Stanford University
Showing 191-200 of 282 Results
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David Prince
Edward F. and Irene Thiele Pimley Professor of Neurology and the Neurological Sciences, Emeritus
Current Research and Scholarly InterestsExperiments examine
1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability
2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors;
3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.
4. prophylaxis of postraumatic epilepsy
5. Neocortical interneuronal function/modulation -
Lindsey Rasmussen
Clinical Associate Professor, Pediatrics - Critical Care
Clinical Associate Professor (By courtesy), Neurology & Neurological SciencesCurrent Research and Scholarly InterestsMy research interests reside in the field of Neurocritical Care Medicine. My research focus has included inflammation following traumatic brain injury, outcome prediction after cardiac arrest, and neuro-monitoring in the pediatric intensive care setting. These interests are integrated clinically to focus on the merging of specialized neurologic monitoring and care with prognostic efforts in critically ill patients.
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Babak Razavi, MD, PhD
Clinical Associate Professor, Neurology & Neurological Sciences
BioDr. Razavi's clinical interests are in medically refractory epilepsies and using high density EEG (electroencephalogram) for better localization of seizure foci. His research areas include using advanced digital signal processing and engineering techniques for analyzing EEG and using seizures as a model for understanding consciousness.
Dr. Razavi is the Founder and Director of DEL - Distributed EEG Lab. DEL's vision is to make EEG easy as 1, 2, 3. We turn complexity into simplicity. We are distributed in time and space. DEL was founded in the spirit of cloud computing, networking, and the notion that research in collaboration is more exciting and fruitful than in isolation. Everyone contributes - no matter how small; everyone wins - no matter how big. It was inspired by the mentorship of Dr. Kimford Meador and Dr. Robert Fisher. All you need is access to a computer and the internet.
DEL is the ideal collaborative environment for students (undergraduate and graduate) and faculty who would like to: (1) apply ready-to-use advanced analytical techniques to test specific hypotheses in cognition, neuroscience and epilepsy, and (2) develop and test new algorithms for analyzing EEG and other biological signals. -
Lawrence Recht, MD
Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsOur laboratory focuses on two interrelated projects: (1) assessment of glioma development within the framework of the multistage model of carcinogenesis through utilization of the rodent model of ENU neurocarcinogenesis; and (2) assessment of stem cell specification and pluripotency using an embryonic stem cell model system in which neural differentiation is induced.
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Richard J. Reimer, MD
Associate Professor of Neurology (Adult Neurology)
Current Research and Scholarly InterestsReimer Lab interests
A primary interest of our lab is to understand how nerve cells make and recycle neurotransmitters, the small molecules that they use to communicate with each other. In better defining these processes we hope to achieve our long-term goal of identifying novel sites for treatment of diseases such as epilepsy and Parkinson Disease. In our studies on neurotransmitter metabolism we have focused our efforts on transporters, a functional class of proteins that move neurotransmitters and other small molecules across membranes in cells. Transporters have many characteristics that make them excellent pharmacological targets, and not surprisingly some of the most effective treatments for neuropsychiatric disorders are directed at transporters. We are specifically focusing on two groups of transporters vesicular neurotransmitter transporters that package neurotransmitters into vesicles for release, and glutamine transporters that shuttle glutamine, a precursor for two major neurotransmitters glutamate and GABA, to neurons from glia, the supporting cells that surround them. We are pursuing these goals through molecular and biochemical studies, and, in collaboration with the Huguenard and Prince labs, through physiological and biosensor based imaging studies to better understand how pharmacological targeting of these molecules will influence neurological disorders.
A second interest of our lab is to define mechanism underlying the pathology of lysosomal storage disorders. Lysosomes are membrane bound acidic intracellular organelles filled with hydrolytic enzymes that normally function as recycling centers within cells by breaking down damaged cellular macromolecules. Several degenerative diseases designated as lysosomal storage disorders (LSDs) are associated with the accumulation of material within lysosomes. Tay-Sachs disease, Neimann-Pick disease and Gaucher disease are some of the more common LSDs. For reasons that remain incompletely understood, these diseases often affect the nervous system out of proportion to other organs. As a model for LSDs we are studying the lysosomal free sialic acid storage disorders. These diseases are the result of a defect in transport of sialic acid across lysosomal membranes and are associated with mutations in the gene encoding the sialic acid transporter sialin. We are using molecular, genetic and biochemical approaches to better define the normal function of sialin and to determine how loss of sialin function leads to neurodevelopmental defects and neurodegeneration associated with the lysosomal free sialic acid storage disorders. -
Eric Rider, MD
Clinical Assistant Professor, Neurology & Neurological Sciences
BioDr. Rider is a board-certified, fellowship-trained neuromuscular neurologist with the Neuromuscular Program at the Stanford Neuroscience Health Center. He is also a clinical assistant professor in the Department of Neurology & Neurological Sciences at Stanford University School of Medicine.
Dr. Rider specializes in treating neuromuscular disease, including motor neuron disease, disorders of the neuromuscular junction, peripheral and focal neuropathies, as well as other acquired or genetic conditions that cause muscular deterioration, muscle weakness, and nerve damage. He practices both Comprehensive Neurology and Neuromuscular Medicine in Palo Alto and Emeryville.
Dr. Rider earned his medical degree at the University of California, San Francisco and completed residency at Stanford. He also completed fellowship training in Neuromuscular Medicine at UCSF. He has a passion for teaching neurology to students and patients. He was awarded the Fishers and Dunn teaching award for medical student teaching as a resident.
Dr. Rider is a member of the American Academy of Neurology and American Association of Neuromuscular & Electrodiagnostic Medicine.
