Stanford University
Showing 1-50 of 94 Results
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Cholawat Pacharinsak, DVM, PhD
Associate Professor of Comparative Medicine
BioCholawat Pacharinsak, DVM, PhD Associate Professor and Director of Anesthesia, Pain Management, and Surgery, at Stanford University’s Department of Comparative Medicine; he is a Diplomate of the American College of Veterinary Anesthesia and Analgesia (DACVAA). He received his DVM from Chulalongkorn University, Thailand and trained in an Anesthesiology/Pain Management residency program and received his Master's degree at Washington State University. He completed his PhD in Comparative and Molecular Biosciences from the University of Minnesota. Prior to arriving at Stanford, Dr. Pacharinsak was a faculty member in Anesthesiology and Pain Management at Michigan State University and Purdue University; and served as a Clinical Specialist at UCLA’s David Geffen School of Medicine. His research focuses on understanding the neurobiology of cancer pain, chemotherapeutic-induced peripheral neuropathy, acute surgical pain models, and methods to improve clinical pain management e.g. sustained release analgesics supporting refinement. Research methodology includes electrophysiologic and behavioral techniques.
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Julia Palacios
Associate Professor of Statistics, of Biomedical Data Science and, by courtesy, of Biology
BioDr. Palacios seek to provide statistically rigorous answers to concrete, data driven questions in evolutionary genetics and public health . My research involves probabilistic modeling of evolutionary forces and the development of computationally tractable methods that are applicable to big data problems. Past and current research relies heavily on the theory of stochastic processes, Bayesian nonparametrics and recent developments in machine learning and statistical theory for big data.
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Daniel Palanker, PhD
Professor of Ophthalmology and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsInteractions of electric field and light with biological cells and tissues and their applications to imaging, diagnostics, therapeutics and prosthetics, primarily in ophthalmology.
Specific fields of interest:
Electronic retinal prosthesis;
Electronic enhancement of tear secretion;
Electronic control of blood vessels;
Non-damaging retinal laser therapy;
Ultrafast laser surgery;
Interferometric imaging of neural signals;
Cell transplantation and retinal plasticity. -
Megan J. Palmer
Adjunct Professor, Bioengineering
BioDr. Megan J. Palmer is the Executive Director of Bio Policy & Leadership Initiatives at Stanford University. In this role, Dr. Palmer leads integrated research, teaching and engagement programs to explore how biological science and engineering is shaping our societies, and to guide innovation to serve public interests. Based in the Department of Bioengineering, where she is also an Adjunct Professor, she works closely both with groups across the university and with stakeholders in academia, government, industry and civil society around the world.
In addition to fostering broader efforts, Dr. Palmer leads a focus area in biosecurity in partnership with the Freeman Spogli Institute for International Studies (FSI) at Stanford. Projects in this area examine how security is conceived and managed as biotechnology becomes increasingly accessible. Her current projects include assessing strategies for governing dual use research, analyzing the diffusion of safety and security norms and practices, and understanding the security implications of alternative technology design decisions.
Dr. Palmer has created and led many programs aimed at developing and promoting best practices and policies for the responsible development of bioengineering. She currently co-chairs the World Economic Forum Global Future Council on Synthetic Biology and in a member of the Council of the Engineering Biology Research Consortium (EBRC). For the last ten years she has led programs in safety, security and social responsibility for the international Genetically Engineered Machine (iGEM) competition, which in 2019 involved over 6000 students in 353 teams from 48 countries. She also founded and serves as Executive Director of the Synthetic Biology Leadership Excellence Accelerator Program (LEAP), an international fellowship program in biotechnology leadership. She advises and works with many other organizations on their strategies for the responsible development of bioengineering, including serving on the board of directors of Revive & Restore, a nonprofit organization advancing biotechnologies for conservation.
