Vice Provost and Dean of Research
Showing 1,811-1,820 of 2,483 Results
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Elisabetta Viani Puglisi
Associate Professor (Research) of Structural Biology
Current Research and Scholarly InterestsViral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with biochemical and biophysical methods to understand functional properties. The goal of this research is to gain a molecular view of HIV replication initiation, and use this information to develop new therapeutic approaches to combat HIV.
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Joseph (Jody) Puglisi
Jauch Professor and Professor of Structural Biology
Current Research and Scholarly InterestsThe Puglisi group investigates the role of RNA in cellular processes and disease. We investigate dynamics using single-molecule approaches. Our goal is a unified picture of structure, dynamics and function. We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections. A long-term goal is to target processes involving RNA with novel therapeutic strategies.
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Patrick Lee Purdon
Professor of Anesthesiology, Perioperative and Pain Medicine (Department Research) and, by courtesy, of Bioengineering
BioMy research integrates neuroimaging, biomedical signal processing, and the systems neuroscience of general anesthesia and sedation.
My group conducts human studies of anesthesia-induced unconsciousness, using a variety of techniques including multimodal neuroimaging, high-density EEG, and invasive neurophysiological recordings used to diagnose medically refractory epilepsy. We also develop novel methods in neuroimaging and biomedical signal processing to support these studies, as well as methods for monitoring level of consciousness under general anesthesia using EEG. -
Stanley Qi
Associate Professor of Bioengineering
BioStanley Qi (publishing as Lei S. Qi) is a pioneer in the field of genome engineering and the architect of the foundational technologies that transitioned CRISPR from a "cutting" tool into a universal platform for Programmable Biology. As the inventor of CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa), Qi established the first methods for the precise, reversible, and targeted regulation of the human genome without altering the DNA sequence.
The Qi Lab integrates scalable genomic perturbation with live-cell and super-resolution imaging and computation-guided design to redefine the boundaries of cellular control. Under Dr. Qi’s leadership, the group has fundamentally expanded the genome engineering toolbox, evolving CRISPR from a single editing tool into a multidimensional platform for the precise control of dynamic and spatial cell states. This work includes establishing foundational technologies and architectures for precise epigenetic editing, multiplexed regulation of the transcriptome, programmable 3D genome organization, and spatial control of RNA logistics. By pioneering real-time visualization of chromatin dynamics and RNA in living cells, the lab provides an unprecedented window into the fundamental "control principles of life."
This principle-driven technology lineage has moved into the clinic, with the lab's compact epigenetic editor currently in first-in-human clinical testing for FSHD muscular dystrophy (NCT06907875). This milestone represents a core mission of the lab: translating foundational engineering into next-generation therapeutics that act predictably as dynamic, complex systems.
Beyond single-cell control, the Qi Lab is building a framework for synthetic cell–cell communication, with a particular emphasis on the bidirectional interplay between immune cells and neurons. The lab’s goal is to move beyond describing molecular parts to discovering fundamental control principles in living systems: how regulatory landscapes create stable states and memory, how spatial genome–RNA organization shapes dynamic responses, and how engineered cell–cell interactions can generate emergent multicellular behaviors.
By integrating computational design with experimental biology, Dr. Qi aims to identify the generalizable rules linking molecular programs to systems-level physiology. He is a Chan Zuckerberg Biohub Investigator and an Institute Scholar at the Sarafan ChEM-H, and is dedicated to shaping the technical and ethical frameworks that will define the future of human genome engineering. -
Xiang Qian
Stanford Medicine Endowed Director
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Clinical Professor (By courtesy), NeurosurgeryCurrent Research and Scholarly InterestsClinical Interests
-Pain Medicine:
Facial pain
Migraine and headache
Trigeminal Neuralgia and Glossopharyngeal neuralgia
Cancer Pain
Spine Disease
Neuropathic pain
Interventional Surgery
CT guided Procedure
Opioid Management
-Facial Nerve neuralgia and neuropathy
Hemifacial Spasm
CT guided awake RFA of facial nerve
Research Interests:
-Medical device development
-AI based headache diagnosis and management
-CT guided intervention
-Intra-nasal endoscopy guided procedure
-Optogenetics
-Mechanisms of neuropathic pain
-Ion channel and diseases
-Neurotoxicity of anesthetics -
Jian Qin
Associate Professor of Chemical Engineering
On Leave from 01/01/2026 To 06/30/2026BioJian Qin is an Associate Professor in the Department of Chemical Engineering at the Stanford University. His research focuses on development of microscopic understanding of structural and physical properties of soft matters by using a combination of analytical theory, scaling argument, numerical computation, and molecular simulation. He worked as a postdoctoral scholar with Juan de Pablo in the Institute for Molecular Engineering at the University of Chicago and with Scott Milner in the Department of Chemical Engineering at the Pennsylvania State University. He received his Ph.D. in the Department of Chemical Engineering and Materials Science at the University of Minnesota under the supervision of David Morse and Frank Bates. His research covers self-assembly of multi-component polymeric systems, molecular origin of entanglement and polymer melt rheology, coacervation of polyelectrolytes, Coulomb interactions in dielectrically heterogeneous electrolytes, and surface charge polarizations in particulate aggregates in the absence or presence of flow.
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Xiaojie Qiu
Assistant Professor of Genetics and, by courtesy, of Computer Science
Current Research and Scholarly InterestsAt the Qiu Lab, our mission is to unravel and predict the intricacies of gene regulatory networks and cell-cell interactions pivotal in mammalian cell fate transitions over time and space, with a special emphasis on heart evolution, development, and disease. We are a dynamic and interdisciplinary team, harnessing the latest advancements in machine learning as well as single-cell and spatial genomics by integrating the predictive power of systems biology with the scalability of machine learning,
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Stephen Quake
Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics
Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.
