Stanford University
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Siddharth Krishnan
Assistant Professor of Electrical Engineering, and by courtesy, of Bioengineering and of Materials Science and Engineering
Current Research and Scholarly InterestsThe Krishnan Lab develops bioelectronic devices, tools and systems for closed loop disease management. Our work is divided into the following broad areas:
1. Biohybrid electronics for therapy and sensing: we combine living cells as functional parts of implantable devices, leveraging their ability to produce complex biologic therapeutics in a constitutive or triggerable manner, and their ability to sense their complex dynamic environment. These efforts are focused on developed functional cures for diseases like Type I Diabetes and other conditions requiring the regular infusion of proteins, peptides or antibody drugs.
2. Digital drug release systems for particulate forms of biologic drugs: Many complex protein and peptide drugs are not stable in solution, thereby frustrating the ability to delivery them through pumps and autoinjectors. This need is particularly acute for drugs that need to be administered as emergency rescue therapies, such as glucagon in the context of type 1 Diabetes. We develop implantable, miniaturized microelectromechanical devices that can store particulate (powders, pills) forms of these drugs and release them in a close loop manner based on wireless inputs from sensors.
3. Wearable sensors: Wearables to detect biophysical (temperature, flow, cardiac activity) and biochemical markers of health are gaining importance for closed-loop disease management and personalized medicine. We design hardware for on-chip molecular profiling based on sampling biofluids in noninvasive or minimally invasive formats.
4. New wireless power architectures for implantable bioelectronics: We develop high-power, high-efficiency strongly coupled power harvesting system to power battery-free implant systems. -
Yuva Karthik Krishnapillai B.S.
Affiliate, Multispecialty Anesthesiology
BioYuva Krishnapillai is a current research scholar affiliated with the Department of Anesthesiology, Perioperative and Pain Medicine at Stanford University. His focus of study revolves around perioperative neuroscience, EEG-defined brain states, and immediate and long-term cognitive change with the goal of improving cognitive and functional outcomes after surgery. Krishnapillai is involved in numerous prospective and retrospective research investigations examining perioperative outcomes and is involved in collaborative work with UC Riverside School of Medicine and UC San Francisco School of Medicine.
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Christina Krist
Associate Professor of Education
BioDr. Krist's research examines how science learning environments can be structured to support students' epistemic agency, sense of belonging, and authority as knowers, with particular attention to students and communities who are systematically marginalized in STEM. This work spans three levels of design: classroom practice, course structure, and community partnership. Her projects include developing professional development models that support K-12 teachers in building community partnerships for justice-centered science teaching, supporting the structural redesign of introductory undergraduate STEM courses to strengthen students' epistemologies and sense of belonging, and collaborative work with families and local communities to drive educational transformation. Several current projects extend this agenda to new domains, including the use of generative AI to support teacher planning and the development of strengths-based approaches to understanding student engagement.
Dr. Krist received her PhD in Learning Sciences from Northwestern University in 2016 and was a postdoctoral scholar at the University of Maryland from 2016-2017. Her early career work has been supported by an NAEd/Spencer Postdoctoral Fellowship as well as grants from the National Science Foundation and the National Institutes of Health. She was recently recognized with NARST’s 2023 Early Career Research Award. -
David Krist, MD, PhD
Affiliate, Department Funds
Resident in SurgeryBioMD, Carle Illinois College of Medicine (2024)
PhD, Chemistry, Northwestern University (2016)
