Stanford University
Showing 81-90 of 122 Results
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Sharon Pitteri
Professor (Research) of Radiology (Diagnostic Sciences Laboratory)
Current Research and Scholarly InterestsThe Pitteri laboratory is focused on the discovery and validation of proteins that can be used as molecular indicators of risk, diagnosis, progression, and recurrence of cancer. Proteomic technologies, predominantly mass spectrometry, are used to identify proteins in the blood that are differentially regulated and/or post-translationally modified with disease state. Using human plasma samples, tumor tissue, cancer cell lines, and genetically engineered mouse models, the origins of these proteins are being investigated. A major goal of this research is to define novel molecular signatures for breast and ovarian cancers, including particular sub-types of these diseases. This laboratory is also focused on the identification of proteins with expression restricted to the surface of cancer cells which can be used as novel targets for molecular imaging technologies.
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Tino Pleiner
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsThe Pleiner lab combines mechanistic cell biology, structural biochemistry and protein engineering to dissect the pathways and molecular machines that mature human membrane proteins to a fully functional state. We also develop alpaca-derived and synthetic nanobodies as tools to modulate intracellular pathways that globally regulate protein homeostasis in health and disease.
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Sylvia K. Plevritis, PhD
William M. Hume Professor in the School of Medicine, Professor of Biomedical Data Science and of Radiology
Current Research and Scholarly InterestsMy research program focuses on computational modeling of cancer biology and cancer outcomes. My laboratory develops stochastic models of the natural history of cancer based on clinical research data. We estimate population-level outcomes under differing screening and treatment interventions. We also analyze genomic and proteomic cancer data in order to identify molecular networks that are perturbed in cancer initiation and progression and relate these perturbations to patient outcomes.
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Jim Plummer
John M. Fluke Professor of Electrical Engineering, Emeritus
Current Research and Scholarly InterestsGenerally studies the governing physics and fabrication technology of silicon integrated circuits, including the scaling limits of silicon technology, and the application of silicon technology outside traditional integrated circuits, including power switching devices such as IGBTs. Process simulation tools like SUPREM for simulating fabrication. Recent work has focused on wide bandgap semiconductor materials, particularly SiC and GaN, for power control devices.
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Kilian M Pohl
Professor (Research) of Psychiatry and Behavioral Sciences (Major Labs and Incubator) and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsThe foundation of the laboratory is computational science aimed at identifying biomedical phenotypes improving the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders. The biomedical phenotypes are discovered by unbiased, machine learning-based searches across biological, neuroimaging, and neuropsychological data. This data-driven discovery currently supports the adolescent brain research of the NIH-funded National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA). The laboratory also investigates brain patterns specific to alcohol use disorder, depression, and the human immunodeficiency virus (HIV) across the adult age range, and have advanced the understanding of a variety of brain diseases including schizophrenia, Alzheimer’s disease, glioma, and aging.
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Mary Polan
Katharine Dexter McCormick and Stanley McCormick Memorial Professor in the School of Medicine, Emerita
Current Research and Scholarly InterestsDr. Polan's research has centered around ovarian function during both the follicular and luteal phases. Studies of steroidogenesis, LH receptor synthesis, and the involvement of the plasminogen activator system in ovarian events have been performed.
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Russell Poldrack
Albert Ray Lang Professor of Psychology and, by courtesy, of Psychiatry and Behavioral Science
Current Research and Scholarly InterestsOur lab uses the tools of cognitive neuroscience to understand how decision making, executive control, and learning and memory are implemented in the human brain. We also develop neuroinformatics tools and resources to help researchers make better sense of data.
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Jonathan Pollack
Professor of Pathology
Current Research and Scholarly InterestsResearch in the Pollack lab centers on translational genomics, with a focus on prostate diseases. The lab employs next-generation sequencing, single-cell and spatial genomics, gene editing, and human cell/tissue-based modeling to uncover disease mechanisms, biomarkers and therapeutic targets. Current areas of emphasis include benign prostatic hyperplasia, prostate cancer, and rare/neglected cancer types (ameloblastoma, liposarcoma).