Previously, Megan was a Senior Research Scholar and William J. Perry Fellow in International Security at the Center for International Security and Cooperation (CISAC), part of FSI, where she is now an affiliated researcher. She also spent five years as Deputy Director of Policy and Practices for the multi-university NSF Synthetic Biology Engineering Research Center (Synberc). She has previously held positions as a project scientist at the California Center for Quantitative Bioscience at the University of California Berkeley (where she was an affiliate of Lawrence Berkeley National Labs), and a postdoctoral scholar in the Bioengineering Department at Stanford University. Dr. Palmer received her Ph.D. in Biological Engineering from M.I.T. and a B.Sc.E. in Engineering Chemistry from Queen’s University, Canada. -
Theo Palmer
Professor of Neurosurgery, Emeritus
Current Research and Scholarly InterestsMembers of the Palmer Lab study the biology of neural stem cells in brain development and in the adult. Our primary goal is to understand how genes and environment synergize in influencing stem cell behavior during development and how mild genetic or environmental risk factors for disease may synergize in their detrimental effects on brain development or in the risk of neuronal loss in age-related degenerative disease.
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Stephen Palumbi
Jane and Marshall Steel Jr. Professor of Marine Sciences, Professor of Oceans and of Biology
Current Research and Scholarly InterestsWe're interested in ecological, evolutionary, and conservation questions related to marine (and sometimes terrestrial) organisms and ecosystems. We use evolutionary genetics and molecular ecology techniques, and our fieldwork takes us all around the world. Currently, we're studying coral diversity, the adaptive potential of corals in response to climate change, the movement of organisms between marine reserves, genetic changes in abalone in response to environmental.
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Jennifer Pan
Sir Robert Ho Tung Professor of Chinese Studies, Professor of Communication, Senior Fellow at the Freeman Spogli Institute for International Studies and Professor, by courtesy, of Political Science and of Sociology
BioJennifer Pan is a political scientist whose research focuses on political communication, digital media, and authoritarian politics. She is the Sir Robert Ho Tung Professor of Chinese Studies, Professor of Communication and (by courtesy) Political Science, and a Senior Fellow at the Freeman Spogli Institute.
Dr. Pan's research uses experimental and computational methods with large-scale datasets on political activity to answer questions about the role of digital media in authoritarian and democratic politics, including how political censorship, propaganda, and information manipulation work in the digital age and how preferences and behaviors are shaped as a result. Her book, Welfare for Autocrats: How Social Assistance in China Cares for its Rulers (Oxford, 2020) shows how China's pursuit of political order transformed the country’s main social assistance program, Dibao. Her papers have appeared in peer reviewed publications such as the American Political Science Review, American Journal of Political Science, Journal of Politics, Political Communication, and Science.
She graduated from Princeton University, summa cum laude, and received her Ph.D. from Harvard University’s Department of Government. -
Alan C. Pao
Associate Professor of Medicine (Nephrology) and, by courtesy, of Urology
Current Research and Scholarly InterestsWe are broadly interested in how the kidneys control salt, water, and electrolyte homeostasis in the body. Our disease focus is on kidney stone disease. We use cultured kidney cells, transgenic mice, human plasma/urine samples, and electronic health record data to study the pathogenesis of kidney stone disease. Our therapeutic focus is on the development of small molecule compounds that can be used for kidney stone prevention.
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Peter Parham
Professor of Structural Biology and, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsThe Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.
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Victoria Parikh
Assistant Professor of Medicine (Cardiovascular Medicine)
BioDr. Parikh is a clinician scientist who cares for patients with and studies inherited (genetic) cardiovascular disease. She is the director of the Stanford Center for Inherited Cardiovascular Disease (SCICD) which is one of the largest of its kind in the country. SCICD integrates clinical and basic science with the expert care of patients with genetic cardiovascular conditions (e.g., cardiomyopathies, arrhythmias and vascular diseases). It provides cutting edge care for thousands of patients and families across the lifespan and integrates medical, surgical and genetics care. Our team includes physicians, nurses, advanced practice providers, genetic counselors, exercise physiologists and scientists.
