Wu Tsai Neurosciences Institute
Showing 21-40 of 43 Results
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Atman Desai, MD
Clinical Professor, Neurosurgery
Current Research and Scholarly InterestsThe Stanford Spine Artificial Intelligence Laboratory develops data-driven technologies to improve diagnosis, surgical planning, and outcomes in spine care. Our research spans predictive modeling, computational imaging, spinal oncology, digital surgery, and real-world functional assessment using wearables. By integrating clinical, imaging, and functional data at scale, we aim to deliver clinically meaningful, patient-centered innovations for complex spinal disease.
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Manisha Desai (She/Her/Hers)
Kim and Ping Li Professor, Professor (Research) of Medicine (Quantitative Sciences Unit), of Biomedical Data Science and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Desai is the Director of the Quantitative Sciences Unit. She is interested in the application of biostatistical methods to all areas of medicine including oncology, nephrology, and endocrinology. She works on methods for the analysis of epidemiologic studies, clinical trials, and studies with missing observations.
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Jun Ding
Professor of Neurosurgery and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsNeural circuits of movement control in health and movement disorders
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Jennifer Dionne
Professor of Materials Science and Engineering, Senior Fellow at the Precourt Institute for Energy and Professor, by courtesy, of Radiology (Molecular Imaging Program at Stanford)
BioJennifer (Jen) Dionne is a Professor of Materials Science and Engineering and, by courtesy, of Radiology at Stanford. She is also a Chan Zuckerberg Biohub Investigator, deputy director of Q-NEXT (a DOE National Quantum Initiative), and co-founder of Pumpkinseed, a company developing quantum sensors to understand and optimize the immune system. From 2020-2023, Jen served as Stanford’s Inaugural Vice Provost of Shared Facilities, raising capital to modernize instrumentation, fund experiential education, foster staff development, and support new and existing users of the shared facilities. Jen received her B.S. degrees in Physics and Systems Science and Mathematics from Washington University in St. Louis, her Ph. D. in Applied Physics at the California Institute of Technology in 2009, and her postdoctoral training in Chemistry at Berkeley. As a pioneer of nanophotonics, she is passionate about developing methods to observe and control chemical and biological processes as they unfold with nanometer scale resolution, emphasizing critical challenges in global health and sustainability. Her research has developed culture-free methods to detect pathogens and their antibiotic susceptibility; amplification-free methods to detect and sequence nucleic acids and proteins; and new methods to image light-driven chemical reactions with atomic-scale resolution. Jen’s work has been featured in NPR, the Economist, Science, and Nature, and recognized with the NSF Alan T. Waterman Award, a NIH Director’s New Innovator Award, a Moore Inventor Fellowship, and the Presidential Early Career Award for Scientists and Engineers. She was also featured on Oprah’s list of “50 Things that will make you say ‘Wow’!”. She also perceives outreach as a critical component of her role and frequently collaborates with visual and performing artists to convey the beauty of science to the broader public.
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Scott Dixon
Professor of Biology
Current Research and Scholarly InterestsMy lab is interested in the relationship between cell death and metabolism. Using techniques drawn from many disciplines my laboratory is investigating how perturbation of intracellular metabolic networks can result in novel forms of cell death, such as ferroptosis. We are interested in applying this knowledge to find new ways to treat diseases characterized by insufficient (e.g. cancer) or excessive (e.g. neurodegeneration) cell death.
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Diana Do, MD
Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Do's research focuses on collaborative clinical trials to investigate novel treatments for retinal vascular diseases and ocular inflammation. She performs research to develop state of the art therapies for age-related macular degeneration, diabetic eye disease, retinal vein occlusion, retinal inflammation, and retinal detachment.
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Robert Dodd, MD, PhD
Associate Professor of Neurosurgery, of Radiology and, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly InterestsDr. Dodd is involved in clinical trials using endovascular coils that have a fiber coating that help heal aneurysms of the neck and can prevent an aneurysm from reforming. He uses minimally invasive endoscopic techniques to treat brain tumors.
