Stanford University
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Kacper Rogala
Assistant Professor of Structural Biology and of Chemical and Systems Biology
Current Research and Scholarly InterestsOur team is fascinated by how cells make growth decisions — to grow or not to grow. In order to grow, cells require nutrients, and we are unraveling how cells use specialized protein sensors and transporters to sense and traffic nutrients in between various compartments. We use approaches from structural biology, chemical biology, biophysics, biochemistry, and cell biology — to reveal the mechanisms of basic biological processes, and we develop chemical probes that modulate them.
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Kevin Rose
Postdoctoral Scholar, Structural Biology
Current Research and Scholarly InterestsI am interested in studying organelle dysfunction and host cell responses at the highest resolution possible in natively preserved tissues. To do this, I couple correlative light and cryo-Electron Tomography (cryo-ET) and perform ultrastructural analysis of healthy and diseased organelles. This technique hopes to uncover new molecular details of pathophysiology so that we can improve our understanding of diseases such as cancer and neurodegeneration to improve the rationale therapeutic design.