Dr. Parikh's own clinical practice and laboratory are focused on the genetics of cardiomyopathies and their associated arrhythmogenic substrates. She completed clinical cardiology fellowship at Stanford School of Medicine and her medical residency at the University of California, San Francisco. Funded by multiple research grants from the NIH, her lab seeks to identify novel mechanisms and therapeutic technologies for genetic cardiomyopathy as well as better understand the natural histories of patients affected by these diseases. -
David Jaehyun Park
Clinical Instructor, Neurosurgery
BioDavid Park, MD, PhD, is a neurosurgeon who graduated from medical school at the Catholic University of Korea in Seoul, South Korea. He then completed his internship and residency training in the Department of Neurosurgery at Seoul St. Mary’s Hospital. He became a board-certified neurosurgeon in South Korea in 2014 and subsequently completed a 2-year fellowship at the same hospital, specializing in brain tumor surgery and skull base surgery. During his residency, he also attended graduate school while practicing neurosurgery as a trainee and successfully defended his Ph.D. thesis, titled “Combination therapy for gliomas using temozolomide and interferon-beta secreting human bone marrow-derived mesenchymal stem cells,” in 2015.
After completing his fellowship in South Korea, Dr. Park moved to Singapore in 2016 and worked as a Clinical Fellow (Clinical Associate) at the National Neuroscience Institute for one year, focusing on Neurosurgical Oncology and Skull Base Surgery.
In 2017, Dr. Park joined Dr. Christian Badr’s lab at Massachusetts General Hospital, Harvard Medical School, as a Postdoctoral Research Fellow, conducting translational research on glioblastoma and studying the role of fatty acids and lipid metabolism in glioblastoma to complement his clinical expertise.
During this time, Dr. Park also launched a startup based on his invention of an intraoperative diagnostic tool for tumor detection during glioma surgery. He collaborated with bioengineers at M.I.T. to develop a prototype and secured seed funding from the MIT Sandbox Innovation Fund Program. As an alumnus of the MIT Sandbox program, he continues to develop this project.
In 2020, Dr. Park served as a Neurosurgical Oncology and Radiosurgery Fellow (Teaching Associate) for a year at North Shore University Hospital, Zucker School of Medicine at Hofstra/Northwell, in Long Island, New York, where he worked with Dr. Michael Schulder on brain tumor surgery including advanced techniques, such as Laser Interstitial Thermal Therapy (LITT) and Stereotactic Radiosurgery (SRS).
From July 2021 to June 2022, he completed another fellowship in Neurosurgical Oncology and Radiosurgery at the Cleveland Clinic in Cleveland. He devoted his efforts to minimally invasive neurosurgical techniques such as LITT and Gamma Knife SRS, as well as awake brain tumor surgery under the guidance of Drs. Gene Barnett, Lilyana Angelov, and Ali Mohammadi.
As of July 2022, Dr. Park has joined the Department of Neurosurgery at Stanford University as a Clinical Instructor, working with Dr. Steven D. Chang in the fields of Neurosurgical Oncology and CyberKnife SRS. -
Jon Park, MD, FRCSC
Saunders Family Professor
Current Research and Scholarly InterestsNon-fusion dynamic spinal stabilization, artificial disc technologies, and regenerative spinal technologies.
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Karen J. Parker, PhD
Truong-Tan Broadcom Endowed Professor and Professor, by courtesy, of Comparative Medicine
Current Research and Scholarly InterestsThe Parker Lab conducts research on the biology of social functioning in monkeys, typically developing humans, and patients with social impairments.
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Vanessa Parli
Director of Research Programs, Institute for Human-Centered Artificial Intelligence (HAI)
BioVanessa Parli is the Director of Research at HAI. She leads the HAI grant programs, research convenings, student groups and “state of AI” reports such as the AI 100 and the AI Index where she is a member of the Steering Committee. Her team also analyzes the effectiveness of these programs to continuously improve HAI’s ability to foster interdisciplinary research collaborations internal and external to Stanford. Prior to Stanford, Vanessa worked in management consulting where she utilized statistics, machine learning and other data science methodologies to advise government agencies, large biotech companies and nonprofit organizations. Vanessa holds an MS in Engineering Management and Computational Mathematics from Johns Hopkins University and a BA in Industrial Engineering from Arizona State University.