Dodd's research interests are in cerebral blood vessel reactivity and stroke. -
Sebastian Doniach
Professor of Applied Physics and of Physics, Emeritus
Current Research and Scholarly InterestsStudy of changes in conformation of proteins and RNA using x-ray scattering
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Les Dorfman, MD
Professor of Neurology and Neurological Sciences, Emeritus
Current Research and Scholarly InterestsClinical electrophysiology of the peripheral and central nervous systems, including nerve conduction velocity; electromyography (EMG); and visual, auditory and somatosensory evoked potentials. Multiple sclerosis (MS) diagnosis and treatment. Neurological education.
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Anthony G. Doufas, M.D., Ph.D.
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD)
Current Research and Scholarly InterestsMy research focuses on the relationship between sleep abnormalities and pain behavior and opioid pharmacology in the postoperative, as well as chronic pain setting. More specifically, I am interested in delineating the effect of the different components of sleep-diosordered breathing, like nocturnal recurrent hypoxemia and sleep fragmentation on pain behavior in the acute and/or chronic care setting.
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Ron Dror
Cheriton Family Professor and Professor, by courtesy, of Structural Biology and of Molecular & Cellular Physiology
Current Research and Scholarly InterestsMy lab’s research focuses on computational biology, with an emphasis on 3D molecular structure. We combine two approaches: (1) Bottom-up: given the basic physics governing atomic interactions, use simulations to predict molecular behavior; (2) Top-down: given experimental data, use machine learning to predict molecular structures and properties. We collaborate closely with experimentalists and apply our methods to the discovery of safer, more effective drugs.
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David Drover
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD), Emeritus
Current Research and Scholarly InterestsField of clinical pharmacology. This involves analysis of what the body does to a drug (pharmacokinetics) and how exactly a specific drug affects the body (pharmacodynamics). His research starts at the level of new drug development with detailed analysis of the pharmacokinetics and pharmacodynamics of a medication.
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Shaul Druckmann
Associate Professor of Neurobiology, of Psychiatry and Behavioral Sciences and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsOur research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.
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Justin Du Bois
Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology
BioResearch and Scholarship
Research in the Du Bois laboratory spans reaction methods development, natural product synthesis, and chemical biology, and draws on expertise in molecular design, molecular recognition, and physical organic chemistry. An outstanding goal of our program has been to develop C–H bond functionalization processes as general methods for organic chemistry, and to demonstrate how such tools can impact the logic of chemical synthesis. A second area of interest focuses on the role of ion channels in electrical conduction and the specific involvement of channel subtypes in the sensation of pain. This work is enabled in part through the advent of small molecule modulators of channel function.
The Du Bois group has described new tactics for the selective conversion of saturated C–H to C–N and C–O bonds. These methods have general utility in synthesis, making possible the single-step incorporation of nitrogen and oxygen functional groups and thus simplifying the process of assembling complex molecules. To date, lab members have employed these versatile oxidation technologies to prepare natural products that include manzacidin A and C, agelastatin, tetrodotoxin, and saxitoxin. Detailed mechanistic studies of metal-catalyzed C–H functionalization reactions are performed in parallel with process development and chemical synthesis. These efforts ultimately give way to advances in catalyst design. A long-standing goal of this program is to identify robust catalyst systems that afford absolute control of reaction selectivity.
In a second program area, the Du Bois group is exploring voltage-gated ion channel structure and function using the tools of chemistry in combination with those of molecular biology, electrophysiology, microscopy and mass spectrometry. Much of this work has focused on studies of eukaryotic Na and Cl ion channels. The Du Bois lab is interested in understanding the biochemical mechanisms that underlie channel subtype regulation and how such processes may be altered following nerve injury. Small molecule toxins serve as lead compounds for the design of isoform-selective channel modulators, affinity reagents, and fluorescence imaging probes. Access to toxins and modified forms thereof (including saxitoxin, gonyautoxin, batrachotoxin, and veratridine) through de novo synthesis drives studies to elucidate toxin-receptor interactions and to develop new pharmacologic tools to study ion channel function in primary cells and murine pain models. -
Alfredo Dubra, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.
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Laramie Duncan
Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsOur work is at the intersection of statistical genetics, psychiatry, and neuroscience. We use massive datasets and primarily computational approaches to identify mechanisms contributing to mental health problems like schizophrenia and depression. The overall goal of the lab is to discover fundamental information about psychiatric disorders, and ultimately to build more effective approaches to classification, prevention, and treatment.
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Alexander Dunn
Professor of Chemical Engineering
Current Research and Scholarly InterestsMy lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.
