardiac fibrosis, identifying a macrophage-derived chemokine that directly activates cardiac fibroblasts. Building on this foundation, my postdoctoral work at Stanford focuses on neutrophil–macrophage crosstalk in disrupted alveolarization in neonatal mice and patients. By integrating cellular, molecular, and translational approaches, I aim to define how innate immune pathways orchestrate extracellular matrix remodeling. Ultimately, my goal is to identify critical therapeutic targets that improve outcomes in ECM-related diseases.
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Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsI am a physician-scientist, neonatologist, and stem cell biologist whose research focuses on understanding mechanisms of human brain development, neuroinflammation, and neurological injury using patient-derived stem cell models.
I was among the early pioneers of three-dimensional human cortical organoid technologies and contributed to development of foundational protocols for generating region-specific human brain organoids from pluripotent stem cells. My work helped establish the feasibility of modeling human brain development and disease using stem cell-derived tissues and has contributed to the widespread adoption of organoid technologies across neuroscience, regenerative medicine, and translational research.
A major focus of my laboratory is the development of increasingly sophisticated multicellular organoid and assembloid systems that incorporate diverse neuronal and glial populations to model complex human brain circuitry and disease processes. We integrate stem cell biology, organoid engineering, CRISPR-based genome editing, single-cell transcriptomics, epigenomics, high-content imaging, and computational approaches to identify disease mechanisms and therapeutic targets. These technologies have been applied to studies of hypoxic brain injury, 22q11.2 deletion syndrome, Trisomy 21 (Down Syndrome), Trisomy 18, narcolepsy, Alzheimer's and Parkinson's Disease. -
Alok Patel
Clinical Associate Professor, Pediatrics
BioAlok Patel is a pediatric hospitalist, medical journalist, on-camera expert, producer, and devotee of creative, engaging science communication tactics. He currently serves as the Faculty Director of Communications for the Department of Pediatrics. Through this role, he helps coordinate creative media strategies for awareness, education, advocacy, recruitment and more.
Dr. Patel has extensive experience in broadcast journalism, on-camera work, script writing, podcast hosting, media consulting, and designing social media campaigns and hopes to lend these skills to his work in public health messaging. He currently works as a pediatric hospitalist within the department of pediatrics at Lucile Packard Children's Hospital.