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Josef Parvizi, MD, PhD
Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery
BioDr. Parvizi completed his medical internship at Mayo Clinic, neurology training at Harvard, and subspecialty training in clinical neurophysiology and epilepsy at UCLA before joining the Department of Neurology and Neurological Sciences at Stanford in 2007. Dr. Parvizi directs the Stanford Program for Medication Resistant Epilepsies and specializes in surgical treatments of intractable focal epilepsies. Dr. Parvizi is the principal investigator in the Laboratory of Behavioral and Cognitive Neuroscience, where he leads a team of investigators to study the human brain. http://med.stanford.edu/parvizi-lab.html.
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Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsThe research focus of the lab is to understand molecular mechanisms underlying neurodevelopmental disorders associated with premature birth, neonatal and fetal brain injury with the long-term goal of translating the lab’s findings into therapeutics. The research team employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology, animal models and neural cells differentiated from patient-derived induced pluripotent stem (iPS) cells. In particular, the lab is using a powerful 3D human brain-region specific organoid system developed at Stanford (Nature Methods, 2015; Nature Protocols, 2018) to ask questions about brain injury during development.
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Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Chirag Patel, MD, PhD
Member, Cardiovascular Institute
Current Research and Scholarly InterestsNeuro-oncology, Clinical Trials, Tumor Treating Fields (TTFields), Molecular/PET Imaging, Neuroimaging, Immunotherapy, Big Data Analysis
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Zara Patel, MD
Professor of Otolaryngology - Head & Neck Surgery (OHNS)
BioDr. Zara M. Patel is Director of Endoscopic Skull Base Surgery and a Professor of Otolaryngology and, by courtesy, of Neurosurgery at Stanford. She was born and raised in St. Louis, completed her MD at the Oregon Health and Sciences University in Portland, Oregon and completed her residency training in otolaryngology at Mount Sinai Medical Center in New York, NY. After pursuing fellowship training in rhinology and endoscopic skull base surgery at Stanford University, she was recruited to join the Emory University faculty in Atlanta in 2011. After four years, the rhinology division recruited her back to the West coast to rejoin the department here at Stanford University in 2015.
Dr. Patel is an expert in advanced endoscopic sinus and skull base surgery. She treats patients with a wide variety of rhinologic complaints, including chronic sinus infection or inflammation, sinus disease that has failed medical therapy, sinus disease that has failed prior surgical therapy, cerebrospinal fluid leaks, benign and and malignant sinus and skull base tumors, as well as olfactory disorders.
She has served as Chair of the Education Committee and Member of the Board of Directors for the American Rhinologic Society, is current Chair of the Rhinology and Allergy Education Committee for the American Academy of Otolaryngology - Head and Neck Surgery, and has developed a multitude of educational materials for both physicians and patients to help them better understand rhinologic disorders. She is passionate about educating patients to allow them to make the best decisions about their own care, leading to better outcomes.
Dr. Patel has published widely in topics such as avoiding complications in endoscopic sinus surgery, chronic rhinosinusitis in the immunosuppressed patient population, new devices and techniques for endoscopic skull base surgery, and olfactory dysfunction. She continues to perform research in these areas, and is currently collaborating with neuroscientists and engineers to develop technology that she hopes will eventually help cure patients with smell loss, and potentially even help those with neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. -
John M. Pauly
Reid Weaver Dennis Professor
BioInterests include medical imaging generally, and magnetic resonance imaging (MRI) in particular. Current efforts are focused on medical applications of MRI where real-time interactive imaging is important. Two examples are cardiac imaging, and the interactive guidance of interventional procedures. Specific interests include rapid methods for the excitation and acquisition of the MR signal, and the reconstruction of images from the data acquired using these approaches.
