Stanford University
Showing 61-80 of 121 Results
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Amy Nava
Postdoctoral Scholar, Molecular and Cellular Physiology
BioMy long-term scientific ambition entails establishing an interdisciplinary and diverse laboratory primarily focused on countering antibiotic resistance. This objective comprises three central elements: elucidating the bacterial calcium transduction pathway, crafting innovative therapeutics to treat antibiotic-resistant deep tissue infections, and comprehending how calcium signaling stimulates bacterial pathogenesis mechanisms.
The foundation of my research experience supports the existence of calcium signal transduction pathways in bacteria. This conclusion aligns with various studies that drew indirect connections between calcium signaling and the regulation of other bacterial physiological processes, including virulence.
A thorough grasp of the mechanism by which calcium regulates multidrug-resistant functions, such as efflux, is a crucial stride toward mitigating the global crisis of antibiotic resistance. I am dedicated to contributing significantly to this path of exploration, ultimately driving impactful scientific development and healthcare improvement. -
Lucy Erin O'Brien
Associate Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMany adult organs tune their functional capacity to variable levels of physiologic demand. Adaptive organ resizing breaks the allometry of the body plan that was established during development, suggesting that it occurs through different mechanisms. Emerging evidence points to stem cells as key players in these mechanisms. We use the Drosophila midgut, a stem-cell based organ analogous to the vertebrate small intestine, as a simple model to uncover the rules that govern adaptive remodeling.
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Tino Pleiner
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsThe Pleiner lab combines mechanistic cell biology, structural biochemistry and protein engineering to dissect the pathways and molecular machines that mature human membrane proteins to a fully functional state. We also develop alpaca-derived and synthetic nanobodies as tools to modulate intracellular pathways that globally regulate protein homeostasis in health and disease.