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Kim Butts Pauly
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering and of Bioengineering
Current Research and Scholarly InterestsWe are investigating and developing, and applying focused ultrasound in neuromodulation, blood brain barrier opening, and ablation for both neuro and body applications.
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Marco Pavone
Associate Professor of Aeronautics and Astronautics and, by courtesy, of Electrical Engineering and of Computer Science
BioDr. Marco Pavone is an Associate Professor of Aeronautics and Astronautics at Stanford University, where he directs the Autonomous Systems Laboratory and the Center for Automotive Research at Stanford. He is also a Distinguished Research Scientist at NVIDIA where he leads autonomous vehicle research. Before joining Stanford, he was a Research Technologist within the Robotics Section at the NASA Jet Propulsion Laboratory. He received a Ph.D. degree in Aeronautics and Astronautics from the Massachusetts Institute of Technology in 2010. His main research interests are in the development of methodologies for the analysis, design, and control of autonomous systems, with an emphasis on self-driving cars, autonomous aerospace vehicles, and future mobility systems. He is a recipient of a number of awards, including a Presidential Early Career Award for Scientists and Engineers from President Barack Obama, an Office of Naval Research Young Investigator Award, a National Science Foundation Early Career (CAREER) Award, a NASA Early Career Faculty Award, and an Early-Career Spotlight Award from the Robotics Science and Systems Foundation. He was identified by the American Society for Engineering Education (ASEE) as one of America's 20 most highly promising investigators under the age of 40. His work has been recognized with best paper nominations or awards at a number of venues, including the European Conference on Computer Vision, the IEEE International Conference on Robotics and Automation, the European Control Conference, the IEEE International Conference on Intelligent Transportation Systems, the Field and Service Robotics Conference, the Robotics: Science and Systems Conference, and the INFORMS Annual Meeting.
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Jonathan Payne
Dorrell William Kirby Professor, Senior Associate Dean for Faculty Affairs, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Biology,
Current Research and Scholarly InterestsMy goal in research is to understand the interaction between environmental change and biological evolution using fossils and the sedimentary rock record. How does environmental change influence evolutionary and ecological processes? And conversely, how do evolutionary and ecological changes affect the physical environment? I work primarily on the marine fossil record over the past 550 million years.
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Roy Pea
Director, H-STAR, David Jacks Professor of Education and Professor, by courtesy, of Computer Science
Current Research and Scholarly Interestslearning sciences focus on advancing theories, research, tools and social practices of technology-enhanced learning of complex domains
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Kabir Peay
Director of the Earth Systems Program, Associate Professor of Biology, of Earth System Science and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsOur lab studies the ecological processes that structure natural communities and the links between community structure and the cycling of nutrients and energy through ecosystems. We focus primarily on fungi, as these organisms are incredibly diverse and are the primary agents of carbon and nutrient cycling in terrestrial ecosystems. By working across multiple scales we hope to build a 'roots-to-biomes' understanding of plant-microbe symbiosis.
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Donna Peehl, PhD
Professor (Research) of Urology, Emerita
Current Research and Scholarly InterestsMy research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases.
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Kaci Danae Peel
Events Manager, Institute for Human-Centered Artificial Intelligence (HAI)
Current Role at StanfordEvent Planner, Stanford Institute for Human-Centered AI (HAI)
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Mark Pegram
Susy Yuan-Huey Hung Professor
Current Research and Scholarly InterestsMolecular mechanisms of targeted therapy resistance in breast and other cancers
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Norbert Pelc
Boston Scientific Applied Biomedical Engineering Professor and Professor of Radiology, Emeritus
Current Research and Scholarly InterestsBroadly, Dr. Pelc is interested in the physics, engineering and mathematics of medical imaging, especially computed tomography, digital x-ray imaging, magnetic resonance imaging, and hybrid multimodality systems. His current research is concentrated in the development of computed tomography systems with higher image quality and dose efficiency, in the characterization of system performance, and in the development and validation of new clinical applications.
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Gary Peltz
Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsThe laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue.
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Jon-Paul Pepper, MD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly InterestsFacial paralysis is a debilitating condition that affects thousands of people. Despite excellent surgical technique, we are currently limited by the regenerative capacity of the body. The mission of our research is to identify new treatments that improve current facial paralysis treatments. We do this by exploring the regenerative cues that the body uses to restore tissue after nerve injury, in particular through pathways of neurogenesis and nerve repair in small mammals.
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Marco Perez
Associate Professor of Medicine (Cardiovascular Medicine)
BioDr. Marco Perez's research goal is to better understand the fundamental causes of cardiovascular disease through the study of genetics and epidemiology. His group studies the genetic variations and environmental exposures that are associated with conditions such as atrial fibrillation and heart failure. He has led the studies of atrial fibrillation in Women's Health Initiative, one of the largest nation-wide population-based cohorts. He is currently conducting a large study monitoring for silent or asymptomatic atrial fibrillation in women from the WHI randomized to exercise intervention, and was co-PI of the Apple Heart Study, a clinical trial that validated the ability of a smartwatch to detect atrial fibrillation. He is now PI of the Clinical Coordinating Center at Stanford for the REACT-AF which is a clinical trial to evaluate efficacy and safety of a "pill-in-the pocket" approach to anticoagulation for AF using a smartwatch. He is interested in understanding the paradox that atrial fibrillation is less common in African Americans and Hispanics, despite a greater burden of risk factors such as hypertension. As director of the Stanford Inherited Arrhythmia Clinic, he evaluates families with rare inherited arrhythmias associated with sudden death such as Long QT and Brugada Syndromes and explores their links with novel genes. He also studies the genetic causes of very early onset atrial fibrillation. He also studies how best to use the electrocardiogram and imaging modalities using Machine Learning techniques to identify patients at risk for cardiovascular disease. Dr. Perez receives funding from the NIH/NHLBI, Apple Inc., Janssen and the Colson Foundation.
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VJ Periyakoil, Professor of Medicine
Professor of Medicine (Primary Care and Population Health)
Current Research and Scholarly InterestsMy research focuses on the intersection of biological, psychosocial and cultural aspects of care of persons with chronic and serious illnesses including dementia.
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Claudia Katharina Petritsch
Associate Professor (Research) of Neurosurgery
Current Research and Scholarly InterestsThe Petritsch lab broadly investigates underlying causes for the intra-tumoral heterogeneity and immune suppression in brain tumors from a neuro-developmental perspective. Defective cell fate decisions fuel the intra-humoral heterogeneity and plasticity in human brain tumors and may contribute to immune suppression. We use patient-derived models as avatars to study how brain cells control the fate of their progeny, whereby we unravel novel points of vulnerabilities in brain tumor cells.
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Dmitri Petrov
Michelle and Kevin Douglas Professor in the School of Humanities and Sciences
Current Research and Scholarly InterestsEvolution of genomes and population genomics of adaptation and variation
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Suzanne Pfeffer
Emma Pfeiffer Merner Professor of Medical Sciences
Current Research and Scholarly InterestsThe major focus of our research is to understand the molecular basis of inherited Parkinson's Disease (PD). We focus on the LRRK2 kinase that is inappropriately activated in PD and how it phosphorylates Rab GTPases, blocking the formation of primary cilia in specific regions of the brain. The absence of primary cilia renders cells unable to carry out Hedgehog signaling that is critical for neuroprotective pathways that sustain dopamine neurons.
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Adolf Pfefferbaum
Professor of Psychiatry and Behavioral Sciences, Emeritus
Current Research and Scholarly InterestsDevelopment and application of magnetic resonance imaging approaches for in vivo studies of human and animal brain integrity in neurodegenerative conditions, including alcoholism, HIV infection, Alzheimer's disease, and normal aging
